{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T06:56:12Z","timestamp":1785308172976,"version":"3.55.0"},"reference-count":29,"publisher":"Polish Society of Microbiologists","issue":"3","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Four\n                    <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                    isolates from children hospitalized over 10 months in an intensive care unit in a children\u2019s teaching hospital in Poland were analyzed. All of the isolates belonged to a single pulsotype and sequence type (ST) 11, and produced the KPC-2 carbapenemase and extended-spectrum \u03b2-lactamase (ESBL) CTX-M-15. They were resistant to a variety of antimicrobials, and their \u03b2-lactam resistance patterns were typical for KPC producers. This is one of few cases of identification of KPC (or carbapenemase)-producing\n                    <jats:italic>K. pneumoniae<\/jats:italic>\n                    in a pediatric center in Poland.\n                  <\/jats:p>","DOI":"10.5604\/01.3001.0010.4884","type":"journal-article","created":{"date-parts":[[2017,9,28]],"date-time":"2017-09-28T03:42:27Z","timestamp":1506570147000},"page":"401-404","source":"Crossref","is-referenced-by-count":5,"title":["KPC-2-producing\n                    <i>Klebsiella pneumoniae<\/i>\n                    ST11 in a Children\u2019s Hospital in Poland"],"prefix":"10.33073","volume":"66","author":[{"given":"MONIKA","family":"MACHULSKA","sequence":"first","affiliation":[{"name":"Department of Molecular Microbiology , National Medicines Institute , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ANNA","family":"BARANIAK","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology , National Medicines Institute , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"IWONA","family":"\u017bAK","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology , Children\u2019s University Hospital , Krak\u00f3w , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KATARZYNA","family":"BOJARSKA","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Clinical Microbiology , The National Reference Centre for Susceptibility Testing , National Medicines Institute , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DOROTA","family":"\u017bABICKA","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Clinical Microbiology , The National Reference Centre for Susceptibility Testing , National Medicines Institute , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"IWONA","family":"SOWA-SIERANT","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology , Children\u2019s University Hospital , Krak\u00f3w , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WALERIA","family":"HRYNIEWICZ","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Clinical Microbiology , The National Reference Centre for Susceptibility Testing , National Medicines Institute , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MAREK","family":"GNIADKOWSKI","sequence":"additional","affiliation":[{"name":"Department of Molecular Microbiology , National Medicines Institute , Warsaw , Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18083","published-online":{"date-parts":[[2017,9,27]]},"reference":[{"key":"2026052913571663226_j_01.3001.0010.4884_ref_001","doi-asserted-by":"crossref","unstructured":"Andrade L.N., L. Vitali, G.G. Gaspar, F. Bellissimo-Rodrigues, R. Martinez and A.L. Darini. 2014. Expansion and evolution of a virulent, extensively drug-resistant (polymyxin B-resistant), QnrS1-, CTX-M-2-, and KPC-2-producing Klebsiella pneumoniae ST11 international high-risk clone. J. Clin. Microbiol. 52(7): 2530\u20132435.10.1128\/JCM.00088-14409769524808234","DOI":"10.1128\/JCM.00088-14"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_002","unstructured":"Baraniak A., A. Grabowska, R. Izdebski, J. Fiett, M. Herda,"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_003","doi-asserted-by":"crossref","unstructured":"K. Bojarska, D. \u017babicka, M. Kania-Pud\u0142o, G. M\u0142ynarczyk, Z. \u017bak- Pu\u0142awska and others. 2011. Molecular characteristics of KPC-pro- ducing Enterobacteriaceae at the early stage of their dissemination in Poland, 2008\u20132009. Antimicrob. Agents Chemother. 55: 5493\u20135499.","DOI":"10.1128\/AAC.05118-11"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_004","doi-asserted-by":"crossref","unstructured":"Baraniak A., R. Izdebski, J. Fiett, M. Herda, L.P. Derde, M.J. Bonten, A. Adler, Y. Carmeli, H. Goossens, W. Hryniewicz and others. 2015. KPC-like carbapenemase-producing Enterobac- teriaceae colonizing patients in Europe and Israel. Antimicrob. Agents Chemother. 28; 60(3): 1912\u20131917.","DOI":"10.1128\/AAC.02756-15"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_005","doi-asserted-by":"crossref","unstructured":"Baraniak A., R. Izdebski, J. Fiett, I. Gawryszewska, K. Bojarska, M. Herda, E. Literacka, D. \u017babicka, H. Tomczak, N. Pewi\u0144ska and others. 2016. NDM-producing Enterobacteriaceae in Poland, 2012\u20132014: inter-regional outbreak of Klebsiella pneumoniae ST11 and sporadic cases. J. Antimicrob. Chemother. 71(1): 85\u201391.","DOI":"10.1093\/jac\/dkv282"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_006","doi-asserted-by":"crossref","unstructured":"Baraniak A., R. Izdebski, M. Herda, J. Fiett, W. Hryniewicz, M. Gniadkowski, I. Kern-Zdanowicz, K. Filczak and U. \u0141opaciuk. 2009. The emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. Antimicrob. Agents Chemother. 53: 4565\u20134567.10.1128\/AAC.00436-09276419719620323","DOI":"10.1128\/AAC.00436-09"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_007","doi-asserted-by":"crossref","unstructured":"Baraniak A., R. Izdebski, D. \u017babicka, K. Bojarska, S. G\u00f3rska, E. Literacka, J. Fiett, W. Hryniewicz and M. Gniadkowski. 2017. Multiregional parallel dissemination of diverse KPC-produ- cing Klebsiella pneumoniae ST258\/ST512 genotypes in Poland, 2010\u20132014. J. Antimicrob. Chemother. 72(6): 1610\u20131616.","DOI":"10.1093\/jac\/dkx054"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_008","doi-asserted-by":"crossref","unstructured":"Bush K. 2010. Alarming \u03b2-lactamase-mediated resistance in multidrugresistant Enterobacteriaceae. Curr. Opin. Microbiol. 13: 558\u2013564.10.1016\/j.mib.2010.09.00620920882","DOI":"10.1016\/j.mib.2010.09.006"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_009","doi-asserted-by":"crossref","unstructured":"Chen L., B. Mathema, K.D. Chavda, F.R. DeLeo, R.A. Bonomo and B.N. Kreiswirth. 2014. Carbapenemase-producing Klebsiella pneumoniae: molecular and genetic decoding. Trends Microbiol. 22: 686\u2013696.10.1016\/j.tim.2014.09.003436595225304194","DOI":"10.1016\/j.tim.2014.09.003"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_010","doi-asserted-by":"crossref","unstructured":"Cheng L, X.L. Cao, Z.F. Zhang, M.Z. Ning, X.J. Xu, W. Zhou, J.H. Chen, J.H. Zhang, H. Shen and K. Zhang. 2016. Clonal dissemination of KPC-2 producing Klebsiella pneumoniae ST11 clone with high prevalence of oqxAB and rmtB in a tertiary hospital in China: results from a 3-year period. Ann. Clin. Microbiol. Anti- microb. 15: 1 (drop)10.1186\/s12941-015-0109-x471758826786830","DOI":"10.1186\/s12941-015-0109-x"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_011","doi-asserted-by":"crossref","unstructured":"Diancourt L, V. Passet, J. Verhoef, P.A. Grimont and S. Brisse. 2005. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J. Clin. Microbiol. 43: 4178\u20134182.10.1128\/JCM.43.8.4178-4182.2005123394016081970","DOI":"10.1128\/JCM.43.8.4178-4182.2005"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_012","doi-asserted-by":"crossref","unstructured":"Doi Y., B.A. Potoski, J.M. Adams-Haduch, H.E. Sidjabat, A.W. Pasculle and D.L. Paterson. 2008. Simple disk-based method for detection of Klebsiella pneumoniae carbapenemase-type \u03b2-lactamase by use of a boronic acid compound. J. Clin. Microbiol. 46: 4083\u20134086.10.1128\/JCM.01408-08259326418923005","DOI":"10.1128\/JCM.01408-08"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_013","unstructured":"Hu L., Y. Liu, L. Deng, Q. Zhong, Y. Hang, Z. Wang, L. Zhan,"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_014","unstructured":"L. Wang and F. Yu. 2016. Outbreak by ventilator-associated ST11 K. pneumoniae with co-production of CTX-M-24 and KPC-2 in a SICU of a Tertiary Teaching Hospital in Central China. Front. Microbiol. doi: 10.3389\/fmicb.2016.01190.10.3389\/fmicb.2016.01190497048727531996"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_015","unstructured":"Lopez J.A., A. Correa, S. Navon-Venezia, A.L. Correa, J.A. Torres, D.F. Brice\u00f1o, M.C. Montealegre, J.P. Quinn, Y. Carmeli and"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_016","doi-asserted-by":"crossref","unstructured":"M.V. Villegas. 2011. Intercontinental spread from Israel to Colombia of a KPC-3-producing Klebsiella pneumoniae strain. Clin. Microbiol. Infect. 17: 52\u201356.10.1111\/j.1469-0691.2010.03209.x20219078","DOI":"10.1111\/j.1469-0691.2010.03209.x"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_017","doi-asserted-by":"crossref","unstructured":"Mathers A.J., G. Peirano and J.D. Pitout. 2015.The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae. Clin. Microbiol. Rev. 28: 565\u2013591.10.1128\/CMR.00116-14440562525926236","DOI":"10.1128\/CMR.00116-14"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_018","doi-asserted-by":"crossref","unstructured":"Mehta S.C., K. Rice and T. Palzkill. 2015. Natural variants of the KPC-2 carbapenemase have evolved increased catalytic efficiency for ceftazidime hydrolysis at the cost of enzyme stability. PLoS Pathog. 11: e1004949.10.1371\/journal.ppat.1004949","DOI":"10.1371\/journal.ppat.1004949"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_019","doi-asserted-by":"crossref","unstructured":"Munoz-Price L.S., L. Poirel, R.A. Bonomo, M.J. Schwaber, G.L. Daikos, M. Cormican, G. Cornaglia, J. Garau, M. Gniadkow- ski, M.K. Hayden and others. 2013. Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. Lancet Infect. Dis. 13: 785\u2013796.10.1016\/S1473-3099(13)70190-7","DOI":"10.1016\/S1473-3099(13)70190-7"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_020","doi-asserted-by":"crossref","unstructured":"Naas T., G. Cuzon, M.V. Villegas, M.F. Lartigue, J.P. Quinn and P. Nordmann. 2008. Genetic structures at the origin of acquisition of the beta-lactamase blaKPC gene. Antimicrob. Agents Chemother. 52: 1257\u20131263.10.1128\/AAC.01451-07229252218227185","DOI":"10.1128\/AAC.01451-07"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_021","doi-asserted-by":"crossref","unstructured":"Navon-Venezia S., I. Chmelnitsky, A. Leavitt, M.J. Schwaber, D. Schwartz and Y. Carmeli. 2006. Plasmid-mediated imipenem- hydrolyzing enzyme KPC-2 among multiple carbapenem-resistant Escherichia coli clones in Israel. Antimicrob. Agents Chemother. 50: 3089\u20133101.10.1128\/AAC.00438-06156353116940107","DOI":"10.1128\/AAC.00438-06"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_022","doi-asserted-by":"crossref","unstructured":"Nordmann P. and L. Poirel. 2014. The difficult-to-control spread of carbapenemase producers among Enterobacteriaceae worldwide. Clin. Microbiol. Infect. 20: 821\u2013830.10.1111\/1469-0691.1271924930781","DOI":"10.1111\/1469-0691.12719"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_023","doi-asserted-by":"crossref","unstructured":"Nordmann P., L. Poirel and L. Dortet. 2012. Rapid detection of carbapenemase-producing Enterobacteriaceae. Emerg. Infect. Dis. 18(9): 1503\u20131507.","DOI":"10.3201\/eid1809.120355"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_024","doi-asserted-by":"crossref","unstructured":"Oteo J., M. P\u00e9rez-V\u00e1zquez, V. Bautista, A. Ortega, P. Zamarr\u00f3n, D. Saez, S. Fern\u00e1ndez-Romero, N. Lara, R. Ramiro, B. Aracil and others. 2016. The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones of Klebsiella pneumoniae ST11\/KPC-2, ST101\/KPC-2 and ST512\/KPC-3. J. Anti- microb. Chemother. 71(12): 3392\u20133399.","DOI":"10.1093\/jac\/dkw321"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_025","doi-asserted-by":"crossref","unstructured":"Paczosa M.K. and J. Mecsas. 2016. Klebsiella pneumoniae: going on the offense with a strong defense. J. Microbiol Mol. Biol. Rev. 80(3): 629\u2013661.","DOI":"10.1128\/MMBR.00078-15"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_026","doi-asserted-by":"crossref","unstructured":"Pereira P.S., C.F. de Araujo, L.M. Seki, V. Zahner, A.P. Carvalho- Assef and M.D. Asensi. 2013. Update of the molecular epidemiology of KPC-2-producing Klebsiella pneumoniae in Brazil: spread of clonal complex 11 (ST11, ST437 and ST340). J. Antimicrob. Chemo- ther. 68(2): 312\u2013316.10.1093\/jac\/dks39623070735","DOI":"10.1093\/jac\/dks396"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_027","doi-asserted-by":"crossref","unstructured":"Seifert H., L. Dolzani, R. Bressan, T. van der Reijden, B. van Strijen, D. Stefanik, H. Heersma and L. Dijkshoorn. 2005. Standardization and interlaboratory reproducibility assessment of pulsed-field gel electrophoresis-generated fingerprints of Acineto- bacter baumannii. J. Clin. Microbiol. 43: 4328\u20134335.10.1128\/JCM.43.9.4328-4335.2005123407116145073","DOI":"10.1128\/JCM.43.9.4328-4335.2005"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_028","doi-asserted-by":"crossref","unstructured":"Tumbarello M., E.M. Trecarichi, F.G. De Rosa, M. Giannella, D.R. Giacobbe, M. Bassetti, A.R. Losito, M. Bartoletti, V. Del Bono, S. Corcione and others. 2015. Infections caused by KPC-producing Klebsiella pneumoniae: differences in therapy and mortality in a multicentre study. J. Antimicrob. Chemother. 70: 2133\u20132143.10.1093\/jac\/dkv08625900159","DOI":"10.1093\/jac\/dkv086"},{"key":"2026052913571663226_j_01.3001.0010.4884_ref_029","doi-asserted-by":"crossref","unstructured":"Qi Y., Z. Wei, S. Ji, X. Du, P. Shen and Y. Yu. 2011. ST11, the dominant clone of KPC-producing Klebsiella pneumoniae in China. J. Antimicrob. Chemother. 66: 307\u2013312.","DOI":"10.1093\/jac\/dkq431"}],"container-title":["Polish Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pjm-microbiology.publisherspanel.com\/gicid\/pdf\/01.3001.0010.4884","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/reference-global.com\/pdf\/10.5604\/01.3001.0010.4884","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T14:15:34Z","timestamp":1780064134000},"score":1,"resource":{"primary":{"URL":"https:\/\/reference-global.com\/article\/10.5604\/01.3001.0010.4884"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,1]]},"references-count":29,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,9,27]]},"published-print":{"date-parts":[[2017,1,1]]}},"alternative-id":["10.5604\/01.3001.0010.4884"],"URL":"https:\/\/doi.org\/10.5604\/01.3001.0010.4884","relation":{},"ISSN":["2544-4646"],"issn-type":[{"value":"2544-4646","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,1]]}}}