{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T20:10:39Z","timestamp":1786565439255,"version":"build-2736575974"},"reference-count":16,"publisher":"International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BST"],"published-print":{"date-parts":[[2023,8,31]]},"DOI":"10.5582\/bst.2023.01160","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T22:13:18Z","timestamp":1689804798000},"page":"318-321","source":"Crossref","is-referenced-by-count":11,"title":["An expanded view of infertility: The challenge of the changing profiling of major birth defects in China"],"prefix":"10.5582","volume":"17","author":[{"given":"Zhongzhong","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Urology, Shanghai Children&apos;s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China."},{"name":"Urogenital Development Research Center, Shanghai Children&apos;s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanlin","family":"Wang","sequence":"additional","affiliation":[{"name":"The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuying","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Urology, Shanghai Children&apos;s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shen","family":"Li","sequence":"additional","affiliation":[{"name":"Beijing Municipal Key Laboratory of Child Development and Nutriomics, Translational Medicine Laboratory, Capital Institute of Pediatrics, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Wang","sequence":"additional","affiliation":[{"name":"Beijing Municipal Key Laboratory of Child Development and Nutriomics, Translational Medicine Laboratory, Capital Institute of Pediatrics, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3542","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Liang S, Chen Y, Wang Q, Chen H, Cui C, Xu X, Zhang Q, Zhang C. Prevalence and associated factors of infertility among 20-49 year old women in Henan Province, China. Reprod Health. 2021; 18:254.","DOI":"10.1186\/s12978-021-01298-2"},{"key":"2","doi-asserted-by":"publisher","unstructured":"2. Qi Q, Gu X, Zhao Y, Chen Z, Zhou J, Chen S, Wang L. The status of surrogacy in China. Biosci Trends. 2023: doi: 10.5582\/bst.2022.01263.","DOI":"10.5582\/bst.2022.01263"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Assidi M. Infertility in men: Advances towards a comprehensive and integrative dtrategy for precision theranostics. Cells. 2022; 11:1711.","DOI":"10.3390\/cells11101711"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Wen SW, Miao Q, Taljaard M, Lougheed J, Gaudet L, Davies M, Lanes A, Leader A, Corsi DJ, Sprague AE, Walker M. Associations of assisted reproductive technology and twin pregnancy with risk of congenital heart fefects. JAMA Pediatr. 2020; 174:446-454.","DOI":"10.1001\/jamapediatrics.2019.6096"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Chen Z-Z, Gao Y-Q, Xie H, Huang Y-C, Chen F, Lei Y-P. Transcription factors dysregulated in three complex birth defects datasets. Reproductive and Developmental Medicine. 2022; 6:79-85.","DOI":"10.1097\/RD9.0000000000000018"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Skarin Nordenvall A, Chen Q, Norrby C, Lundholm C, Frisen L, Nordenstrom A, Almqvist C, Nordenskjold A. Fertility in adult men born with hypospadias: A nationwide register-based cohort study on birthrates, the use of assisted reproductive technologies and infertility. Andrology. 2020; 8:372-380.","DOI":"10.1111\/andr.12723"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Cui M, Lu XL, Lyu YY, Wang F, Xie XL, Cheng XY, Zhang T. Knowledge and intake of folic acid to prevent neural tube defects among pregnant women in urban China: A cross-sectional study. BMC Pregnancy Childbirth. 2021; 21:432.","DOI":"10.1186\/s12884-021-03893-4"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Wang X, Yu J, Wang J. Neural tube defects and folate deficiency: Is DNA Repair Defective? Int J Mol Sci. 2023; 24:2220.","DOI":"10.3390\/ijms24032220"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Milewska EM, Czyzyk A, Meczekalski B, Genazzani AD. Inositol and human reproduction. From cellular metabolism to clinical use. Gynecol Endocrinol. 2016; 32:690-695.","DOI":"10.1080\/09513590.2016.1188282"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Russo M, Forte G, Montanino Oliva M, Lagana AS, Unfer V. Melatonin and myo-inositol: Supporting reproduction from the oocyte to birth. Int J Mol Sci. 2021; 22:8433.","DOI":"10.3390\/ijms22168433"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Lau ES, Wang D, Roberts M, Taylor CN, Murugappan G, Shadyab AH, Schnatz PF, Farland LV, Wood MJ, Scott NS, Eaton CB, Ho JE. Infertility and risk of heart failure in the Women&apos;s Health Initiative. J Am Coll Cardiol. 2022; 79:1594-1603.","DOI":"10.1016\/j.jacc.2022.02.020"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Li Y, Klena NT, Gabriel GC, <i>et al<\/i>. Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015; 521:520-524.","DOI":"10.1038\/nature14269"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Liu X, Chen W, Li W, Priest JR, Fu Y, Pang K, Ma B, Han B, Liu X, Hu S, Zhou Z. Exome-based case-control analysis highlights the pathogenic role of ciliary genes in transposition of the great arteries. Circ Res. 2020; 126:811-821.","DOI":"10.1161\/CIRCRESAHA.119.315821"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Chen Z, Lei Y, Finnell RH, Ding Y, Su Z, Wang Y, Xie H, Chen F. Whole-exome sequencing study of hypospadias. iScience. 2023; 26:106663.","DOI":"10.1016\/j.isci.2023.106663"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Chen Z, Li P, Lyu Y, Wang Y, Gao K, Wang J, Lan F, Chen F. Molecular genetics and general management of androgen insensitivity syndrome. Intractable Rare Dis Res. 2023; 12:71-77.","DOI":"10.5582\/irdr.2023.01024"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Ding Y, Wang Y, Lyu Y, Xie H, Huang Y, Wu M, Chen F, Chen Z. Urogenital sinus malformation: From development to management. Intractable Rare Dis Res. 2023; 12:78-87.","DOI":"10.5582\/irdr.2023.01027"}],"container-title":["BioScience Trends"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bst\/17\/4\/17_2023.01160\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T05:14:01Z","timestamp":1715577241000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/bst\/17\/4\/17_2023.01160\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,31]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.5582\/bst.2023.01160","relation":{},"ISSN":["1881-7815","1881-7823"],"issn-type":[{"value":"1881-7815","type":"print"},{"value":"1881-7823","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,31]]},"article-number":"2023.01160"}}