{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T05:18:30Z","timestamp":1787980710836,"version":"build-2784847793"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2026,8,28]]},"abstract":"<jats:p>&lt;sec&gt;&lt;title&gt;BACKGROUND&lt;\/title&gt;Community TB screening using chest X-ray (CXR) is recommended for high-burden settings. The sensitivity of CXR for community screening is regarded high but may be overestimated due to incorporation bias. We conducted a meta-reanalysis\n of data used to provide more accurate estimates for CXR sensitivity.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;METHODS&lt;\/title&gt;We considered 23 studies from a published systematic review and meta-analysis where participants were screened for TB using a combination of TB symptoms and\n CXR and received bacteriological sputum testing as the reference standard. We compared the sensitivity of CXR among symptom screen\u2013positive study participants to that among all study participants.&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;RESULTS&lt;\/title&gt;Twenty-one studies were\n included for the meta-reanalysis. The pooled sensitivity (95% confidence interval) of CXR among symptom screen\u2013positive participants was 86% (83%\u201390%), lower than the pooled sensitivity based on all study participants (94% [92%\u201396%]) reported in the original meta-analysis.\n The pooled difference in sensitivity between the two approaches was 6% (4%\u20138%).&lt;\/sec&gt;&lt;sec&gt;&lt;title&gt;CONCLUSION&lt;\/title&gt;The sensitivity of CXR among symptomatic participants was lower than the published sensitivity, indicating incorporation bias. The sensitivity\n among symptomatic participants should be considered the realistic maximum sensitivity for community screening; the combined sensitivity for symptomatic and asymptomatic TB is likely lower.&lt;\/sec&gt;<\/jats:p>","DOI":"10.5588\/ijtld.25.0744","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T04:30:51Z","timestamp":1787977851000},"page":"396-402","source":"Crossref","is-referenced-by-count":0,"title":["Sensitivity of chest X-ray from community screening: a meta-reanalysis of TB prevalence survey data"],"prefix":"10.5588","volume":"30","author":[{"given":"Aldomoro","family":"Burua","sequence":"first","affiliation":[{"name":"Ministry of Health, National Tuberculosis and Leprosy Program (NTLP), Kampala, Uganda;, Makerere University Lung Institute, Makerere University College of Health Sciences, Kampala, Uganda;, Department of Global Health, Amsterdam Institute\n for Global Health and Development, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deus","family":"Lukoye","sequence":"additional","affiliation":[{"name":"Ministry of Health, National Tuberculosis and Leprosy Program (NTLP), Kampala, Uganda;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Kirenga","sequence":"additional","affiliation":[{"name":"Makerere University Lung Institute, Makerere University College of Health Sciences, Kampala, Uganda;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Hermans","sequence":"additional","affiliation":[{"name":"Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands;, Centre for Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Amsterdam\n University Medical Centers, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Cobelens","sequence":"additional","affiliation":[{"name":"Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2026\/00000030\/00000009\/art00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T04:31:10Z","timestamp":1787977870000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.25.0744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,28]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,8,28]]}},"alternative-id":["1027-3719(20260828)30:9L.396;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.25.0744","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,28]]}}}