{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:48:08Z","timestamp":1791384488416,"version":"4.3.3"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Individuals with both diabetes mellitus (DM) and TB infection are at higher risk of progressing to TB disease.<jats:bold>OBJECTIVE:<\/jats:bold> To determine DM prevalence in populations at high risk for latent TB infection (LTBI) and to identify the most accurate point-of-care\n (POC) method for DM screening.<jats:bold>METHODS:<\/jats:bold> Adults aged \u226525 years were recruited at health department clinics in Hawaii and Arizona, USA, and screened for LTBI and DM. Screening methods for DM included self-report, random blood glucose (RBG), and POC hemoglobin A1c (HbA1c). Using\n HbA1c \u22656.5% or self-reported history as the gold standard for DM, we compared test strategies to determine the most accurate method while keeping test costs low.<jats:bold>RESULTS:<\/jats:bold> Of 472 participants, 13% had DM and half were unaware of their diagnosis. Limiting HbA1c testing to ages \u226530\n years with a RBG level of 120\u2013180 mg\/dL helped identify most participants with DM (sensitivity 85%, specificity 99%) at an average test cost of US$2.56 per person compared to US$9.56 per person using HbA1c for all patients.<jats:bold>CONCLUSION:<\/jats:bold> Self-report was insufficient\n to determine DM status because many participants were previously undiagnosed. Using a combination of POC RBG and HbA1c provided an inexpensive option to assess DM status in persons at high risk for LTBI.<\/jats:p>","DOI":"10.5588\/ijtld.21.0013","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T04:34:54Z","timestamp":1624941294000},"page":"547-553","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of point-of-care algorithms to detect diabetes during screening for latent TB infection"],"prefix":"10.5588","volume":"25","author":[{"given":"A.","family":"Largen","sequence":"first","affiliation":[{"name":"Tuberculosis Control Program, Hawaii Department of Health, Honolulu, HI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Ayala","sequence":"additional","affiliation":[{"name":"Maricopa County Department of Public Health, Phoenix, AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Khurana","sequence":"additional","affiliation":[{"name":"Maricopa County Department of Public Health, Phoenix, AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Katz","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. K.","family":"Venkatappa","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Brostrom","sequence":"additional","affiliation":[{"name":"Tuberculosis Control Program, Hawaii Department of Health, Honolulu, HI, Centers for Disease Control and Prevention, Atlanta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Tuberculosis Epidemiologic Studies Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2021\/00000025\/00000007\/art00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T04:35:08Z","timestamp":1624941308000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.21.0013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,1]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7,1]]}},"alternative-id":["1027-3719(20210701)25:7L.547;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.21.0013","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7,1]]}}}