{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T18:09:43Z","timestamp":1779127783560,"version":"3.51.4"},"reference-count":10,"publisher":"International Union Against Tuberculosis and Lung Disease","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["public health action"],"accepted":{"date-parts":[[2026,3,16]]},"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>In 2023, Sierra Leone started tuberculosis preventive therapy (TPT) implementation. The tuberculosis programme recommends four contacts per index case for tracing and screening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>This study was to assess the performance of early implementation of contact tracing, screening, and TPT uptake in five regional hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>Of 905 index cases recorded, 1,222 contacts were traced and screened by community health workers. Of these, 433 were enrolled into TPT, and 353 (82%) completed the TPT regimen. Eighty out of 353 (18%) on TPT were lost to follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>Deficiencies in documenting contacts and logistical constraints to trace, screen, and follow up for enrolment and completion of TPT need to be addressed for TPT scale-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.5588\/pha.26.0005","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T17:42:47Z","timestamp":1779126167000},"page":"117-120","source":"Crossref","is-referenced-by-count":0,"title":["Tuberculosis preventive therapy in Sierra Leone: early implementation gaps and lessons learned"],"prefix":"10.5588","volume":"16","author":[{"given":"L.","family":"Farma-Grant","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.S.","family":"Kanu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Molleh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.F.","family":"Kamara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.R.Y.","family":"Kamara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Sesay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.K.","family":"Lahai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Fofanah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.-A.","family":"Falama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.K.","family":"Offe Amponsah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mahmoud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.S.","family":"Grant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Siatty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Zachariah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Koroma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mustapha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Sesay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Kenneh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3554","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"2026051810424193000_16.2.117.1","unstructured":"World Health Organisation . Global tuberculosis report 2023. Geneva: WHO, 2023."},{"issue":"5","key":"2026051810424193000_16.2.117.2","doi-asserted-by":"crossref","first-page":"E194","DOI":"10.1097\/INF.0000000000003505","article-title":"High prevalence of tuberculosis infection and disease in child household contacts of adults with rifampin-resistant tuberculosis","volume":"41","author":"Kim","year":"2022","journal-title":"Pediatr Infect Dis J"},{"key":"2026051810424193000_16.2.117.3","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03028-2020"},{"key":"2026051810424193000_16.2.117.4","unstructured":"Hopewell PC , Elizabeth F , Miller C . Recommendations for investigating contacts of persons with infectious tuberculosis in low- and middle-Income countries. Geneva: WHO, 2012."},{"issue":"7","key":"2026051810424193000_16.2.117.5","first-page":"332","article-title":"Contact tracing and tuberculosis preventive therapy for household child contacts of pulmonary tuberculosis patients in the Kyrgyz Republic: how well are we doing?","volume":"8","author":"Kadyrov","year":"2023","journal-title":"Trop Med Infect Dis"},{"key":"2026051810424193000_16.2.117.6","unstructured":"Sierra Leone Ministry of Health . FINAL Sierra Leone NSP 2021-2025_TB strategy [Internet]. Freetown, Sierra Leone: Sierra Leone Ministry of Health, 2020. https:\/\/mohs.gov.sl\/policy-documents (Accessed 10 November 2025)."},{"key":"2026051810424193000_16.2.117.7","unstructured":"Ministry of Health, Sierra Leone. Ministry of Health, National Leprosy and Tuberculosis Control Programme, National Guidelines for Clinical and Programmatic Management of TB in Sierra Leone. Freetown, Sierra Leone: Ministry of Health, 2024."},{"key":"2026051810424193000_16.2.117.8","unstructured":"Ministry of Health, Sierra Leone . Ministry of Health and Sanitation, The Republic of Sierra Leone, End-term review report of the national strategic plan for tuberculosis and leprosy (2021-2025). Freetown, Sierra Leone: Sierra Leone Ministry of Health, 2025."},{"issue":"12","key":"2026051810424193000_16.2.117.9","doi-asserted-by":"crossref","first-page":"e0295580","DOI":"10.1371\/journal.pone.0295580","article-title":"Feasibility, enablers and challenges of using timeliness metrics for household contact tracing and TB preventive therapy in Pakistan","volume":"18","author":"Jamil","year":"2023","journal-title":"PLoS One"},{"issue":"4","key":"2026051810424193000_16.2.117.10","first-page":"409","article-title":"Global evidence on risk factors for childhood tuberculosis: a scoping review","volume":"7","author":"Safira","year":"2025","journal-title":"Jambura J Health Sci Res"}],"container-title":["Public Health Action"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.5588\/pha.26.0005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T17:42:48Z","timestamp":1779126168000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.theunion.org\/lookup\/doi\/10.5588\/pha.26.0005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,5,1]]},"published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.5588\/pha.26.0005"],"URL":"https:\/\/doi.org\/10.5588\/pha.26.0005","relation":{},"ISSN":["2220-8372"],"issn-type":[{"value":"2220-8372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]}}}