{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T07:12:30Z","timestamp":1722841950686},"reference-count":21,"publisher":"Index Copernicus","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol Przegl Chir"],"published-print":{"date-parts":[[2017,10,31]]},"abstract":"<jats:p>Introduction: In the world, the inflammatory bowel disease affects an increasing number of younger and younger patients, and in some of them parenteral nutrition is an alternative to high-risk surgical intervention due to advancement of the disease and malnutrition. Aim: The aim of the study was to assess the results of home parenteral nutrition in patients with severe bowel inflammatory disease, in whom surgical treatment is associated with high risk of complications. Materials and methods: A retrospective analysis was conducted on 46 patients, who received home parenteral nutrition instead of another surgical intervention. The inclusion criteria included home parenteral nutrition and diagnosis of Crohn\u2019s disease or ulcerative colitis. Results: Mean number of complications requiring hospital admission per patient was 1.76, the BMI increased by 4.3 on average [kg\/m2]. During parenteral nutrition, the percentage of patients, in whom anti-inflammatory or immunosuppressant drugs were completely discontinued, was 17.4%. In the whole group, at least one immunosuppressive drug was discontinued in onefifth of patients. Mean albumin level increased by 2.4 g\/L, lymphocyte count dropped by 474 lymphocytes\/mm3, and leukocyte count increased by 747.6\/mm3. The patients described their condition as good in 87%, and 7.4% of patients were able to work. Conclusions: Home parenteral nutrition positively affects patient\u2019s general condition by increasing BMI and normalizing biochemical test results. The results indicate the need to consider this method as an alternative to surgical intervention in severe bowel inflammatory disease with high perioperative risk, which could reduce the complication rate.<\/jats:p>","DOI":"10.5604\/01.3001.0010.5408","type":"journal-article","created":{"date-parts":[[2018,5,22]],"date-time":"2018-05-22T09:27:34Z","timestamp":1526981254000},"page":"23-28","source":"Crossref","is-referenced-by-count":4,"title":["Results of home parenteral nutrition in patients with severe inflammatory bowel disease \u2013 an alternative for surgery of malnourished patients"],"prefix":"10.5604","volume":"89","author":[{"given":"Maryla","family":"Turkot","sequence":"first","affiliation":[{"name":"Department of General Surgery and Clinical Nutrition, Warsaw Medical University; Head: dr hab. n. med. Jacek Sobocki"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Sobocki","sequence":"additional","affiliation":[{"name":"Department of General Surgery and Clinical Nutrition, Warsaw Medical University; Head: dr hab. n. med. Jacek Sobocki"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3689","reference":[{"key":"154553r1","unstructured":"W. Bartnik, \u201eWytyczne postepowania w nieswoistyc chorobach zapalnych jelit,\u201d Przegl\u0105d Gastroenterologiczny, tom 2, nr 5, pp. 216-228, 2007."},{"key":"154553r2","unstructured":"E. Marcinkowska, \u201eJako\u015b\u0107 \u017cycia pacjent\u00f3w z nieswoistymi chorobami zapalnymi jelit w zale\u017cno\u015bci od przebiegu, aktywno\u015bci i sposobu leczenia,\u201d Praca Doktorska, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Pozna\u0144, 2010."},{"key":"154553r3","unstructured":"B. Kosi\u0144ska, \u201eDiagnostyka labolatoryjna nieswoistych zapale\u0144 jelit,\u201d Nowiny Lekarskie, tom 75, nr 4, pp. 382-388, 2006."},{"key":"154553r4","unstructured":"M. Molenda, \u201eStres oksydacyjny w nieswoistych zapaleniach jelit,\u201d Rocznik Pomorskiej Akademii Medycznej w Szczecinie, tom 56, nr 2, pp. 28-32, 2010."},{"key":"154553r5","unstructured":"K. Borycka-Kiciak, \u0141. Janaszek i W. Tarnowski, \u201eOperacje ze wskaza\u0144 pilnych w nieswoistych chorobach zapalnych jelit,\u201d Post\u0119py Nauk Medycznych, tom XXVII, nr 8, pp. 569-573, 2014."},{"key":"154553r6","doi-asserted-by":"crossref","unstructured":"J. Evans i i wsp., \u201eHome Total Parenteral Nutrition: An alternative to Early Surgery for Complicated Inlammatory Bowel Disease,\u201d Journal of Gastrointestinal Surgery, tom 7, nr 4, pp. 562-566, 2003.","DOI":"10.1016\/S1091-255X(02)00132-4"},{"key":"154553r7","doi-asserted-by":"crossref","unstructured":"D. Baczewska-Mazurkiewicz i G. Rydzewska, \u201eProblemy \u017cywieniowe pacjent\u00f3w z nieswoistymi chorobami zapalnymi jelit,\u201d Przegl\u0105d Gastroenterologiczny, tom 6, nr 2, pp. 69-77, 2011.","DOI":"10.5114\/pg.2011.21716"},{"key":"154553r8","doi-asserted-by":"crossref","unstructured":"N. Kumar, S. Ahmad, M. Ali, G. Kumar i N. Venu, \u201eInpatient Need for Total Parenteral Nutrition in Inflammatory Bowel Disease Is Associated With Higher Mortality - A Study Using National Inpatient Sample Over the Last Decade 2000-2008,\u201d Gastroenterology, tom 144, nr 5, pp. 748-749, 2013.","DOI":"10.1016\/S0016-5085(13)62774-2"},{"key":"154553r9","doi-asserted-by":"crossref","unstructured":"F. Scaldaferri, M. Pizzoferrato, L. Lopetuso, T. Musca, F. Ingravalle, L. Sicignano i i wsp., \u201eNutrition and IBD: Malnutrition and\/or Sarcopenia?,\u201d Gastroenterology Research and Practice, pp. 1-11, 2017.","DOI":"10.1155\/2017\/8646495"},{"key":"154553r10","unstructured":"C. Hartman, R. Eliakim i R. Shamir, \u201eNutrirional Status and nutritional theraoy in inflammatory bowel diseases,\u201d World J Gastroenterol, tom 15, nr 21, pp. 2570-2578, 2009."},{"key":"154553r11","doi-asserted-by":"crossref","unstructured":"J. Varayil, R. Hurt, F. Enders i D. Kelly, \u201eInfection Rate in Inflammatory Bowel Disease (IBD) Patients on Home Parenteral Nutrition (HPN),\u201d Gastroenterology, tom 144, nr 5, p. 748, 2013.","DOI":"10.1016\/S0016-5085(13)62772-9"},{"key":"154553r12","unstructured":"G. Zaloga, \u201eParenteral nutrition in adult inpatients with functioning gastrointestinal tracts: assessment of outcomes,\u201d Lancet, tom 367, pp. 1101-1111, 2006."},{"key":"154553r13","unstructured":"M. Staun, L. Pironi , F. Bozzetti i i wsp., \u201eWytyczne Espen dotycz\u0105ce \u017cywienia pozajelitowego: \u017cywienie pozajelitowe doros\u0142ych w warunkach domowych (\u017c.p.d.),\u201d Post\u0119py \u017bywienia Klinicznego, tom 8, nr 2, pp. 17-34, 2012."},{"key":"154553r14","doi-asserted-by":"crossref","unstructured":"M. Seo, M. Okada, T. Yao, H. Furukawa i H. Matake, \u201eThe Role of Total Parenteral Nutrition in the Management of Patients With Acute Attacks of Inflammatory Bowel Disease,\u201d Journal of Clinical Gastroenterology, tom 29, nr 3, pp. 270-275, 1999.","DOI":"10.1097\/00004836-199910000-00009"},{"key":"154553r15","doi-asserted-by":"crossref","unstructured":"D. Nguyen, N. Parekh i M. 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Jeejeebhoy, \u201eTotal Parenteral Nutrition and Complete Bowel Rest in the Management of Crohn\u2019s Disease,\u201d JPEN J Parenter Enteral Nutr. , tom 9, nr 3, pp. 280-287, 1985.","DOI":"10.1177\/0148607185009003280"},{"key":"154553r19","unstructured":"Y. Takagi, R. Nezu, A. Kubota, S. Kamata, T. Itakura i A. Okada, \u201eTotal parenteral nutrition in inflammatory bowel disease. An evaluation of its clinical response,\u201d Nihon Geka Gakkai Zasshi, tom 85, nr 9, pp. 1006-1009, 1984."},{"key":"154553r20","doi-asserted-by":"crossref","unstructured":"M. Dibb, M. Soop, A. Teubner, J. Shaffer, A. Abraham, G. Carlson i S. Lal, \u201eSurvival and nutritional dependence on home parenteral nutrition: Three decades of experience from a single referral centre,\u201d Clinical Nutrition, tom 36, nr 2, pp. 570-576, 2017.","DOI":"10.1016\/j.clnu.2016.01.028"},{"key":"154553r21","doi-asserted-by":"crossref","unstructured":"J. Wagner i J. 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