{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T18:10:42Z","timestamp":1769883042117,"version":"3.49.0"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2022,3,1]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Brooklyn Chest Hospital (BCH) is a specialised TB hospital in Cape Town, South Africa. We describe reasons for admission, patient profiles and hospital-discharge outcomes in children admitted to BCH. This was compared to a previous study (2000\u20132001).<jats:bold>METHODS:<\/jats:bold>\n This retrospective, descriptive study included all children (0\u201314 years) admitted to BCH from January 2016 to December 2017. Data collected from patient folders and a laboratory database included demographic data, reasons for admission, clinical data and hospital outcomes.<jats:bold>RESULTS:<\/jats:bold>\n Of 263 children admitted, 133 (50.6%) were male. The median age was 32 months (IQR 15\u201375); 48 (18.3%) were HIV-positive and 150 (57.0%) had bacteriologically confirmed TB. Reasons for admission included social\/caregiver-related (<jats:italic>n<\/jats:italic> = 119, 45.2%), drug-resistant TB (<jats:italic>n<\/jats:italic> = 114,\n 43.3%), TB meningitis (<jats:italic>n<\/jats:italic> = 86, 32.7%) and other severe types of TB (<jats:italic>n<\/jats:italic> = 63, 24.0%); 110 (41.8%) children had &gt;1 reason for admission. TB meningitis admissions decreased (<jats:italic>P<\/jats:italic> = 0.014) and those for drug-resistant TB increased (<jats:italic>P<\/jats:italic> &lt; 0.001) compared to 2000\u20132001.\n Pulmonary TB was diagnosed in 234 (89.0%), extrapulmonary TB in 149 (56.7%) and 126 (47.9%) had both. At discharge, 73 (27.8%) had completed treatment, 182 (69.2%) were transferred out to complete treatment at community clinics, and 6 (2.3%) died.<jats:bold>CONCLUSIONS:<\/jats:bold> Although most children\n were admitted for clinical reasons, social\/caregiver-related reasons were also important.<\/jats:p>","DOI":"10.5588\/ijtld.21.0538","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T04:32:33Z","timestamp":1645677153000},"page":"217-223","source":"Crossref","is-referenced-by-count":7,"title":["Paediatric admissions to a TB hospital: reasons for admission, clinical profile and outcomes"],"prefix":"10.5588","volume":"26","author":[{"given":"H. K.","family":"Musonda","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Child Health, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. C.","family":"Rose","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Child Health, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Switala","sequence":"additional","affiliation":[{"name":"Brooklyn Chest Hospital, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. S.","family":"Schaaf","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Child Health, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa, Brooklyn Chest Hospital, Cape Town, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2022\/00000026\/00000003\/art00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T04:34:04Z","timestamp":1652848444000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.21.0538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3,1]]}},"alternative-id":["1027-3719(20220301)26:3L.217;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.21.0538","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3,1]]}}}