{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:50:26Z","timestamp":1791953426603,"version":"4.3.4"},"reference-count":27,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IJTLD Open"],"accepted":{"date-parts":[[2026,6,10]]},"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>One third of India\u2019s population has TB infection (TBI) with 10% at risk of developing TB disease. A multi-centric TBI initiative for household contacts (HHCs) of people with pulmonary TB (PTB) was implemented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The project Joint Effort for Elimination of TB was implemented in collaboration with India\u2019s National TB Elimination Programme from April 2021 to March 2024. This included doorstep ruling out of TB disease, screening HHCs for TBI, provision of TB preventive treatment (TPT), and adverse events management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of the 151,890 notified patients with PTB, 138,812 (91%) could be contacted. Of these, 112,687 (74%) consented to home visits and 94,621 (63%) households were visited. During the visits, 403,923 HHCs were identified, of whom 398,822 (99%) were screened for TBI; 310,605 (77%) consented and 253,885 (63%) initiated on TPT. Adverse events were reported by 3% HHCs with no serious episodes. Of the eligible 148,715 HHCs on TPT, 130,304 (88%) completed with an increasing trend in the TPT completion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>This community-based model for TBI management is feasible and effective. High screening and treatment completion rates alongside minimal adverse events prove this strategy is scalable and replicable for other high-burden settings worldwide.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5588\/ijtldopen.26.0237","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:29:57Z","timestamp":1791952197000},"page":"640-646","source":"Crossref","is-referenced-by-count":0,"title":["Managing TB infection among household contacts of patients with pulmonary TB"],"prefix":"10.5588","volume":"3","author":[{"given":"A.","family":"Kalra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.S.","family":"ThekkePurakkal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Showket","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Raj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Prakash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Dasari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Solanki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Dhawan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Yassin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.S.","family":"Chadha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.B.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"2026101321294884000_3.10.640.1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00655-2019"},{"key":"2026101321294884000_3.10.640.2","unstructured":"World Health Organization . Latent tuberculosis infection: updated and consolidated guidelines for programmatic management; Report No.: 9241550236. Geneva: WHO, 2018."},{"key":"2026101321294884000_3.10.640.3","unstructured":"World Health Organization . Guidelines on the management of latent tuberculosis infection. Geneva: WHO, 2015."},{"issue":"7","key":"2026101321294884000_3.10.640.4","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3390\/tropicalmed8070332","article-title":"Contact tracing and tuberculosis preventive therapy for household child contacts of pulmonary tuberculosis patients in the Kyrgyz Republic: how well are we doing?","volume":"8","author":"Kadyrov","year":"2023","journal-title":"Trop Med Infect Dis"},{"key":"2026101321294884000_3.10.640.5","unstructured":"World Health Organization . Implementing the end TB strategy: the essentials. Geneva: World Health Organization, 2015."},{"key":"2026101321294884000_3.10.640.6","unstructured":"World Health Organization . Global tuberculosis report 2023. 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India TB report 2024. New Delhi, India: Ministry of Health and Family Welfare, 2024."},{"key":"2026101321294884000_3.10.640.13","doi-asserted-by":"publisher","DOI":"10.4103\/IJMR.IJMR_382_23"},{"key":"2026101321294884000_3.10.640.14","unstructured":"Central TB Division . National strategic plan to end tuberculosis in India 2020-25: National TB Elimination Programme. New Delhi, India: Ministry of Health and Family Welfare, 2020."},{"key":"2026101321294884000_3.10.640.15","unstructured":"Central TB Division . Guidelines for programmatic management of tuberculosis preventive treatment in India: National TB Elimination Programme. New Delhi, India: Ministry of Health and Family Welfare, 2021."},{"key":"2026101321294884000_3.10.640.16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0236743"},{"issue":"1","key":"2026101321294884000_3.10.640.17","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3390\/tropicalmed9010007","article-title":"Test and treat model for tuberculosis preventive treatment among household contacts of pulmonary tuberculosis patients in selected districts of Maharashtra: a mixed-methods study on care cascade, timeliness, and early implementation challenges","volume":"9","author":"Mahajan","year":"2023","journal-title":"Trop Med Infect Dis"},{"issue":"1","key":"2026101321294884000_3.10.640.18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3390\/tropicalmed9010024","article-title":"Situation analysis of early implementation of programmatic management of tuberculosis preventive treatment among household contacts of pulmonary TB patients in Delhi, India","volume":"9","author":"Alvi","year":"2024","journal-title":"Trop. 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