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Zhu J, Chai Z, Wu C, Huang Y, Wu X. Comprehensive research on the quality of <i>Torreya grandis<\/i> and its oil in Zhejiang Province. J Chin Cereals Oils Assoc. 2019; 34:67-73."},{"key":"2","unstructured":"2. Li SZ. Fruit. In: Compendium of Materia Medica (Vol. 31). China, 1593; pp. 1080."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Lou H, Zheng S, Chen W, Yu W, Jiang H, Farag MA, Xiao J, Wu J, Song L. Transcriptome-referenced association study provides insights into the regulation of oil and fatty acid biosynthesis in <i>Torreya grandis<\/i> kernel. J Adv Res. 2024; 62:1-14.","DOI":"10.1016\/j.jare.2023.01.007"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Xiao M, Huang M, Huan W, Dong J, Xia J, Wu J, Wang D, Song L. Effects of <i>T. grandis<\/i> kernel oil on lipid metabolism and intestinal flora in C57BL\/6J mice. Oxid Med Cell Longev. 2022; 4472751.","DOI":"10.1155\/2022\/4472751"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Dong D, Wang H, Xu F, Xu C, Shao X, Li H. Supercritical carbon dioxide extraction, fatty acid composition, oxidative stability, and antioxidant effect of <i>Torreya grandis<\/i> seed oil. J Am Oil chem Soc. 2014; 91:817-825.","DOI":"10.1007\/s11746-014-2419-0"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Chen BQ, Cui XY, Zhao X, Zhang YH, Piao HS, Kim JH, Lee BC, Pyo HB, Yun YP. Antioxidative and acute antiinflammatory effects of <i>Torreya grandis<\/i>. Fitoterapia. 2006; 77:262-267.","DOI":"10.1016\/j.fitote.2006.03.019"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Zhu MF, Tu ZC, Zhang L, Liao H. Antioxidant, metabolic enzymes inhibitory ability of <i>Torreya grandis<\/i> kernels, and phytochemical profiling identified by HPLC-QTOF-MS\/MS. J Food Biochem. 2019; 43:e13043.","DOI":"10.1111\/jfbc.13043"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Laghari AH, Kandhro AA, Memon AA. Chapter 4 - Cold pressed <i>Torreya grandis<\/i> kernel oil. In: Cold pressed oils: Green technology, bioactive compounds, functionality, and applications (Ramadan MF eds.). Academic Press, 2020; pp. 31-38.","DOI":"10.1016\/B978-0-12-818188-1.00004-9"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Ding M, Lou H, Chen W, Zhou Y, Zhang Z, Xiao M, Wang Z, Yang Y, Yang L, Zhang F, Wu J, Song L. Comparative transcriptome analysis of the genes involved in lipid biosynthesis pathway and regulation of oil body formation in <i>Torreya grandis<\/i> kernels. Ind Crops Prod. 2020; 145:112051.","DOI":"10.1016\/j.indcrop.2019.112051"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Cui HX, Duan FF, Jia SS, Cheng FR, Yuan K. Antioxidant and tyrosinase inhibitory activities of seed oils from <i>Torreya grandis<\/i> Fort. ex Lindl. Biomed Res Int. 2018; 2018:5314320.","DOI":"10.1155\/2018\/5314320"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Wang Y, Yao X, Yang L, Fei X, Cao Y, Wang K, Guo S. Effects of harvest time on the yield, quality and active substance of <i>Torreya grandis<\/i> nut and its oil. J Oleo Sci. 2021; 70:175-184.","DOI":"10.5650\/jos.ess20155"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Lou H, Ding M, Wu J, Zhang F, Chen W, Yang Y, Suo J, Yu W, Xu C, Song L. Full-length transcriptome analysis of the genes involved in tocopherol biosynthesis in <i>Torreya grandis<\/i>. J Agric Food Chem. 2019; 67:1877-1888.","DOI":"10.1021\/acs.jafc.8b06138"},{"key":"13","unstructured":"13. Ren C, Zhang Y, Tang F, Shen D, Mo R. Analysis of main chemical components in camellia oil, olive oil, walnut oil and <i>Torreya<\/i> seeds oil. J Food Saf Qual. 2015; 6:5011-5016."},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Wu F, Luo X, Zhang Y, Wang P, Chang Y, He Z, Liu X. Purification, identification, and inhibitory mechanisms of a novel ACE inhibitory peptide from <i>Torreya grandis<\/i>. Nutrients. 2023; 15:2374.","DOI":"10.3390\/nu15102374"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Zongo AW, Jin C, Hao G, Yu N, Zogona D, Nie X, Lu Y, Ye Q, Meng X. Functional compounds of <i>Torreya grandis<\/i> nuts and their processing byproducts: Extraction process, health benefits, and food applications - A comprehensive review. Food Res Int. 2024; 197(Pt 1):115232.","DOI":"10.1016\/j.foodres.2024.115232"},{"key":"16","unstructured":"16. Ni L, Shi WY. Composition and free radical scavenging activity of kernel oil from <i>Torreya grandis<\/i>, <i>Carya cathayensis<\/i>, and <i>Myrica rubra<\/i>. Iran J Pharm Res. 2014; 13:221-226."},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Zhang F, Ma Z, Qiao Y, Wang Z, Chen W, Zheng S, Yu C, Song L, Lou H, Wu J. Transcriptome sequencing and metabolomics analyses provide insights into the flavonoid biosynthesis in <i>Torreya grandis<\/i> kernels. Food Chem. 2022; 374:131558.","DOI":"10.1016\/j.foodchem.2021.131558"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Ikram M, Muhammad T, Rehman SU, Khan A, Jo MG, Ali T, Kim MO. Hesperetin confers neuroprotection by regulating Nrf2\/TLR4\/NF-\u03baB signaling in an A\u03b2 mouse model. Mol Neurobiol. 2019; 56:6293-6309.","DOI":"10.1007\/s12035-019-1512-7"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Escribano-Ferrer E, Queralt Regu\u00e9 J, Garcia-Sala X, Boix Monta\u00f1\u00e9s A, Lamuela-Raventos RM. <i>In vivo<\/i> anti-inflammatory and antiallergic activity of pure naringenin, naringenin chalcone, and quercetin in mice. J Nat Prod. 2019; 82:177-182.","DOI":"10.1021\/acs.jnatprod.8b00366"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Tao H, Zhu M, Chen M, Liu K, Zhang Z, Song L, Gao F. Diversity of flavonoids in five <i>Torreya grandis<\/i> cultivars: Integrating metabolome and transcriptome to elucidate potential applications for health and metabolic engineering. Food Res Int. 2024; 198:115374.","DOI":"10.1016\/j.foodres.2024.115374"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Yao J, Bai E, Duan Y, Huang Y. Ethanol extracts from <i>Torreya grandis<\/i> seed have potential to reduce hyperuricemia in mouse models by influencing purine metabolism. Foods. 2024; 13:840.","DOI":"10.3390\/foods13060840"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Suo J, Tong K, Wu J, Ding M, Chen W, Yang Y, Lou H, Hu Y, Yu W, Song L. Comparative transcriptome analysis reveals key genes in the regulation of squalene and \u03b2-sitosterol biosynthesis in <i>Torreya grandis<\/i>. Ind Crop Prod. 2019; 131:182-193.","DOI":"10.1016\/j.indcrop.2019.01.035"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Fox CB. Squalene emulsions for parenteral vaccine and drug delivery. Molecules. 2009; 14:3286-3312.","DOI":"10.3390\/molecules14093286"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Hu Y, Suo J, Jiang G, Shen J, Cheng H, Lou H, Yu W, Wu J, Song L. The effect of ethylene on squalene and \u03b2-sitosterol biosynthesis and its key gene network analysis in <i>Torreya grandis<\/i> nuts during post-ripening process. Food Chem. 2022; 368:130819.","DOI":"10.1016\/j.foodchem.2021.130819"},{"key":"25","unstructured":"25. Yang L, Zhao D, Hu Y, Suo J, Yu W, Wu J, Lou H, Song L. Comparative analysis of aroma components and oil quality of <i>Torreya grandis<\/i> &apos;Merrillii&apos; nuts with different processing techniques. Zhejiang Nong Lin Da Xue Xue Bao. 2022; 39:22-31. (in Chinese)"},{"key":"26","unstructured":"26. Wei X, Hu Y, Zhu G, Yu W, Zhang Z, Wu J, Song L. Effects of different shedding time on aroma and nutrients of <i>Torreya grandis<\/i> &apos;Merrillii&apos; seed kernel. Nanjing Lin Ye Da Xue Xue Bao. 2024; 48:51-60. (in Chinese)"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Hu Y, Zhang Z, Hua B, Tao L, Chen W, Gao Y, Suo J, Yu W, Wu J, Song L. The interaction of temperature and relative humidity affects the main aromatic components in postharvest <i>Torreya grandis<\/i> nuts. Food Chem. 2022; 368:130836.","DOI":"10.1016\/j.foodchem.2021.130836"},{"key":"28","unstructured":"28. Zhang C, Fang X, Chen Z, Luo F, Zhong H, Du M. Effects of processing process on the composition of volatile substances in <i>Torreya<\/i> seed oil. China Oils Fats. 2024; 49:22-28."},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Neagu E, Radu GL, Albu C, Paun G. Antioxidant activity, acetylcholinesterase and tyrosinase inhibitory potential of <i>Pulmonaria officinalis<\/i> and <i>Centarium umbellatum<\/i> extracts. Saudi J Biol Sci. 2018; 25:578-585.","DOI":"10.1016\/j.sjbs.2016.02.016"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Quan W, Xu Y, Xie Y, Peng F, Lin Y. <i>In vitro<\/i> antioxidant properties and phenolic profile of acid aqueous ethanol extracts from <i>Torreya grandis<\/i> seed coat. Molecules. 2022; 27:5560.","DOI":"10.3390\/molecules27175560"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Wang H, Zheng Y, Tang X, Zhang T. Formulation of a stable oil-in-water microemulsion of <i>Torreya grandis<\/i> cv. Merrillii aril essential oil and its application in loquat fruit preservation. Foods. 2023; 12:4005.","DOI":"10.3390\/foods12214005"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Durrani R, Meiyun Y, Yang B, Durand E, Delavault A, Bowen H, Weiwei H, Yiyang L, Lili S, Fei G. Identification of novel bioactive proteins and their produced oligopeptides from <i>Torreya grandis<\/i> nuts using proteomic based prediction. Food Chem. 2023; 405(Pt A):134843.","DOI":"10.1016\/j.foodchem.2022.134843"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Yan J, Zeng H, Chen W, Zheng S, Luo J, Jiang H, Yang B, Farag M, Lou H, Song L, Wu J. Effects of tree age on flavonoids and antioxidant activity in <i>Torreya grandis<\/i> nuts <i>via<\/i> integrated metabolome and transcriptome analyses. Food Frontiers. 2023; 4:358-367.","DOI":"10.1002\/fft2.211"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Saeed MK, Deng Y, Dai R, Li W, Yu Y, Iqbal Z. Appraisal of antinociceptive and anti-inflammatory potential of extract and fractions from the leaves of <i>Torreya grandis<\/i> Fort Ex. Lindl. J Ethnopharmacol. 2010; 127:414-418.","DOI":"10.1016\/j.jep.2009.10.024"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35. Gao Y, Yang J, Zhang Y, Gao L, Tian J, Han W, Gao J. Abietane-type diterpenoids from the arils of <i>Torreya grandis<\/i>. Molecules. 2024; 29:1905.","DOI":"10.3390\/molecules29091905"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Chen SJ, Huang WC, Yang TT, Lu JH, Chuang LT. Incorporation of sciadonic acid into cellular phospholipids reduces pro-inflammatory mediators in murine macrophages through NF-\u03baB and MAPK signaling pathways. Food Chem Toxicol. 2012; 50:3687-3695.","DOI":"10.1016\/j.fct.2012.07.057"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Yao S, Lu H, Zhou T, Jiang Q, Jiang C, Hu W, Li M, Tan CP, Feng Y, Du Q, Shen G, Xiang X, Chen L. Sciadonic acid attenuates high-fat diet-induced bone metabolism disorders in mice. Food Funct. 2024; 15:4490-4502.","DOI":"10.1039\/D3FO04527G"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Yang L, Hu Y, Deng H, Li Y, Zhang R, Zhang Q, Yang L, Pang H, Liu F, Fu C. Water-soluble polysaccharides from <i>Torreya grandis<\/i> nuts: Structural characterization and anti-inflammatory activity. Int J Biol Macromol. 2025; 291:138935.","DOI":"10.1016\/j.ijbiomac.2024.138935"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Cui JJ, Li WJ, Wang CL, Huang YQ, Lin W, Zhou B, Yue JM. Antimicrobial abietane-type diterpenoids from <i>Torreya grandis<\/i>. Phytochemistry. 2022; 201:113278.","DOI":"10.1016\/j.phytochem.2022.113278"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Chen L, Jiang Q, Jiang C, Lu H, Hu W, Yu S, Li M, Tan CP, Feng Y, Xiang X, Shen G. Sciadonic acid attenuates high-fat diet-induced obesity in mice with alterations in the gut microbiota. Food Funct. 2023; 14:2870-2880.","DOI":"10.1039\/D2FO02524H"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41. Li XQ, Jia SS, Yuan K, Jin SH. Hypoglycemic effect of the n-butanol fraction of <i>Torreya grandis<\/i> leaves on type 2 diabetes mellitus in rats through the amelioration of oxidative stress and enhancement of <i>\u03b2<\/i>-cell function. Biomed Res Int. 2022; 2022:5648896.","DOI":"10.1155\/2022\/5648896"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42. Endo Y, Osada Y, Kimura F, Shirakawa H, Fujimoto K. Effects of Japanese Torreya (<i>Torreya nucifera<\/i>) seed oil on the activities and mRNA expression of lipid metabolism-related enzymes in rats. Biosci Biotechnol Biochem. 2007; 71:231-233.","DOI":"10.1271\/bbb.60350"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43. Ma J, Yuan T, Gao Y, Zeng X, Liu Z, Gao J. <i>Torreya grandis<\/i> oil attenuates cognitive impairment in scopolamine-induced mice. Food Funct. 2023; 14:10520-10534.","DOI":"10.1039\/D3FO03800A"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44. Thakur S, Dhapola R, Sarma P, Medhi B, Reddy DH. Neuroinflammation in Alzheimer&apos;s disease: current progress in molecular signaling and therapeutics. Inflammation. 2023; 46:1-17.","DOI":"10.1007\/s10753-022-01721-1"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45. Galloway S, Takechi R, Nesbit M, Pallebage-Gamarallage MM, Lam V, Mamo JCL. The differential effects of fatty acids on enterocytic abundance of amyloid-beta. Lipids Health Dis. 2019; 18:209.","DOI":"10.1186\/s12944-019-1162-9"},{"key":"46","doi-asserted-by":"crossref","unstructured":"46. Howe AM, Burke S, O&apos;Reilly ME, McGillicuddy FC, Costello DA. Palmitic acid and oleic acid differently modulate TLR2-mediated inflammatory responses in microglia and macrophages. Mol Neurobiol. 2022; 59:2348-2362.","DOI":"10.1007\/s12035-022-02756-z"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47. Garc\u00eda-Cerro S, Rueda N, Vidal V, Puente A, Campa V, Lantigua S, Narc\u00eds O, Velasco A, Bartesaghi R, Mart\u00ednez-Cu\u00e9 C. Prenatal administration of oleic acid or linolenic acid reduces neuromorphological and cognitive alterations in Ts65dn Down Syndrome mice. J Nutr. 2020; 150:1631-1643.","DOI":"10.1093\/jn\/nxaa074"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48. Ali W, Ikram M, Park HY, Jo MG, Ullah R, Ahmad S, Abid NB, Kim MO. Oral administration of alpha linoleic acid rescues A\u03b2-Induced glia-mediated neuroinflammation and cognitive dysfunction in C57BL\/6N mice. Cells. 2020; 9:667.","DOI":"10.3390\/cells9030667"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49. Silva YP, Bernardi A, Frozza RL. The role of short-chain fatty acids from gut microbiota in gut-brain communication. Front Endocrinol (Lausanne). 2020; 11:25.","DOI":"10.3389\/fendo.2020.00025"},{"key":"50","doi-asserted-by":"crossref","unstructured":"50. Ebanks JP, Wickett RR, Boissy RE. Mechanisms regulating skin pigmentation: the rise and fall of complexion coloration. Int J Mol Sci. 2009; 10:4066-4087.","DOI":"10.3390\/ijms10094066"},{"key":"51","doi-asserted-by":"crossref","unstructured":"51. Ramsden CA, Riley PA. Tyrosinase: the four oxidation states of the active site and their relevance to enzymatic activation, oxidation and inactivation. Bioorg Med Chem. 2014; 22:2388-2395.","DOI":"10.1016\/j.bmc.2014.02.048"},{"key":"52","doi-asserted-by":"crossref","unstructured":"52. Yamaguchi Y, Brenner M, Hearing VJ. The regulation of skin pigmentation. J Biol Chem. 2007; 282:27557-27561.","DOI":"10.1074\/jbc.R700026200"},{"key":"53","doi-asserted-by":"crossref","unstructured":"53. Feng T, Hu Z, Song S, Yao L, Sun M, Zhu X, Lu J. The antioxidant and tyrosinase inhibition properties of essential oil from the peel of Chinese <i>Torreya grandis<\/i> Fort. RSC Adv. 2019; 9:42360-42366.","DOI":"10.1039\/C9RA06664K"},{"key":"54","doi-asserted-by":"crossref","unstructured":"54. Zolghadri S, Bahrami A, Hassan Khan MT, Munoz-Munoz J, Garcia-Molina F, Garcia-Canovas F, Saboury AA. A comprehensive review on tyrosinase inhibitors. J Enzyme Inhib Med Chem. 2019; 34:279-309.","DOI":"10.1080\/14756366.2018.1545767"},{"key":"55","doi-asserted-by":"crossref","unstructured":"55. Wang X, Guo R, Yu Z, Zikela L, Li J, Li S, Han Q. <i>Torreya grandis<\/i> kernel oil alleviates loperamide-induced slow transit constipation <i>via<\/i> up-regulating the colonic expressions of Occludin\/Claudin-1\/ZO-1 and 5-HT3R\/5-HT4R in BALB\/c mice. Mol Nutr Food Res. 2024; 68:e2300615.","DOI":"10.1002\/mnfr.202300615"},{"key":"56","unstructured":"56. Chen Z, Ni Z, Mo R., Zhong D, Tang F. Comprehensive evaluation on quality of oils from seven kinds of woody oilcrops. China Oils Fats. 2018; 43:80-85."},{"key":"57","unstructured":"57. Wu F, Han Q, Yu Y, Ni S. GC-MS analysis of fatty acids from <i>Torreya grandis<\/i> and <i>Camellia oleifera<\/i> seed. 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