{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T12:13:14Z","timestamp":1792498394838,"version":"4.5.0"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<sec><title>BACKGROUND<\/title>This study aimed to investigate the overall prognostic performance of the DECAF (dyspnoea, eosinopenia, consolidation, acidaemia, atrial fibrillation) score for in-hospital death in patients with acute exacerbation of chronic obstructive\n pulmonary disease (AECOPD) through a retrospective cohort study and an updated meta-analysis.<\/sec><sec><title>METHODS<\/title>Sensitivity, specificity, and predictive performance of DECAF were analysed, using receiver operating characteristic (ROC) curves and\n area under the curve (AUC) as criteria for accuracy. A literature search was performed in databases. The summary ROC (SROC) curve was used to assess the overall performance of the DECAF score.<\/sec><sec><title>RESULTS<\/title>Twenty-three non-survivors and 292\n survivors of AECOPD were included. At a cut-off value of 1.5, DECAF scores showed good sensitivity (78.3%), low specificity (55.1%), and AUC (0.719, 95% CI 0.614\u20130.824). Additionally, 22 studies (including our study) with 824 non-survivors and 8,957 survivors were included in this meta-analysis.\n The summary estimates were listed as follows: sensitivity 0.77 (95% CI 0.69\u20130.83); specificity 0.76 (95% CI 0.67\u20130.85); positive likelihood ratio 3.2 (95% CI 2.4\u20134.3); negative likelihood ratio 0.31 (95% CI 0.23\u20130.40); and diagnostic odds ratio 10.00 (95% CI 7\u201316).\n The AUC was 0.83 (95% CI 0.79\u20130.86).<\/sec><sec><title>CONCLUSIONS<\/title>The DECAF score is a simple tool to predict mortality in hospitalised patients with AECOPD, and the results of this study should be further validated.<\/sec><\/jats:p>","DOI":"10.5588\/ijtld.24.0252","type":"journal-article","created":{"date-parts":[[2024,11,23]],"date-time":"2024-11-23T04:33:26Z","timestamp":1732336406000},"page":"564-571","source":"Crossref","is-referenced-by-count":4,"title":["Performance of the DECAF score in predicting hospital mortality due to acute exacerbations of COPD"],"prefix":"10.5588","volume":"28","author":[{"given":"X.","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China;, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China;, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China;, Department of Pulmonary\n and Critical Care Medicine, The People\u2019s Hospital of Luojiang, Deyang, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China;, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China;, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China;, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China;, Department of Tuberculosis,\n The Third People\u2019s Hospital of Tibet Autonomous Region, Lhasa, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China;, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China;, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2024\/00000028\/00000012\/art00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,23]],"date-time":"2024-11-23T04:33:30Z","timestamp":1732336410000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.24.0252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,1]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12,1]]}},"alternative-id":["1027-3719(20241201)28:12L.564;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.24.0252","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12,1]]}}}