{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:40:37Z","timestamp":1792590037698,"version":"4.5.0"},"reference-count":0,"publisher":"The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS","issue":"3","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turkish Journal of Chemistry"],"abstract":"<jats:p>In this research, a fast and simple spectrophotometric method is presented for mitoxantrone determination in various aqueous samples. It utilizes preconcentration by salt saturated pipette-tip micro solid phase extraction with a selective molecularly imprinted polymer adsorbent packed in a micropipette tip. Prior to sample loading, they were saturated with a mixture of NaCl, Mg (NO3)2.6H2O and KNO3 salts, enhancing extraction efficiency by 27.5% compared to salt-free conditions. Key microextraction parameters (amount of molecularly imprinted polymer, sample pH, eluent type\/volume, and adsorption\/desorption cycles) were optimized using response surface methodology and one-variable-at-a-time methods. The method achieves a low detection limit (0.2 \u03bcg L\u207b\u00b9) and a wide linear range (1\u20131000 \u03bcg L\u207b\u00b9). An enrichment factor of 49 is obtained with excellent accuracy (relative standard deviation &lt;4.4%). The method was validated by comparing it to a standard high performance liquid chromatography protocol, as well as spiking real samples in three concentration levels. The method successfully detected low levels of mitoxantrone in various water samples.<\/jats:p>","DOI":"10.55730\/1300-0527.3728","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T17:15:15Z","timestamp":1750958115000},"page":"267-278","source":"Crossref","is-referenced-by-count":3,"title":["Determination of mitoxantrone in environmental waters: a spectrophotometric method with preconcentration by salt saturated pipette-tip micro solid phase extraction using molecularly imprinted polymer"],"prefix":"10.55730","volume":"49","author":[{"given":"SAYYED HOSSEIN","family":"HASHEMI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MASSOUD","family":"KAYKHAII","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AHMAD JAMALI","family":"KEIKHA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MINA","family":"ESMAILIUN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"34691","published-online":{"date-parts":[[2025,6,24]]},"container-title":["Turkish Journal of Chemistry"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T12:54:18Z","timestamp":1792587258000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.tubitak.gov.tr\/chem\/vol49\/iss3\/3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,24]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,6,24]]}},"URL":"https:\/\/doi.org\/10.55730\/1300-0527.3728","relation":{},"ISSN":["1300-0527"],"issn-type":[{"value":"1300-0527","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,24]]}}}