{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T01:15:15Z","timestamp":1648862115856},"reference-count":10,"publisher":"International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IRDR"],"published-print":{"date-parts":[[2021,11,30]]},"DOI":"10.5582\/irdr.2021.01103","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T22:09:16Z","timestamp":1632521356000},"page":"292-293","source":"Crossref","is-referenced-by-count":0,"title":["GPR30: A new potential therapeutic target in human testicular germ cell tumors"],"prefix":"10.5582","volume":"10","author":[{"given":"Paolo","family":"Chieffi","sequence":"first","affiliation":[{"name":"Dipartimento di Psicologia, Universit\u00e0 della Campania, Caserta, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3542","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Chieffi P, De Martino M, Esposito F New anti-cancer strategies in testicular germ cell tumors. Recent Pat Anticancer Drug Discov. 2019; 14:53-59.","DOI":"10.2174\/1574892814666190111120023"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Chieffi P. An up-date on novel molecular targets in testicular germ cell tumors subtypes. Intractable Rare Dis Res. 2019; 8:161-164.","DOI":"10.5582\/irdr.2019.01055"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Jacenik D, Cygankiewicz AI, Krajewska WM. The G protein-coupled estrogen receptor as a modulator of neoplastic transformation. Mol Cell Endocrinol. 2016; 429:10-18.","DOI":"10.1016\/j.mce.2016.04.011"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Sinisi AA, Chieffi P, Pasquali D, Kisslinger A, Staibano S, Bellastella A, Tramontano D. EPN: a novel epithelial cell line derived from human prostate tissue. In Vitro Cell Dev Biol Anim. 2002; 38:165-172.","DOI":"10.1290\/1071-2690(2002)038<0165:EANECL>2.0.CO;2"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Esposito F, Boscia F, Franco R, Tornincasa M, Fusco A, Kitazawa S, Looijenga LH, Chieffi P. Down-regulation of oestrogen receptor-\u03b2 associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas. J Pathol. 2011; 224:110-120.","DOI":"10.1002\/path.2846"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Esposito F, Boscia F, Gigantino V, Tornincasa M, Fusco A, Franco R, Chieffi P. The high-mobility group A1-estrogen receptor \u03b2 nuclear interaction is impaired in human testicular seminomas. J Cell Physiol. 2012; 227:3749-3755.","DOI":"10.1002\/jcp.24087"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Chimento A, De Luca A, Nocito MC, Avena P, La Padula D, Zavaglia L, Pezzi V. Role of GPER-Mediated Signaling in Testicular Functions and Tumorigenesis. Cells. 2020; 9:2115.","DOI":"10.3390\/cells9092115"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Pepermans RA, Sharma G, Prossnitz ER. G protein-coupled estrogen receptor in cancer and stromal cells: functions and novel therapeutic perspectives. Cells. 2021; 10:672.","DOI":"10.3390\/cells10030672"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Boscia F, Passaro C, Gigantino V, Perdon\u00e0 S, Franco R, Portella G, Chieffi S, Chieffi P. High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness. J Cell Physiol. 2015; 230:1290-1297.","DOI":"10.1002\/jcp.24864"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Vaucher L, Funaro MG, Mehta A, Mielnik A, Bolyakov A, Prossnitz ER, Schlegel PN, Paduch DA. Activation of GPER-1 estradiol receptor downregulates production of testosterone in isolated rat Leydig cells and adult human testis. PLoS One. 2014; 9:e92425.","DOI":"10.1371\/journal.pone.0092425"}],"container-title":["Intractable &amp; Rare Diseases Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/irdr\/10\/4\/10_2021.01103\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T04:26:22Z","timestamp":1638591982000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/irdr\/10\/4\/10_2021.01103\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,30]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.5582\/irdr.2021.01103","relation":{},"ISSN":["2186-361X","2186-3644"],"issn-type":[{"value":"2186-361X","type":"electronic"},{"value":"2186-3644","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11,30]]},"article-number":"2021.01103"}}