{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:39:35Z","timestamp":1792683575321,"version":"4.5.0"},"reference-count":0,"publisher":"The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS","issue":"3","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turkish Journal of Medical Sciences"],"abstract":"<jats:p>Background\/aim:  To evaluate the short-term efficacy and safety of nondamaging retinal laser therapy (NRT) for retinitis pigmentosa-associated cystoid macular edema (RP-CME) and analyze anatomical and functional outcomes.\nMaterials and methods:  A retrospective case series of 40 eyes from 30 patients with RP-CME was conducted. The patients underwent NRT using a PASCAL laser system with endpoint management (EpM) software. Central macular thickness (CMT) and best-corrected visual acuity (BCVA) were assessed at baseline and 2 months posttreatment. Long-term follow-up data, including recurrence rates were also reviewed.\nResults: At the 2-month follow-up, NRT significantly reduced mean CMT by 79.7 \u03bcm (p &lt; 0.001) and improved BCVA by 0.10 LogMAR (p &lt; 0.001). Complete resolution of CME was observed in 30% of the eyes, while 52.5% experienced recurrence within 6 months. Unilateral cases exhibited greater CMT reductions than bilateral cases (p &lt; 0.05). No retinal damage from the laser was observed. The long-term sustainability of these effects remains unclear, and repeated treatments have not yet been assessed.\nConclusion: NRT is a safe and effective short-term treatment for RP-CME, achieving significant anatomical and functional improvements without evidence of retinal damage. However, the high recurrence rate and absence of long-term data warrant further investigation. Future studies should explore repeated treatments, genetic subtypes, and correlations with the ellipsoid zone integrity.<\/jats:p>","DOI":"10.55730\/1300-0144.6012","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T11:05:36Z","timestamp":1750935936000},"page":"652-657","source":"Crossref","is-referenced-by-count":2,"title":["Short-term efficacy and safety of nondamaging retinal laser therapy for retinitis pigmentosa-associated cystoid macular edema"],"prefix":"10.55730","volume":"55","author":[{"given":"SEDA","family":"\u00c7EV\u0130K KAYA","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MEHMET","family":"\u00c7ITIRIK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MEVL\u00dcT","family":"YILMAZ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EY\u00dcPCAN","family":"\u015eENSOY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34691","published-online":{"date-parts":[[2025,6,20]]},"container-title":["Turkish Journal of Medical Sciences"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:47:05Z","timestamp":1792680425000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.tubitak.gov.tr\/medical\/vol55\/iss3\/14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,20]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,6,20]]}},"URL":"https:\/\/doi.org\/10.55730\/1300-0144.6012","relation":{},"ISSN":["1300-0144"],"issn-type":[{"value":"1300-0144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,20]]}}}