{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T08:21:17Z","timestamp":1774340477189,"version":"3.50.1"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2025,8,29]]},"abstract":"<jats:p>&lt;sec&gt;&lt;title&gt;OBJECTIVE&lt;\/title&gt;This study aimed to evaluate the performance of adjunctive resectional lung surgery for patients with drug-resistant TB (DR-TB).&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;METHODS&lt;\/title&gt;From January 2015 to January 2019, 40 consecutive\n pulmonary resections were performed for DR-TB patients at Wuhan Jinyintan Hospital. Clinical outcomes of extensively drug-resistant TB (XDR-TB), multidrug-resistant TB (MDR-TB), and rifampin-resistant TB (RR-TB) were analysed with a minimum of 5 years of postoperative follow-up.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;RESULTS&lt;\/title&gt;The\n mean age of the patients was 32.28 \u00b1 11.79 years, with 62.3% being female. Seven patients (17.5%) had RR-TB, 23 (57.5%) had MDR-TB, and 10 (25.0%) had XDR-TB, all of whom received second-line anti-TB drugs. Thirty patients (75.0%) presented with solitary lung cavities, 7 (17.5%) had\n multiple lung cavities, and 3 (7.5%) had destructive lung disease. Surgical interventions included lobectomy (25, 62.5%) and pneumonectomy (6, 15.0%), with a low complication rate of 12.5%. Postoperatively, 89.5% of the patients achieved sputum smear conversion, and 91.3% achieved culture\n conversion. The overall cure and survival rates were both 97.5%. The mean follow-up duration was 7.1 years.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;CONCLUSION&lt;\/title&gt;Our data indicate that adjunctive resectional lung surgery is a feasible therapeutic option for RR\/MDR\/XDR-TB patients,\n with subsequent second-line drug therapy playing a crucial role in determining the final clinical outcomes.&lt;\/sec&gt;<\/jats:p>","DOI":"10.5588\/ijtld.24.0116","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T04:35:43Z","timestamp":1756528543000},"page":"397-403","source":"Crossref","is-referenced-by-count":1,"title":["Clinical outcomes for drug-resistant TB patients after adjunctive resectional lung surgery"],"prefix":"10.5588","volume":"29","author":[{"given":"M.","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Ni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2025\/00000029\/00000009\/art00003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T04:35:45Z","timestamp":1756528545000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.24.0116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,29]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,8,29]]}},"alternative-id":["1027-3719(20250829)29:9L.397;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.24.0116","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,29]]}}}