{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:59:09Z","timestamp":1790830749832,"version":"4.1.0"},"reference-count":0,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["int j tuberc lung dis"],"published-print":{"date-parts":[[2026,9,30]]},"abstract":"\n <sec><title>BACKGROUND<\/title>Childhood TB is a major cause of morbidity and mortality among children under 15, with diagnosis challenged by non-specific symptoms and paucibacillary disease. This study analysed the impact of intensified clinical interventions on\n childhood TB notification and treatment outcomes in four high-burden regions of Tanzania.<\/sec><sec><title>METHODS<\/title>The study used a retrospective pre\u2013post intervention design, analysing childhood TB data (2018\u20132023) across four regions (Katavi,\n Kigoma, Rukwa, and Songwe) to assess the impact of health care worker training and intensified clinical services. Childhood TB data were extracted from the national electronic TB and leprosy system and analysed using \u03c7\n 2<\/jats:sup>\n tests at a 0.05 significance level.<\/sec><sec><title>RESULTS<\/title>4,178\n childhood TB cases were notified across regions. A statistically significant increase was observed post-intervention (\n P<\/jats:italic>\n < 0.001). The proportion of districts that attained the national notification target (\u226515%) significantly rose from 18.2% to 81.8%. Treatment outcomes improved\n significantly across all regions (\u03c7\n 2<\/jats:sup>\n = 23.91,\n P<\/jats:italic>\n < 0.001), with treatment completion rising from 82.1% to 87.5% and mortality decreasing from 6.0% to 3.4%.<\/sec><sec><title>CONCLUSION<\/title>Implemented interventions in the regions led\n to significant improvements in childhood TB case management. Their effectiveness was demonstrated by increased use of childhood TB diagnostic methods, improved treatment outcomes, and reduced childhood TB mortality.<\/sec>\n <\/jats:p>","DOI":"10.5588\/ijtld.26.0053","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:32:57Z","timestamp":1790829177000},"page":"436-441","source":"Crossref","is-referenced-by-count":0,"title":["Improving childhood TB case notification through intensified clinical services"],"prefix":"10.5588","volume":"30","author":[{"given":"E.N.","family":"Mgeyi","sequence":"first","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mbeya, Tanzania;, Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mwanza, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.A.","family":"Swai","sequence":"additional","affiliation":[{"name":"St. John\u2019s University of Tanzania, Dodoma, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.A.","family":"Luge","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mbeya, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Kavishe","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mbeya, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.J.","family":"Gwimile","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mwanza, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.B.","family":"Komba","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mbeya, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.T.","family":"Kasambala","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mbeya, Tanzania;, Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mwanza, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.P.","family":"Mckenzie","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mbeya, Tanzania;, Department of Childhoods, Baylor College of Medicine, Houston, TX, USA;, Texas Children\u2019s Global Health Network, Houston, TX, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.W.","family":"Ketang\u2019enyi","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mwanza, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.E.","family":"Kipiki","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mwanza, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Balama","sequence":"additional","affiliation":[{"name":"Ministry of Health-National TB and Leprosy Programme (NTLP), Dodoma, Tanzania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Sililo","sequence":"additional","affiliation":[{"name":"Ministry of Health-National TB and Leprosy Programme (NTLP), Dodoma, Tanzania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Kisonga","sequence":"additional","affiliation":[{"name":"Ministry of Health-National TB and Leprosy Programme (NTLP), Dodoma, Tanzania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.G.","family":"Onduru","sequence":"additional","affiliation":[{"name":"Ministry of Health-National TB and Leprosy Programme (NTLP), Dodoma, Tanzania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.F","family":"Mwita","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mbeya, Tanzania;, Baylor College of Medicine Children\u2019s Foundation-Tanzania, Center of Excellence, Mwanza, Tanzania;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","container-title":["The International Journal of Tuberculosis and Lung Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ingentaconnect.com\/content\/iuatld\/ijtld\/2026\/00000030\/00000010\/art00002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:33:13Z","timestamp":1790829193000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ingentaconnect.com\/content\/10.5588\/ijtld.26.0053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,9,30]]}},"alternative-id":["1027-3719(20260930)30:10L.436;1-"],"URL":"https:\/\/doi.org\/10.5588\/ijtld.26.0053","relation":{},"ISSN":["1027-3719"],"issn-type":[{"value":"1027-3719","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,30]]}}}