{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T11:18:57Z","timestamp":1765797537641,"version":"3.48.0"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2025,11,28]]},"abstract":"<jats:p>\n                    &lt;sec&gt;&lt;title&gt;BACKGROUND&lt;\/title&gt;Pleural TB (PTB) is treated with standard anti-TB therapy, but additional treatments may be necessary to mitigate restrictive functional sequelae (RFS). This study identifies effective adjunctive management options to prevent PTB sequelae.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;METHODS&lt;\/title&gt;We\n systematically reviewed studies from PubMed, Cochrane Library, EMBASE, CINAHL, Web of Science, and Ovid, focusing on PTB treatments like oral steroids, pleural drainage, intrapleural therapy, and pleuroscopy. Our primary goal was to assess the impact on pulmonary function test (PFT) results,\n adhering to Cochrane\u2019s synthesis without meta-analysis (SWiM) guidelines. PROSPERO registry: CRD420251047448.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;RESULTS&lt;\/title&gt;21 out of 1,110 articles met the criteria (8 randomised, 13 nonrandomised). Intrapleural fibrinolysis with urokinase\n significantly improved predicted forced vital capacity (%FVC) and delta-FVC at 6 months (%FVC increased from 62.6% to 87.2% [\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.01]; delta-FVC = +24.6%;\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.01) in free-flowing PTB effusions. No improvements were noted with oral steroids, pleural drainage yielded inconclusive\n results, and no studies examined pleuroscopy\u2019s effects on PFT. However, both latter interventions demonstrated improvement in other outcomes.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;CONCLUSION&lt;\/title&gt;Intrapleural therapies provide robust evidence against RFS in PTB; pleural\n drainage may help with dyspnoea, while further studies are needed on pleuroscopy.&lt;\/sec&gt;\n                  <\/jats:p>","DOI":"10.5588\/ijtld.25.0246","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T11:15:46Z","timestamp":1765797346000},"page":"533-540","source":"Crossref","is-referenced-by-count":0,"title":["Preventing lung function decline and pleural thickening after pleural TB: a systematic review"],"prefix":"10.5588","volume":"29","author":[{"given":"J.A.","family":"Abrego-Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Pleural Clinic, National Institute of Respiratory Diseases (INER), Mexico City, Mexico;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Gordillo-Vald\u00e9s","sequence":"additional","affiliation":[{"name":"Pleural Clinic, National Institute of Respiratory Diseases (INER), Mexico City, Mexico;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Porcel","sequence":"additional","affiliation":[{"name":"Pleural Medicine and Clinical Ultrasound Unit, Department of Internal Medicine, Arnau de Vilanova University Hospital, Lleida, Spain;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Rodr\u00edguez-Llamazares","sequence":"additional","affiliation":[{"name":"Pleural Space Clinic, Division of Respirology and Sleep Medicine, Queen\u2019s University, Kingston, ON, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2025\/00000029\/00000012\/art00003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T11:15:48Z","timestamp":1765797348000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.25.0246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,28]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,11,28]]}},"alternative-id":["1027-3719(20251128)29:12L.533;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.25.0246","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,28]]}}}