{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:39:42Z","timestamp":1792683582969,"version":"4.5.0"},"reference-count":0,"publisher":"The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS","issue":"3","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turkish Journal of Medical Sciences"],"abstract":"<jats:p>Background\/aim:  This study aimed to report the 5-year outcomes of patients with newly diagnosed branch retinal vein occlusion (BRVO).\nMaterials and methods:  A retrospective review of patient charts was conducted. Data on central macular thickness (CMT), best-corrected visual acuity (BCVA), photoreceptor integrity, number of intravitreal (IV) antivascular endothelial growth factor (anti- VEGF) injections administered, and treatment regimen were assessed.\nResults: Ninety-seven eyes from individual patients with a mean age of 70.90 \u00b1 11.49 (38\u201392) were included. The mean BCVA improved, and the mean CMT decreased at all follow-up visits following treatment (p &lt; 0.05). Thirty-two eyes (33%) gained 3 lines of BCVA at the five-year follow-up. The mean number of total IV anti-VEGF injections administered was 19 \u00b1 13.35 (1\u201349) during the five-year period, and 27.83% of patients received rescue laser treatment. Fifty-four percent of eyes received three consecutive monthly loading doses of IV anti-VEGF injections. The mean change in BCVA in the loading dose (+) group was significantly greater than in the loading dose (\u2013) group at 1-year and subsequent visits. The loading dose (+) group showed a significantly greater reduction in CMT compared to the loading dose (\u2013) group. The mean estimated time for BCVA to decline by \u22653 lines was 117 \u00b1 8.74 months (95% CI = 100.21\u2013134.51)\nConclusion: Anti-VEGF treatment was effective in improving anatomical and functional outcomes in BRVO patients during long-term follow-up. Initial treatment with three loading doses of anti-VEGF resulted in greater vision gain and more pronounced anatomical improvement.<\/jats:p>","DOI":"10.55730\/1300-0144.6008","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T11:06:32Z","timestamp":1750935992000},"page":"613-621","source":"Crossref","is-referenced-by-count":0,"title":["Long-term results of branch retinal vein occlusion: 5-year follow-up"],"prefix":"10.55730","volume":"55","author":[{"given":"ILKAY KILIC","family":"MUFTUOGLU","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NATASHA","family":"MAYER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KATHERINA","family":"DU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CATALINA","family":"FEISTRITZER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ELISE","family":"BARBERIS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SASHWANTI","family":"MOHAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JAY","family":"CHHABLANI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34691","published-online":{"date-parts":[[2025,6,20]]},"container-title":["Turkish Journal of Medical Sciences"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:47:07Z","timestamp":1792680427000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.tubitak.gov.tr\/medical\/vol55\/iss3\/10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,20]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,6,20]]}},"URL":"https:\/\/doi.org\/10.55730\/1300-0144.6008","relation":{},"ISSN":["1300-0144"],"issn-type":[{"value":"1300-0144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,20]]}}}