{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T02:20:01Z","timestamp":1768530001436,"version":"3.49.0"},"reference-count":35,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJTLD Open"],"accepted":{"date-parts":[[2025,7,7]]},"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>COVID-19 self-testing can enhance early detection to prevent disease transmission. We assessed the feasibility and acceptability of COVID-19 self-testing in Ethiopia to inform the development of national self-testing guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>We conducted a mixed-methods study and invited clients presenting to health facilities with COVID-19 symptoms or considered high risk for infection for rapid antigen detection (Ag-RDT) self-testing, using nasal swabs. We described client characteristics, self-test, and survey results and used logistic regression to determine predictors for the likeliness of future self-test use. We conducted semi-structured interviews with 13 clients, 8 health workers, and 8 decision makers and used a thematic analysis approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of 359 invited clients, 338 (94.2%) accepted and performed COVID-19 self-testing. 79.9% clients experienced self-testing as very easy and 73.7% reported likeliness of future self-test use, which was predicted by higher perceived risk of infection (adjusted odds ratio [AOR]: 2.75; 95% confidence interval [CI]: 1.02\u20137.45) and higher educational level (AOR: 5.45; 95% CI: 1.94\u201315.28). Interviewees perceived self-testing acceptable and feasible if it is available, affordable, and supported by culturally and linguistically sensitive video and written instruction materials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>COVID-19 self-testing is acceptable and feasible if implementation is accompanied by educational campaigns to empower clients to conduct self-testing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5588\/ijtldopen.24.0075","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T04:34:41Z","timestamp":1763008481000},"page":"630-638","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility and acceptability of self-testing for COVID-19 in Ethiopia: a mixed-methods 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