{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T10:20:37Z","timestamp":1708338037107},"reference-count":0,"publisher":"Index Copernicus","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol Przegl Chir"],"published-print":{"date-parts":[[2018,2,28]]},"abstract":"<jats:p>ntroduction: One of the most important goals of preparing a patient for elective gastrointestinal cancer surgery is prevention\nof postoperative complications. The literature gives many ways to prepare for surgery, but only a few suggests that pre-operative\nuse of rifaximin provides benefits in the form of fewer perioperative complications and reduces the severity of pain during\nthis period.\nO bjective: The presented project is a retrospective analysis of the effectiveness of rifaximin in the prevention of perioperative\ncomplications in patients treated in the Unit of General Surgery with the Orthopedic and Urology in the Hospital of the Ministry\nof the Interior and Administration in Lublin, and a review of international literature in this subject.\nMaterials and methods: A retrospective analysis of the results of pre-operative use of rifaximin was performed in 181 patients\nscheduled for rectal and colorectal cancer between 2013 and 2016 in the General Surgery Unit with the Orthopedic and Urology\nin the Hospital of the Ministry of Interior and Administration in Lublin. Patients undergoing urgent surgery were excluded\nfrom the study.\nPatients were divided into 2 groups. The first group of 139 patients \u2013 patients operated on for rectal and colorectal cancer in\n2013 until 2015, in whom rifaximine was not used in the preoperative period. The second group is 42 patients, operated on in\n2016, in which the rifaximin was used in the pre-operative period at a dose of 2x2 tablets (400 mg) per day, 12-hour interval,\nfor 7 days before the planned operation. Additionally, a probiotic was administered for 7 days. Drugs were ordained at the Oncological\nOutpatient Clinic as part of the pre-hospitalization check.\nR esults: The use of rifaximin in the preoperative period in patients with colorectal cancer had an effect on shortening the time\nof post-operative hospitalization and reduced post-surgical pain in comparison with the control group. The analysis of the cynumber\nand intensity of surgical complications in both groups did not differ.\nC onclusions: Large studies on the influence of rifaximin on the development of colorectal cancer have not been published so\nfar. Only single reports suggest that its use has a positive effect on the perioperative period of patients treated for colorectal\ncancer including rectum and our retrospective analysis confirms these observations.\n\n<\/jats:p>","DOI":"10.5604\/01.3001.0011.5958","type":"journal-article","created":{"date-parts":[[2018,3,2]],"date-time":"2018-03-02T09:54:23Z","timestamp":1519984463000},"page":"35-40","source":"Crossref","is-referenced-by-count":2,"title":["The use of rifaximin in pre-operative period of patients with tumors of\nthe gastrointestinal tract \u2013 a retrospective study (2013-2016)"],"prefix":"10.5604","volume":"90","author":[{"given":"Nina","family":"Moroz","sequence":"first","affiliation":[{"name":"Oddzia\u0142 Chirurgii Og\u00f3lnej z Pododdzia\u0142em Urazowo-Ortopedycznym i Pododdzia\u0142em Urologicznym, Szpital MSWiA w Lublinie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Sitarz","sequence":"additional","affiliation":[{"name":"Oddzia\u0142 Chirurgii Og\u00f3lnej z Pododdzia\u0142em Urazowo-Ortopedycznym i Pododdzia\u0142em Urologicznym, Szpital MSWiA w Lublinie Zak\u0142ad Anatomii Prawid\u0142owej, Uniwersytet Medyczny w Lublinie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Mruk","sequence":"additional","affiliation":[{"name":"Centrum Medyczne Mrukmed, Rzesz\u00f3w, Polska"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Bakalarz","sequence":"additional","affiliation":[{"name":"Klinika Onkologii Klinicznej, Podkarpackie Centrum Onkologii, Rzesz\u00f3w, Polska"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Maci\u0105g","sequence":"additional","affiliation":[{"name":"Oddzia\u0142 Onkologii Klinicznej, Szpital Specjalistyczny im. J. \u015aniadeckiego w Nowym S\u0105czu"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakub","family":"Litwi\u0144ski","sequence":"additional","affiliation":[{"name":"Oddzia\u0142 Chirurgii Og\u00f3lnej z Pododdzia\u0142em Urazowo-Ortopedycznym i Pododdzia\u0142em Urologicznym, Szpital MSWiA w Lublinie"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryszard","family":"Wierzbicki","sequence":"additional","affiliation":[{"name":"6Klinika Chirurgii Onkologicznej, SPSK Nr 1 w Lublinie, Polska"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3689","container-title":["Polish Journal of Surgery"],"original-title":[],"deposited":{"date-parts":[[2018,3,2]],"date-time":"2018-03-02T09:54:29Z","timestamp":1519984469000},"score":1,"resource":{"primary":{"URL":"https:\/\/ppch.pl\/gicid\/01.3001.0011.5958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,28]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2,28]]}},"URL":"https:\/\/doi.org\/10.5604\/01.3001.0011.5958","relation":{},"ISSN":["0032-373X","2299-2847"],"issn-type":[{"value":"0032-373X","type":"print"},{"value":"2299-2847","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,28]]}}}