{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T01:10:26Z","timestamp":1789434626537,"version":"build-2803163510"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:p><jats:bold>OBJECTIVE:<\/jats:bold> To systematically screen older rural populations in Cambodia for tuberculosis (TB) and develop an effective active case-finding (ACF) model for this TB high-risk group.<jats:bold>DESIGN:<\/jats:bold> A retrospective study using routinely collected programmatic data on community-based\n ACF among people aged \u226555 years using TB symptoms and systematic chest radiography (CXR) screening, followed by Xpert<jats:sup>\u00ae<\/jats:sup> MTB\/RIF testing for participants with positive screening results and TB culture for certain Xpert-negative specimens.<jats:bold>RESULTS:<\/jats:bold> Of 22\u2009101\n participants included in the analysis, 7469 (33.8%) were screening-positive and 5960 (27.0%) underwent Xpert testing. Pulmonary TB was identified in 482 (2.2%) individuals: 288 (1.3%) were bacteriologically confirmed (253 using Xpert, 35 using culture) and 194 (0.9%) were clinically diagnosed.\n Eighty-seven people needed to be screened in order to diagnose one Xpert-positive case. Among the Xpert-positive cases, only 31.6% (80\/253) reported cough \u22652 weeks, and 39.9% (101\/253) were asymptomatic but had a CXR suggestive of active TB. Treatment uptake was 97.3% (469\/482), and treatment\n success was 88.0% (424\/482).<jats:bold>CONCLUSIONS:<\/jats:bold> Community-based ACF was effective in detecting and successfully treating older TB patients, most of whom might otherwise have remained undiagnosed. Mobile CXR appears to be crucial in identifying a high number of asymptomatic, bacteriologically\n confirmed cases.<\/jats:p>","DOI":"10.5588\/ijtld.18.0611","type":"journal-article","created":{"date-parts":[[2019,10,19]],"date-time":"2019-10-19T00:55:51Z","timestamp":1571446551000},"page":"1107-1114","source":"Crossref","is-referenced-by-count":14,"title":["Mobile community-based active case-finding for tuberculosis among older populations in rural Cambodia"],"prefix":"10.5588","volume":"23","author":[{"given":"O.","family":"Camelique","sequence":"first","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res, Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Scholtissen","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res, Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-P.","family":"Dousset","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res, Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bonnet","sequence":"additional","affiliation":[{"name":"Institut de Recherche pour le D\u00e9veloppement (IRD UMI233) Translational Research for Human Immunodeficiency Virus and Infectious Diseases (TransVIHMI), Institut national de la sant\u00e9 et de la recherche m\u00e9dicale Unit\u00e9 1175,\n Montpellier"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bastard","sequence":"additional","affiliation":[{"name":"Epicentre, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Hewison","sequence":"additional","affiliation":[{"name":"M\u00e9decins Sans Fronti\u00e8res, Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2019\/00000023\/00000010\/art00011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,19]],"date-time":"2019-10-19T00:55:58Z","timestamp":1571446558000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.18.0611"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,1]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10,1]]}},"alternative-id":["1027-3719(20191001)23:10L.1107;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.18.0611","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10,1]]}}}