{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T19:59:18Z","timestamp":1782417558988,"version":"3.54.5"},"reference-count":7,"publisher":"STEF92 Technology","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,15]]},"abstract":"<jats:p>Cyclophosphamide (CP) is a cytostatic drug prescribed at large scale, which proved to induce toxic effect on ecosystems and cannot be removed by conventional wastewater treatment processes. Therefore, there is a need to test advanced degradation processes for its removal from wastewater discharges. CP photocatalytic degradation via UV-VIS irradiation was studied using a Nitrogen -doped TiO2 catalyst. The catalyst was synthesized as thin film deposited on glass substrate under nitrogen atmosphere technique. The influence of N2 flow rate and annealing temperature on the CP degradation efficiency was investigated and best photocatalytic activity was obtained for catalyst with 1.8 %wt nitrogen content, synthesized at N2 flow rate=10 sccm, annealed at 550 oC for 1 hour. Its use assure the CP degradation with a pseudo-first order rate constant of 5.262 x 10-4 s-1 and an efficiency of 98 % for an irradiation time of 120. Based on the obtained experimental results in the presence of various scavengers it was found that superoxide radicals are representing the main oxidizing reactive specie involved in CP degradation, but contribution of free hydroxyl radicals from bulk solution is also possible. Degradation intermediates were identified using LC-MS and a possible degradation pathway consisting in three conversion routes was proposed.<\/jats:p>","DOI":"10.5593\/sgem2022\/5.1\/s20.065","type":"proceedings-article","created":{"date-parts":[[2023,2,18]],"date-time":"2023-02-18T11:59:41Z","timestamp":1676721581000},"page":"513-520","source":"Crossref","is-referenced-by-count":1,"title":["UV-VIS PHOTOCATALYTIC DEGRADATION OF CYCLOPHOSPHAMIDE ON NITROGEN DOPED TIO2 THIN FILM. KINETICS AND POSSIBLE DEGRADATION PATHWAY"],"prefix":"10.5593","volume":"22","author":[{"given":"Mirela Alina","family":"Constantin","sequence":"first","affiliation":[{"name":"National Research and Development Institute for Industrial Ecology - ECOIND","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucian-Alexandru","family":"Constantin","sequence":"additional","affiliation":[{"name":"National Research and Development Institute for Industrial Ecology - ECOIND","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arcadie","family":"Sobetkii","sequence":"additional","affiliation":[{"name":"SC.MGM STAR CONSTRUCT S.R.L","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florentina Laura","family":"Chiriac","sequence":"additional","affiliation":[{"name":"National Research and Development Institute for Industrial Ecology - ECOIND","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolae Ionut","family":"Cristea","sequence":"additional","affiliation":[{"name":"National Research and Development Institute for Industrial Ecology - ECOIND","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3602","reference":[{"key":"ref=1","doi-asserted-by":"crossref","unstructured":"[1] Nitoi I, Oancea P, Raileanu M, Crisan M, Constantin L, Cristea I., UV\ufffdVIS photocatalytic degradation of nitrobenzene from water using heavy metal doped titania, Journal of Industrial and Engineering Chemistry, vol 21, pp 677-682, 2015.","DOI":"10.1016\/j.jiec.2014.03.036"},{"key":"ref=2","doi-asserted-by":"crossref","unstructured":"[2] Sato S, Nakamura R, Abe S., Visible-light sensitization of TiO2 photocatalysts by wet-method N doping, Applied Catalysis A: General, vol 284\/issues 1-2, pp 131-137, 2005.","DOI":"10.1016\/j.apcata.2005.01.028"},{"key":"ref=3","doi-asserted-by":"crossref","unstructured":"[3] Nosaka Y, Matsushita M, Nishino J, Nosaka AY., Nitrogen-doped titanium dioxide photocatalysts for visible response prepared by using organic compounds, Science and Technology of Advanced Materials, vol 6\/issue 2, pp 143-148, 2005.","DOI":"10.1016\/j.stam.2004.11.006"},{"key":"ref=4","doi-asserted-by":"crossref","unstructured":"[4] Irie H, Watanabe Y, Hashimoto K., Nitrogen-concentration dependence on photocatalytic activity of TiO2-xNx powders, The Journal of Physical Chemistry B, vol 107\/issue 23, pp 5483-5486, 2003.","DOI":"10.1021\/jp030133h"},{"key":"ref=5","doi-asserted-by":"crossref","unstructured":"[5] Kosowska B, Mozia S, Morawski AW, Grzmil B, Janus M, Kalucki K., The preparation of TiO2\ufffdnitrogen doped by calcination of TiO2 xH2O under ammonia atmosphere for visible light photocatalysis, Solar Energy Materials & Solar Cells, vol 88\/issue 3, pp 269-280, 2005.","DOI":"10.1016\/j.solmat.2004.11.001"},{"key":"ref=6","doi-asserted-by":"crossref","unstructured":"[6] Lai WW-P, Lin HH-H, Lin AY-C., TiO2 photocatalytic degradation and transformation of oxazaphosphorine drugs in an aqueous environment, Journal of Hazardous Materials, vol 287, pp 133-141, 2015.","DOI":"10.1016\/j.jhazmat.2015.01.045"},{"key":"ref=7","doi-asserted-by":"crossref","unstructured":"[7] Wang M-C, Lin H-J, Wang C-H, Wu H-C., Effects of annealing temperature on the photocatalytic activity of N-doped TiO2 thin films, Ceramics International, vol 38\/issue 1, pp 195-200, 2012.","DOI":"10.1016\/j.ceramint.2011.05.160"}],"event":{"name":"22nd SGEM International Multidisciplinary Scientific GeoConference 2022","theme":"Earth and Planetary Sciences","location":"Albena, BG","acronym":"SGEM2022","number":"22","sponsor":["SGEM WORLD SCIENCE (SWS) Scholarly Society, Austria"],"start":{"date-parts":[[2022,7,4]]},"end":{"date-parts":[[2022,7,10]]}},"container-title":["SGEM International Multidisciplinary Scientific GeoConference\ufffd EXPO Proceedings","22nd SGEM International Multidisciplinary Scientific GeoConference Proceedings 2022"],"original-title":[],"deposited":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T19:26:02Z","timestamp":1782415562000},"score":1,"resource":{"primary":{"URL":"https:\/\/epslibrary.at\/items\/9595eb59-4f6a-455f-9923-e956a1fe3f80\/uv-vis-photocatalytic-degradation-of-cyclophosphamide-on-nitrogen-doped-tio2-thin-film-kin"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,15]]},"references-count":7,"URL":"https:\/\/doi.org\/10.5593\/sgem2022\/5.1\/s20.065","relation":{},"ISSN":["1314-2704"],"issn-type":[{"value":"1314-2704","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11,15]]}}}