{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T04:33:00Z","timestamp":1687667580665},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2023,7,1]]},"abstract":"<jats:p><jats:bold>BACKGROUND:<\/jats:bold> Early identification of TB cases, followed by treatment to completion, are essential for controlling and preventing the disease. Previous studies have found some factors associated with both loss to follow-up (LTFU) and patient delay. We aim to build a causal model\n to investigate the association between TB patient delay and LTFU.<jats:bold>METHODS:<\/jats:bold> Pulmonary TB cases were identified using the national surveillance system in Portugal between 2008 and 2017. A directed acyclic graph was used to identify the minimal set of variables to adjust for when studying\n the association between delay (exposure) and LTFU (outcome). Crude and adjusted hazard were estimated using Cox regression.<jats:bold>RESULTS:<\/jats:bold> Nearly 4% of the patients did not follow up treatment. There was no association between patient delay and LTFU, even after adjustment with the minimal\n set of covariates. Factors associated with a higher risk of LTFU were being younger, being unemployed, living in urban areas, having HIV and the abuse of alcohol and drugs.<jats:bold>CONCLUSION:<\/jats:bold> Patient delay was not associated with LTFU, while social conditions were. Future research should\n investigate the underlying reasons why patients discontinue TB treatment and use these findings to develop targeted interventions that can support patients in completing their treatment regimen.<\/jats:p>","DOI":"10.5588\/ijtld.22.0623","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T04:42:37Z","timestamp":1687581757000},"page":"537-542","source":"Crossref","is-referenced-by-count":0,"title":["The effect of TB patient delay on loss to follow-up in Portugal"],"prefix":"10.5588","volume":"27","author":[{"given":"J.","family":"Marques","sequence":"first","affiliation":[{"name":"Public Health Research Centre, Universidade NOVA de Lisboa, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. V.","family":"Rocha","sequence":"additional","affiliation":[{"name":"Public Health Research Centre, Universidade NOVA de Lisboa, Lisbon, Portugal, Comprehensive Health Research Centre, NOVA National School of Public Health, Universidade NOVA de Lisboa, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Soares","sequence":"additional","affiliation":[{"name":"Public Health Research Centre, Universidade NOVA de Lisboa, Lisbon, Portugal, Comprehensive Health Research Centre, NOVA National School of Public Health, Universidade NOVA de Lisboa, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Leite","sequence":"additional","affiliation":[{"name":"Public Health Research Centre, Universidade NOVA de Lisboa, Lisbon, Portugal, Comprehensive Health Research Centre, NOVA National School of Public Health, Universidade NOVA de Lisboa, Lisbon, Portugal, Department of Epidemiology, Instituto Nacional\n de Sa\u00fade Doutor Ricardo Jorge, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Duarte","sequence":"additional","affiliation":[{"name":"EPIUnit, Instituto de Sa\u00fade P\u00fablica, Universidade do Porto, Porto, Portugal, Laborat\u00f3rio para a Investiga\u00e7\u00e3o Integrativa e Translacional em Sa\u00fade Populacional (ITR), Porto, Portugal, Unidade de Investiga\u00e7\u00e3o\n Cl\u00ednica da ARS Norte, Porto, Portugal, Instituto de Ci\u00eancias Biom\u00e9dicas Abel Salazar, Universidade do Porto, Porto, Portugal, Servi\u00e7o de Pneumologia, Centro Hospitalar de Vila Nova de Gaia\/Espinho, Vila Nova de Gaia, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Nunes","sequence":"additional","affiliation":[{"name":"Public Health Research Centre, Universidade NOVA de Lisboa, Lisbon, Portugal, Comprehensive Health Research Centre, NOVA National School of Public Health, Universidade NOVA de Lisboa, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2023\/00000027\/00000007\/art00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T04:42:43Z","timestamp":1687581763000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.22.0623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,1]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7,1]]}},"alternative-id":["1027-3719(20230701)27:7L.537;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.22.0623","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7,1]]}}}