{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T04:33:50Z","timestamp":1767414830505,"version":"3.48.0"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2026,1,2]]},"abstract":"<jats:p>&lt;sec&gt;&lt;title&gt;BACKGROUND&lt;\/title&gt;This study aimed to explore the factors associated with TB preventive therapy (TPT) uptake among household contacts of TB patients in the southern region of Bangladesh, a high-TB-burden country.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;METHODS&lt;\/title&gt;This\n cross-sectional study was conducted among household contacts of pulmonary TB cases who were eligible for TPT in Khulna District, Bangladesh, between September and October 2023. A total of 378 participants were selected randomly from six organisations providing Directly Observed Therapy Short-course\n (DOTS) services, using DOTS centre record books. Data were collected through face-to-face interviews using a pretested semi-structured questionnaire digitised in Kobo Toolbox.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;RESULTS&lt;\/title&gt;Among the participants, 64.8% had initiated TPT. Age\n above 16 years (adjusted odds ratio [aOR]: 3.61, 95% confidence interval [CI]: 1.88\u20137.02), education level of SSC and above (aOR: 4.27, 95% CI: 2.36\u20137.87), knowledge about TPT (aOR: 2.55, 95% CI: 1.27\u20135.13), and receiving TPT counselling (aOR: 16.3, 95% CI: 4.03\u2013112.0)\n emerged as strong positive predictors of TPT uptake. Urban residence showed lower odds (aOR: 0.25, 95% CI: 0.09\u20130.59) compared to semi-urban areas. The primary barriers to TPT uptake were fear of side effects (40.6%), drug unavailability (36.1%), and lack of interest (29.3%).&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;CONCLUSION&lt;\/title&gt;Successful\n TPT implementation requires strengthening health communication, ensuring drug availability, and addressing socio-economic barriers, particularly in urban areas.&lt;\/sec&gt;<\/jats:p>","DOI":"10.5588\/ijtld.25.0187","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T04:30:27Z","timestamp":1767414627000},"page":"27-33","source":"Crossref","is-referenced-by-count":0,"title":["Factors associated with initiation of TB preventive therapy"],"prefix":"10.5588","volume":"30","author":[{"given":"S.","family":"Akter","sequence":"first","affiliation":[{"name":"National Institute of Preventive and Social Medicine, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.A.S.","family":"Khan","sequence":"additional","affiliation":[{"name":"National Institute of Preventive and Social Medicine, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.M.","family":"Bin Zahur","sequence":"additional","affiliation":[{"name":"National Tuberculosis Control Programme, Directorate General of Health Services, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Jahan","sequence":"additional","affiliation":[{"name":"National Institute of Preventive and Social Medicine, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"National Institute of Preventive and Social Medicine, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.M.U.H.","family":"Roman","sequence":"additional","affiliation":[{"name":"Directorate General of Health Services, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.D.","family":"Prince","sequence":"additional","affiliation":[{"name":"Directorate General of Health Services, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.R.","family":"Parvez","sequence":"additional","affiliation":[{"name":"Rajshahi Medical College, Rajshahi, Bangladesh."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.S.","family":"Flora","sequence":"additional","affiliation":[{"name":"Directorate General of Health Services, Dhaka, Bangladesh;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2026\/00000030\/00000001\/art00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T04:30:27Z","timestamp":1767414627000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.25.0187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,2]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,2]]}},"alternative-id":["1027-3719(20260102)30:1L.27;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.25.0187","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,2]]}}}