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J Gastroenterol Hepatol. 1991; 6:471-475.","DOI":"10.1111\/j.1440-1746.1991.tb00890.x"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Kitano S, Iso Y, Iwanaga T, Koyanagi N, Sugimachi K. Esophageal transection may well be the approach of choice for patient with portal venous obstruction and esophageal varices. Jpn J Surg. 1989; 19:418-423.","DOI":"10.1007\/BF02471622"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Pande GK, Reddy VM, Kar P, Sahni P, Berry M, Tandon BN, Nundy S. Operations for portal hypertension due to extrahepatic obstruction: results and 10 year follow up. Br Med J (Clin Res Ed). 1987; 295:1115-1117.","DOI":"10.1136\/bmj.295.6606.1115"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Plessier A, Darwish-Murad S, Hernandez-Guerra M, <i>et al.<\/i> Acute portal vein thrombosis unrelated to cirrhosis: A prospective multicenter follow-up study. 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