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Bruix J, Sherman M, Llovet JM, Beaugrand M, Lencioni R, Burroughs AK, Christensen E, Pagliaro L, Colombo M, Rodes J, HCC EPoEo. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J Hepatol. 2001; 35:421-430.","DOI":"10.1016\/S0168-8278(01)00130-1"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Giannini EG, Savarino V, Farinati F, Ciccarese F, Rapaccini G, Marco MD, Benvegnu L, Zoli M, Borzio F, Caturelli E, Chiaramonte M, Trevisani F, Italian Liver Cancer g. Influence of clinically significant portal hypertension on survival after hepatic resection for hepatocellular carcinoma in cirrhotic patients. Liver Int. 2013; 33:1594-1600.","DOI":"10.1111\/liv.12199"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Jang CW, Kwon HJ, Kong H, Ha H, Han YS, Chun JM, Kim SG, Hwang YJ. 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