{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:48:00Z","timestamp":1790682480832,"version":"4.1.0"},"reference-count":0,"publisher":"Index Copernicus","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol Pol"],"published-print":{"date-parts":[[2017,12,30]]},"abstract":"<jats:p>Introduction: The diagnostic and therapeutic recommendations have been changing over the years to improve treatment\noutcomes and quality of life of Head and Neck Cancer (HNC) patients.\nAim: The aim of this study was to present currently recommended Head and Neck Cancer treatment guidelines based\non the literature review with particular emphasis on novel approaches the NCCN algorithms.\nMaterial and methods: The review of literature covering articles published in the last five years and pointing out essential\nchanges in HNC treatment regarding evidence based medicine. The study focused on the analysis of novel approaches\nfor the particular primaries, the implementation of biological therapies and personalized cancer therapies.\nResults: Updates in the oncological NCCN guidelines for all ENT primaries except major salivary glands and subglottis\nare based on knowledge derived from the basic sciences, clinical trials and the best evidence available currently.\nThe latest recommendations emphasize value of biological therapies use.\n\n<\/jats:p>","DOI":"10.5604\/01.3001.0010.7193","type":"journal-article","created":{"date-parts":[[2017,12,15]],"date-time":"2017-12-15T16:22:35Z","timestamp":1513354955000},"page":"1-6","source":"Crossref","is-referenced-by-count":29,"title":["Updated National Comprehensive Cancer Network guidelines for treatment of head and neck cancers 2010-2017"],"prefix":"10.5604","volume":"71","author":[{"given":"Ma\u0142gorzata","family":"Wierzbicka","sequence":"first","affiliation":[{"name":"Department of Otolaryngology and Laryngological Oncology, Poznan University of Medical Science, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Napiera\u0142a","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology and Laryngological Oncology, Poznan University of Medical Science, Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3689","container-title":["Otolaryngologia Polska"],"original-title":[],"link":[{"URL":"http:\/\/otolaryngologypl.com\/gicid\/pdf\/01.3001.0010.7193","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T10:33:04Z","timestamp":1515666784000},"score":1,"resource":{"primary":{"URL":"http:\/\/otolaryngologypl.com\/gicid\/01.3001.0010.7193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,30]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,12,30]]}},"URL":"https:\/\/doi.org\/10.5604\/01.3001.0010.7193","relation":{},"ISSN":["0030-6657","2300-8423"],"issn-type":[{"value":"0030-6657","type":"print"},{"value":"2300-8423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,30]]}}}