{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:14:54Z","timestamp":1720138494836},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:p>&lt;sec&gt;&lt;title&gt;SETTING&lt;\/title&gt;This was a retrospective chart review in Western Australia, Australia.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;OBJECTIVE&lt;\/title&gt;To describe the diagnosis, management, and treatment outcomes of ocular TB in Western Australia (WA).&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;DESIGN&lt;\/title&gt;This\n was a retrospective review of ocular TB cases in WA from 2007 to 2018 with a minimum 2-year follow-up upon completion of anti-TB therapy (ATT).&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;RESULTS&lt;\/title&gt;A total of 44 patients were referred to WA TB clinic. Ten were excluded from the analysis\n of treatment response; 34 met the inclusion criteria, of whom 97.1% were born overseas. No patients had symptomatic extraocular TB. Chest X-ray showed prior pulmonary TB in 11.7% of patients (<jats:italic>n<\/jats:italic> = 4). All patients were treated with three or four ATT drugs. The most common ocular TB manifestation\n was retinal vasculitis (23.5%). Full resolution of ocular inflammation following ATT occurred in 66.7% (<jats:italic>n<\/jats:italic> = 22), and reduced ocular inflammation requiring only topical steroid treatment was seen in 21.2% (<jats:italic>n<\/jats:italic> = 7). Treatment failure occurred in 12.1% (<jats:italic>n<\/jats:italic> = 4). Side effects\n were reported in 45.6% of patients, with gastrointestinal symptoms most common (27.2%).&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;CONCLUSION&lt;\/title&gt;Our study is the first Australian study examining the management of ocular TB. Our study highlights the challenges in diagnosing TB ocular\n disease in a low-endemicity setting and the importance of the collaboration between uveitis and TB subspecialists.&lt;\/sec&gt;<\/jats:p>","DOI":"10.5588\/ijtld.23.0353","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T04:40:17Z","timestamp":1720068017000},"page":"322-327","source":"Crossref","is-referenced-by-count":0,"title":["Ocular TB in Western Australia"],"prefix":"10.5588","volume":"28","author":[{"given":"M.","family":"Suo","sequence":"first","affiliation":[{"name":"Departments of Neurology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.K.","family":"Kenworthy","sequence":"additional","affiliation":[{"name":"Ophthalmology, Royal Perth Hospital, Perth, WA, Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, WA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Richards","sequence":"additional","affiliation":[{"name":"Ophthalmology, Royal Perth Hospital, Perth, WA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.L.","family":"Tay-Kearney","sequence":"additional","affiliation":[{"name":"Ophthalmology, Royal Perth Hospital, Perth, WA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Farah","sequence":"additional","affiliation":[{"name":"WA TB Control Program, Perth, WA,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Perera","sequence":"additional","affiliation":[{"name":"WA TB Control Program, Perth, WA, Respiratory Medicine, Royal Perth Hospital, Perth, WA, School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2024\/00000028\/00000007\/art00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T04:40:24Z","timestamp":1720068024000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.23.0353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7,1]]}},"alternative-id":["1027-3719(20240701)28:7L.322;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.23.0353","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7,1]]}}}