{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:46:27Z","timestamp":1761129987388},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Although the burden of TB is lower in France than in low-income countries, patients continue to die from TB in Paris. Our goal was to describe TB-related deaths and to identify associated risk factors.<jats:bold>METHODS:<\/jats:bold> We conducted a retrospective cohort study in\n two hospitals in Paris between 2013 and 2018. All patients with drug-susceptible TB were included and followed until end of treatment. The primary outcome was death. We performed univariate and multivariate analysis using Cox proportional hazard model.<jats:bold>RESULTS:<\/jats:bold> Of the 523 patients\n included, 362 were men (median age 37 years), of whom 24 patients died (4.5%). The final survival model concluded that age (HR 1.1 for each additional year), not living in one\u00b4s own accommodation (HR 5.9), being born in France (HR 8.0), being alcoholic (HR 4.2), having a history of cancer\n (HR 7.1) or meningeal or miliary TB (HR 8.2) were associated with a higher risk of death.<jats:bold>CONCLUSION:<\/jats:bold> The rate of TB-associated death is unacceptably high for a curable disease. To note, patients born in France were much more at risk of death than immigrants. We believe raising awareness\n among healthcare professionals is a potentially easy and efficient lever for improving care.<\/jats:p>","DOI":"10.5588\/ijtld.21.0463","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T04:31:33Z","timestamp":1643344293000},"page":"142-149","source":"Crossref","is-referenced-by-count":5,"title":["Why are people still dying of drug-susceptible TB in Paris in the 21<sup>st<\/sup> century?"],"prefix":"10.5588","volume":"26","author":[{"given":"A-L.","family":"Beaumont","sequence":"first","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Saint-Antoine, F-75012, Groupes hospitalo-universitaires (GHU), Assistance Publique \u2013 H\u00f4pitaux de Paris (AP-HP), Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Doumbia","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Saint-Antoine, F-75012, Groupes hospitalo-universitaires (GHU), Assistance Publique \u2013 H\u00f4pitaux de Paris (AP-HP), Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Ch\u00e2teau","sequence":"additional","affiliation":[{"name":"Institut Pierre Louis d\u00b4Epid\u00e9miologie et de Sant\u00e9 Publique, UMR-S 1136, Institut national de la sant\u00e9 et de la recherche m\u00e9dicale, F-75012, Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J-L.","family":"Meynard","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Saint-Antoine, F-75012, Groupes hospitalo-universitaires (GHU), Assistance Publique \u2013 H\u00f4pitaux de Paris (AP-HP), Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Pacanowski","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Saint-Antoine, F-75012, Groupes hospitalo-universitaires (GHU), Assistance Publique \u2013 H\u00f4pitaux de Paris (AP-HP), Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Valin","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Saint-Antoine, F-75012, Groupes hospitalo-universitaires (GHU), Assistance Publique \u2013 H\u00f4pitaux de Paris (AP-HP), Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Cadranel","sequence":"additional","affiliation":[{"name":"Service de Pneumologie, H\u00f4pital Tenon, F-75020, GHU AP-HP, Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Lalande","sequence":"additional","affiliation":[{"name":"Service de Bact\u00e9riologie-Hygi\u00e8ne, H\u00f4pital Saint-Antoine, F-75012, GHU AP-HP, Sorbonne Universit\u00e9, AP-HP, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Verdet","sequence":"additional","affiliation":[{"name":"Service de Bact\u00e9riologie-Hygi\u00e8ne, H\u00f4pital Saint-Antoine, F-75012, GHU AP-HP, Sorbonne Universit\u00e9, AP-HP, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Lassel","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Tenon, F-75020, GHU AP-HP, Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Pialoux","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Tenon, F-75020, GHU AP-HP, Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Fain","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, H\u00f4pital Saint-Antoine, GHU AP-HP, Sorbonne Universit\u00e9, F-75012, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Morgand","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, H\u00f4pital Saint-Antoine, GHU AP-HP, Sorbonne Universit\u00e9, F-75012, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Lacombe","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Saint-Antoine, F-75012, Groupes hospitalo-universitaires (GHU), Assistance Publique \u2013 H\u00f4pitaux de Paris (AP-HP), Sorbonne Universit\u00e9, Paris, France, Institut Pierre\n Louis d\u00b4Epid\u00e9miologie et de Sant\u00e9 Publique, UMR-S 1136, Institut national de la sant\u00e9 et de la recherche m\u00e9dicale, F-75012, Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Surgers","sequence":"additional","affiliation":[{"name":"Service des Maladies Infectieuses et Tropicales, H\u00f4pital Saint-Antoine, F-75012, Groupes hospitalo-universitaires (GHU), Assistance Publique \u2013 H\u00f4pitaux de Paris (AP-HP), Sorbonne Universit\u00e9, Paris, France, Institut Pierre\n Louis d\u00b4Epid\u00e9miologie et de Sant\u00e9 Publique, UMR-S 1136, Institut national de la sant\u00e9 et de la recherche m\u00e9dicale, F-75012, Sorbonne Universit\u00e9, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung 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