{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T17:55:37Z","timestamp":1781546137611,"version":"3.54.5"},"reference-count":28,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJTLD Open"],"accepted":{"date-parts":[[2026,2,23]]},"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>Multidrug-resistant TB (MDR-TB) treatment remains challenging, with significant toxicity and associated hardships that undermine adherence and cure rates. Support packages may improve outcomes, but the features most valued by people with MDR-TB are unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A discrete choice experiment was performed among adults receiving MDR-TB treatment in Lusaka, Zambia. Five features (3\u20134 levels each) comprising a support package were evaluated through 12 choice tasks comparing hypothetical packages.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Among 99 participants (median age 36 years, 68.9% men, 42.4% HIV-positive), material support was the most valued feature (relative importance [RI] = 45.7%), with transport vouchers plus food assistance being the most preferred option. Visit frequency was also important (RI = 26.7%), with similar preferences for monthly and bimonthly visits. Participants preferred phone calls for visit reminders (RI = 11.8%), health care workers for emotional support (RI = 11.2%), and community-based health care workers or loved ones for treatment observation (RI = 4.7%). Three distinct preference groups were identified \u2013 all highly valued material support but varied in their preferences for other support features and their delivery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Among people with MDR-TB in Zambia, material support mechanisms and less frequent clinic visits were highly valued. Incorporating patient preferences into treatment programmes could optimise MDR-TB care and improve treatment adherence and outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5588\/ijtldopen.25.0825","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T17:26:27Z","timestamp":1781544387000},"page":"376-383","source":"Crossref","is-referenced-by-count":0,"title":["Defining person-centred treatment support for multidrug-resistant TB: a discrete choice experiment"],"prefix":"10.5588","volume":"3","author":[{"given":"M.","family":"Kagujje","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Mtumbi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Sikandangwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Shatalimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Muyoyeta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.D.","family":"Kerkhoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","published-online":{"date-parts":[[2026,6,1]]},"reference":[{"key":"2026061510261914000_3.6.376.1","unstructured":"World Health Organization . Global Tuberculosis Report 2025. Geneva: WHO, 2025."},{"key":"2026061510261914000_3.6.376.2","unstructured":"World Health Organization . WHO operational handbook on tuberculosis. Module 4: treatment and care. 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