{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T07:54:32Z","timestamp":1771660472565,"version":"3.50.1"},"reference-count":36,"publisher":"International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["DD&amp;T"],"published-print":{"date-parts":[[2021,12,31]]},"DOI":"10.5582\/ddt.2021.01105","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T22:10:17Z","timestamp":1642198217000},"page":"310-316","source":"Crossref","is-referenced-by-count":6,"title":["Pneumothorax and pneumomediastinum in patients with COVID-19: A retrospective study from tertiary care institute in India"],"prefix":"10.5582","volume":"15","author":[{"given":"Saurav Sekhar","family":"Paul","sequence":"first","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhavesh","family":"Mohan Lal","sequence":"additional","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Animesh","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ved Prakash","family":"Meena","sequence":"additional","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit Kumar","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawan","family":"Tiwari","sequence":"additional","affiliation":[{"name":"Department of Pulmonary, Critical care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant","family":"Sirohiya","sequence":"additional","affiliation":[{"name":"Department of Oncoanesthesia and Palliative Medicine, National Cancer Institute, All India Institute of Medical Sciences, Jhajjar, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saurabh","family":"Vig","sequence":"additional","affiliation":[{"name":"Department of Oncoanesthesia and Palliative Medicine, National Cancer Institute, All India Institute of Medical Sciences, Jhajjar, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sushma","family":"Bhatnagar","sequence":"additional","affiliation":[{"name":"Department of Oncoanesthesia and Palliative Medicine, National Cancer Institute, All India Institute of Medical Sciences, Jhajjar, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anant","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Pulmonary, Critical care and Sleep Medicine, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surabhi","family":"Vyas","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and Intervention Radiology All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naveet","family":"Wig","sequence":"additional","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi, India."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3542","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Gupta A, Madhavan MV, Sehgal K, <i>et al.<\/i> Extrapulmonary manifestations of COVID-19. Nat Med. 2020; 26:1017-1032.","DOI":"10.1038\/s41591-020-0968-3"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Porcel JM. Pleural diseases and COVID-19: ubi fumus, ibi ignis. Eur Respir J. 2020; 56:2003308.","DOI":"10.1183\/13993003.03308-2020"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Bompard F, Monnier H, Saab I, Tordjman M, Abdoul H, Fournier L, Sanchez O, Lorut C, Chassagnon G, Revel MP. Pulmonary embolism in patients with COVID-19 pneumonia. Eur Respir J. 2020; 56:2001365.","DOI":"10.1183\/13993003.01365-2020"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Aayilliath KA, Singh K, Ray A, Wig N. Platypnoea-orthodeoxia syndrome in COVID-19. BMJ Case Rep. 2021; 14:e243016.","DOI":"10.1136\/bcr-2021-243016"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Sarda R, Swain S, Ray A, Wig N. COVID-19 associated Mucormycosis and evolving evidence. QJM. 2021.","DOI":"10.1093\/qjmed\/hcab191"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Al-Ghanem S, Al-Jahdali H, Bamefleh H, Khan AN. Bronchiolitis obliterans organizing pneumonia: pathogenesis, clinical features, imaging and therapy review. Ann Thorac Med. 2008; 3:67-75.","DOI":"10.4103\/1817-1737.39641"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Chen CH, Liao WC, Liu YH, Chen WC, Hsia TC, Hsu WH, Shih CM, Tu CY. Secondary spontaneous pneumothorax: which associated conditions benefit from pigtail catheter treatment? Am J Emerg Med. 2012; 30:45-50.","DOI":"10.1016\/j.ajem.2010.09.014"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Coker RJ, Moss F, Peters B, McCarty M, Nieman R, Claydon E, Mitchell D, Harris JR. Pneumothorax in patients with AIDS. Respir Med. 1993; 87:43-47.","DOI":"10.1016\/S0954-6111(05)80312-9"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. L\u00f3pez-Rivera F, Col\u00f3n Rivera X, Gonz\u00e1lez Monroig HA, Garcia Puebla J. Pneumomediastinum and pneumothorax associated with herpes simplex virus (HSV) pneumonia. Am J Case Rep. 2018; 19:109-113.","DOI":"10.12659\/AJCR.906051"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Olliff JF, Williams MP. Radiological appearances of cytomegalovirus infections. Clin Radiol. 1989; 40:463-467.","DOI":"10.1016\/S0009-9260(89)80245-4"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Sepkowitz KA, Telzak EE, Gold JW, Bernard EM, Blum S, Carrow M, Dickmeyer M, Armstrong D. Pneumothorax in AIDS. Ann Intern Med. 1991; 114:455-459.","DOI":"10.7326\/0003-4819-114-6-455"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Suri T, Makkar N, Ray A, Sood R. A unique case of hydropneumothorax in allergic bronchopulmonary aspergillosis. Med Mycol Case Rep. 2019; 25:29-31.","DOI":"10.1016\/j.mmcr.2019.07.003"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Chu CM, Leung YY, Hui JY, Hung IF, Chan VL, Leung WS, Law KI, Chan CS, Chan KS, Yuen KY. Spontaneous pneumomediastinum in patients with severe acute respiratory syndrome. Eur Respir J. 2004; 23:802-804.","DOI":"10.1183\/09031936.04.00096404"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Das KM, Lee EY, Al Jawder SE, Enani MA, Singh R, Skakni L, Al-Nakshabandi N, AlDossari K, Larsson SG. Acute middle east respiratory syndrome coronavirus: Temporal lung changes observed on the chest radiographs of 55 patients. AJR Am J Roentgenol. 2015; 205:W267-274.","DOI":"10.2214\/AJR.15.14445"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Sihoe AD, Wong RH, Lee AT, Lau LS, Leung NY, Law KI, Yim AP. Severe acute respiratory syndrome complicated by spontaneous pneumothorax. Chest. 2004; 125:2345-2351.","DOI":"10.1378\/chest.125.6.2345"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, Qiu Y, Wang J, Liu Y, Wei Y, Xia J, Yu T, Zhang X, Zhang L. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020; 395:507-513.","DOI":"10.1016\/S0140-6736(20)30211-7"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Yang F, Shi S, Zhu J, Shi J, Dai K, Chen X. Analysis of 92 deceased patients with COVID-19. J Med Virol. 2020; 92:2511-2515.","DOI":"10.1002\/jmv.25891"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Chong WH, Saha BK, Hu K, Chopra A. The incidence, clinical characteristics, and outcomes of pneumothorax in hospitalized COVID-19 patients: A systematic review. Heart Lung. 2021; 50:599-608.","DOI":"10.1016\/j.hrtlng.2021.04.005"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Boussarsar M, Thierry G, Jaber S, Roudot-Thoraval F, Lemaire F, Brochard L. Relationship between ventilatory settings and barotrauma in the acute respiratory distress syndrome. Intensive Care Med. 2002; 28:406-413.","DOI":"10.1007\/s00134-001-1178-1"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Mir\u00f3 \u00d2, Llorens P, Jim\u00e9nez S, <i>et al.<\/i> Frequency, risk factors, clinical characteristics, and outcomes of spontaneous pneumothorax in patients with coronavirus disease 2019: A case-control, emergency medicine-based multicenter study. Chest. 2021; 159:1241-1255.","DOI":"10.1016\/j.chest.2020.11.013"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. McGuinness G, Zhan C, Rosenberg N, Azour L, Wickstrom M, Mason DM, Thomas KM, Moore WH. Increased incidence of barotrauma in patients with COVID-19 on invasive mechanical ventilation. Radiology. 2020; 297:E252-e262.","DOI":"10.1148\/radiol.2020202352"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Lemmers DHL, Abu Hilal M, Bn\u00e0 C, Prezioso C, Cavallo E, Nencini N, Crisci S, Fusina F, Natalini G. Pneumomediastinum and subcutaneous emphysema in COVID-19: barotrauma or lung frailty? ERJ Open Res. 2020; 6:00385-2020.","DOI":"10.1183\/23120541.00385-2020"},{"key":"23","unstructured":"23. WHO. COVID-19 case definition. <i>https:\/\/www.who.int\/publications\/i\/item\/WHO-2019-nCoV<\/i><i>-Surveillance_Case_<\/i><i>Definition-2020.2<\/i> (accessd August 20, 2021)."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Henry M, Arnold T, Harvey J. BTS guidelines for the management of spontaneous pneumothorax. Thorax. 2003; 58 (Suppl 2):ii39-52.","DOI":"10.1136\/thx.58.suppl_2.ii39"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Cerfolio RJ. Recent advances in the treatment of air leaks. Curr Opin Pulm Med. 2005; 11:319-323.","DOI":"10.1097\/01.mcp.0000161056.85290.08"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Borghesi A, Zigliani A, Masciullo R, Golemi S, Maculotti P, Farina D, Maroldi R. Radiographic severity index in COVID-19 pneumonia: relationship to age and sex in 783 Italian patients. Radiol Med. 2020; 125:461-464.","DOI":"10.1007\/s11547-020-01202-1"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Zantah M, Dominguez Castillo E, Townsend R, Dikengil F, Criner GJ. Pneumothorax in COVID-19 disease-incidence and clinical characteristics. Respir Res. 2020; 21:236.","DOI":"10.1186\/s12931-020-01504-y"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Wang XH, Duan J, Han X, Liu X, Zhou J, Wang X, Zhu L, Mou H, Guo S. High incidence and mortality of pneumothorax in critically Ill patients with COVID-19. Heart Lung. 2021; 50:37-43.","DOI":"10.1016\/j.hrtlng.2020.10.002"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Tacconi F, Rogliani P, Leonardis F, Sarmati L, Fabbi E, De Carolis G, La Rocca E, Vanni G, Ambrogi V. Incidence of pneumomediastinum in COVID-19: A single-center comparison between 1<sup>st<\/sup> and 2<sup>nd <\/sup>wave. Respir Investig. 2021; 59:661-665.","DOI":"10.1016\/j.resinv.2021.04.010"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Ray A. A letter in response to recurrent subcutaneous emphysema in a treated tuberculosis patient: Is there any association? Lung India. 2014; 31:312-314.","DOI":"10.4103\/0970-2113.135805"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Xu Z, Shi L, Wang Y, <i>et al.<\/i> Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020; 8:420-422.","DOI":"10.1016\/S2213-2600(20)30076-X"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Peckham H, de Gruijter NM, Raine C, Radziszewska A, Ciurtin C, Wedderburn LR, Rosser EC, Webb K, Deakin CT. Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission. Nat Commun. 2020; 11:6317.","DOI":"10.1038\/s41467-020-19741-6"},{"key":"33","unstructured":"33. Haseli S, Khalili N, Bakhshayeshkaram M, Sanei Taheri M, Moharramzad Y. Lobar distribution of COVID-19 pneumonia based on chest computed tomography findings; A retrospective study. Arch Acad Emerg Med. 2020; 8:e55."},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Nagra D, Russell M, Yates M, Galloway J, Barker R, Desai SR, Norton S. COVID-19: opacification score is higher in the right lung and right lung involvement is a better predictor of ICU admission. Eur Respir J. 2020; 56:2002340.","DOI":"10.1183\/13993003.02340-2020"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35 Yang R, Li X, Liu H, Zhen Y, Zhang X, Xiong Q, Luo Y, Gao C, Zeng W. Chest CT severity score: An imaging tool for assessing severe COVID-19. Radiol Cardiothorac Imaging. 2020; 2:e200047.","DOI":"10.1148\/ryct.2020200047"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36 Shi H, Han X, Jiang N, Cao Y, Alwalid O, Gu J, Fan Y, Zheng C. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis. 2020; 20:425-434.","DOI":"10.1016\/S1473-3099(20)30086-4"}],"container-title":["Drug Discoveries &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ddt\/15\/6\/15_2021.01105\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T03:55:20Z","timestamp":1642218920000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/ddt\/15\/6\/15_2021.01105\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,31]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.5582\/ddt.2021.01105","relation":{},"ISSN":["1881-7831","1881-784X"],"issn-type":[{"value":"1881-7831","type":"print"},{"value":"1881-784X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,31]]},"article-number":"2021.01105"}}