{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:53:04Z","timestamp":1787755984228,"version":"build-2784847793"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2025,5,30]]},"abstract":"<jats:p>Lung cancer and TB pose significant global health challenges, especially in low- and middle-income countries (LMICs), where they contribute significantly to morbidity and mortality rates, partly due to high smoking prevalence and delays in diagnosis and treatment. Understanding the\n association between lung cancer and TB is paramount, as it profoundly affects clinical outcomes and treatment approaches. This review examines the complex relationship between the two conditions, synthesizing findings from 20 studies retrieved through a PubMed search. Individuals with a history\n of TB disease or TB infection face an elevated risk of developing lung cancer, whereas lung cancer can negatively affect TB prognosis and treatment outcomes. We provide updated insights on the mechanisms underlying this association, and the risk factors for these conditions, to guide future\n research and enhance clinical management strategies, particularly in LMICs.<\/jats:p>","DOI":"10.5588\/ijtld.24.0491","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T04:30:46Z","timestamp":1749616246000},"page":"243-252","source":"Crossref","is-referenced-by-count":2,"title":["The interplay between TB and lung cancer: risk, prognosis and treatment dynamics"],"prefix":"10.5588","volume":"29","author":[{"given":"N.N","family":"Afifah","sequence":"first","affiliation":[{"name":"Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, Indonesia;, Department of Pharmacy, Faculty of Health Sciences, Universitas Esa Unggul, Jakarta, Indonesia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Intania","sequence":"additional","affiliation":[{"name":"Dr. H. A. Rotinsulu Lung Hospital, Bandung, Indonesia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Wijaya","sequence":"additional","affiliation":[{"name":"Division of Hematology and Medical Oncology, Department of Internal Medicine, Hasan Sadikin General Hospital, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Obinata","sequence":"additional","affiliation":[{"name":"Education and Research Support Center, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.I.","family":"Barliana","sequence":"additional","affiliation":[{"name":"Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, Indonesia;, Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Jatinangor, Indonesia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2025\/00000029\/00000006\/art00001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T04:30:48Z","timestamp":1749616248000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.24.0491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,30]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,5,30]]}},"alternative-id":["1027-3719(20250530)29:6L.243;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.24.0491","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,30]]}}}