{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T06:46:52Z","timestamp":1648882012327},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Data on the impact of incomplete contact investigation on TB incidence among healthcare professionals (HCPs) after TB exposure are limited.<jats:bold>METHODS:<\/jats:bold> This was a prospective cohort study with 2-year follow-up among Thai HCPs exposed to TB to determine TB incidences\n and factors associated with TB development.<jats:bold>RESULTS:<\/jats:bold> Of the 398 HCPs with TB exposure, 367 (92%) participated in the study; 342 HCPs were included in the final analysis; 311 participated in contact investigations; 303 underwent chest X-ray; 252 completed baseline TB and latent TB\n infection screening using tuberculin skin test (TST); 210 had negative baseline TST; and 45 completed follow-up tests at 3 months. Altogether, 20 HCPs developed TB (2.92\/100 person-years). TB incidences in HCPs not participating in or not completing the investigation at any step were higher\n than in those who completed the evaluation (11.29 and 2.90, respectively, vs. 0\/100 person-years; <jats:italic>P<\/jats:italic> &lt; 0.05). No participation in contact investigation and no baseline chest X-ray were independent factors associated with TB development (adjusted odds ratio [aOR] 6.7; <jats:italic>P<\/jats:italic> &lt;\n 0.001 and aOR 8.9; <jats:italic>P<\/jats:italic> = 0.01, respectively).<jats:bold>CONCLUSION:<\/jats:bold> Study findings indicate increased risks of TB development among HCPs not undergoing or not completing contact investigations and underscore the need for interventions to improve contact investigation participation and\n completeness.<\/jats:p>","DOI":"10.5588\/ijtld.21.0466","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T04:31:33Z","timestamp":1643344293000},"page":"111-118","source":"Crossref","is-referenced-by-count":0,"title":["Incomplete contact investigation and risk of developing TB among healthcare professionals"],"prefix":"10.5588","volume":"26","author":[{"given":"T.","family":"Khawcharoenporn","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Thammasat University, Pathumthani, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Noisang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2022\/00000026\/00000002\/art00008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T04:34:37Z","timestamp":1643776477000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.21.0466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2,1]]}},"alternative-id":["1027-3719(20220201)26:2L.111;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.21.0466","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2,1]]}}}