{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T03:34:14Z","timestamp":1791776054384,"version":"4.3.4"},"reference-count":1,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"Supplement 1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["public health action"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>\n                    <jats:bold>SETTING:<\/jats:bold>\n                    Patan Hospital, Lalitpur, Nepal.\n                    <jats:bold>OBJECTIVES:<\/jats:bold>\n                    To describe 1) the prevalence of methicillin-resistant\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    (MRSA) and its antibiotic sensitivity pattern; 2) the demographic and clinical characteristics associated with MRSA infections; and 3) the treatment outcomes of in-patients with MRSA infection among patients with\n                    <jats:italic>S. aureus<\/jats:italic>\n                    infection between January 2018 and December 2020.\n                    <jats:bold>DESIGN:<\/jats:bold>\n                    This was a cross-sectional study using electronic and paper-based hospital records of patients with\n                    <jats:italic>S. aureus<\/jats:italic>\n                    infection.\n                    <jats:bold>RESULTS:<\/jats:bold>\n                    Of the 1,804 patients with\n                    <jats:italic>S. aureus<\/jats:italic>\n                    infection\n                    <jats:italic>,<\/jats:italic>\n                    1,027 patients (57%, 95% CI 55\u201359) had MRSA. The MRSA were susceptible to vancomycin (100%), linezolid (96%), doxycycline (96%), chloramphenicol (86%) and cotrimoxazole (70%), and resistant to erythromycin (68%), clindamycin (56%), gentamycin (58%), ciprofloxacin (92%) and ofloxacin (91%). The prevalence of MRSA was higher in 2019, among out-patients, and in respiratory samples, and lower in blood samples. Of the 142 in-patients with MRSA, 93% had a successful clinical outcome (cured\/improved).\n                    <jats:bold>CONCLUSION:<\/jats:bold>\n                    More than 50% of patients with\n                    <jats:italic>S. aureus<\/jats:italic>\n                    infection had MRSA that were resistant to commonly available antibiotics. This calls for strengthening surveil-lance and good infection control practices in this hospital.\n                  <\/jats:p>","DOI":"10.5588\/pha.21.0042","type":"journal-article","created":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T23:47:33Z","timestamp":1636415253000},"page":"46-51","source":"Crossref","is-referenced-by-count":19,"title":["Prevalence of methicillin-resistant\n                    <i>Staphylococcus aureus<\/i>\n                    in a tertiary hospital in Nepal"],"prefix":"10.5588","volume":"11","author":[{"given":"P.","family":"Pradhan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Rajbhandari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. B.","family":"Nagaraja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Shrestha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Grigoryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Satyanarayana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Davtyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3554","published-online":{"date-parts":[[2021,11,1]]},"reference":[{"key":"R50_437_576","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ijid.2020.11.152","volume":"103","year":"2021","journal-title":"Int J Infect Dis","ISSN":"https:\/\/id.crossref.org\/issn\/1201-9712","issn-type":"print"}],"container-title":["Public Health Action"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.5588\/pha.21.0042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T17:20:17Z","timestamp":1768411217000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.theunion.org\/lookup\/doi\/10.5588\/pha.21.0042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":1,"journal-issue":{"issue":"Supplement 1","published-online":{"date-parts":[[2021,11,1]]},"published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.5588\/pha.21.0042"],"URL":"https:\/\/doi.org\/10.5588\/pha.21.0042","relation":{},"ISSN":["2220-8372"],"issn-type":[{"value":"2220-8372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11]]}}}