{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:06:24Z","timestamp":1785542784237,"version":"3.56.0"},"reference-count":0,"publisher":"Index Copernicus","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pol Przegl Chir"],"published-print":{"date-parts":[[2018,8,31]]},"abstract":"<jats:p>Guidelines for the pharmacotherapy of pain in cancer patients were developed by a group of 21 experts of the Polish Association\nfor the Study of Pain, Polish Society of Palliative Medicine, Polish Society of Oncology, Polish Society of Family\nMedicine, Polish Society of Anaesthesiology and Intensive Therapy and Association of Polish Surgeons. During a series of\nmeetings, the experts carried out an overview of the available literature on the treatment of pain in cancer patients, paying\nparticular attention to systematic reviews and more recent randomized studies not included in the reviews. The search was\nperformed in the EMBASE, MEDLINE, and Cochrane Central Register of Controlled Trials databases using such keywords as\n\u201cpain\u201d, \u201ccancer\u201d, \u201cpharmacotherapy\u201d, \u201canalgesics\u201d, and similar. The overviewed articles included studies of pathomechanisms\nof pain in cancer patients, methods for the assessment of pain in cancer patients, and drugs used in the pharmacotherapy\nof pain in cancer patients, including non-opioid analgesics (paracetamol, metamizole, non-steroidal anti-inflammatory\ndrugs), opioids (strong and weak), coanalgesics (glucocorticosteroids, \u03b12-adrenergic receptor agonists, NMDA receptor\nantagonists, antidepressants, anticonvulsants, topical medications) as well as drugs used to reduce the adverse effects of\nthe analgesic treatment and symptoms other than pain in patients subjected to opioid treatment. The principles of opioid\nrotation and the management of patients with opioidophobia were discussed and recommendations for the management\nof opioid-induced hyperalgesia were presented. Drugs used in different types of pain experienced by cancer patients, including\nneuropathic pain, visceral pain, bone pain, and breakthrough pain, were included in the overview. Most common\ninteractions of drugs used in the pharmacotherapy of pain in cancer patients as well as the principles for the management\nof crisis situations. In the final part of the recommendations, the issues of pain and care in dying patients are discussed.\nRecommendations are addressed to physicians of different specialties involved in the diagnostics and treatment of cancer\nin their daily practice. It is the hope of the experts who took part in the development of these recommendations that the recommendations\nwould become helpful in everyday medical practice and thus contribute to the improvement in the quality\nof care and the efficacy of pain treatment in this group of patients.\n\n<\/jats:p>","DOI":"10.5604\/01.3001.0012.2904","type":"journal-article","created":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T07:29:20Z","timestamp":1537169360000},"page":"51-80","source":"Crossref","is-referenced-by-count":6,"title":["Pharmacotherapy of pain in cancer patients \u2013 recommendations of the Polish Association for the Study of Pain, Polish Society of Palliative Medicine, Polish Society of Oncology, Polish Society of Family Medicine, Polish Society of Anaesthesiology and Intensive Therapy and Association of Polish Surgeons"],"prefix":"10.5604","volume":"90","author":[{"given":"Jerzy","family":"Wordliczek","sequence":"first","affiliation":[{"name":"Klinika Intensywnej Terapii Interdyscyplinarnej, Uniwersytet Jagiello\u0144ski, Collegium Medicum, Krak\u00f3w Kliniczny Oddzia\u0142 Anestezjologii i Intensywnej Terapii, Szpital Uniwersytecki, Krak\u00f3w"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Kotli\u0144ska-Lemieszek","sequence":"additional","affiliation":[{"name":"Katedra i Klinika Medycyny Paliatywnej, Uniwersytet Medyczny im. Karola Marcinkowskiego, Pozna\u0144"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Leppert","sequence":"additional","affiliation":[{"name":"Katedra i Klinika Medycyny Paliatywnej, Uniwersytet Medyczny im. Karola Marcinkowskiego, Pozna\u0144"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaros\u0142aw","family":"Woro\u0144","sequence":"additional","affiliation":[{"name":"Zak\u0142ad Farmakologii Klinicznej, Katedra Farmakologii, Uniwersytet Jagiello\u0144ski, Collegium Medicum, Krak\u00f3w"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Dobrogowski","sequence":"additional","affiliation":[{"name":"Zak\u0142ad Badania i Leczenia B\u00f3lu, Katedra Anestezjologii, Uniwersytet Jagiello\u0144ski, Collegium Medicum, Krak\u00f3w"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u0142gorzata","family":"Krajnik","sequence":"additional","affiliation":[{"name":"Katedra i Zak\u0142ad Opieki Paliatywnej, Uniwersytet Miko\u0142aja Kopernika w Toruniu, Collegium Medicum, Bydgoszcz"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Przeklasa-Muszy\u0144ska","sequence":"additional","affiliation":[{"name":"Zak\u0142ad Badania i Leczenia B\u00f3lu, Katedra Anestezjologii, Uniwersytet Jagiello\u0144ski, Collegium Medicum, Krak\u00f3w"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Jassem","sequence":"additional","affiliation":[{"name":"Katedra i Klinika Onkologii i Radioterapii, Gda\u0144ski Uniwersytet Medyczny, Gda\u0144sk"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaros\u0142aw","family":"Drobnik","sequence":"additional","affiliation":[{"name":"Katedra i Zak\u0142ad Medycyny Rodzinnej, Uniwersytet Medyczny, Wroc\u0142aw"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3689","container-title":["Polish Journal of Surgery"],"original-title":[],"deposited":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T07:29:21Z","timestamp":1537169361000},"score":1,"resource":{"primary":{"URL":"https:\/\/ppch.pl\/gicid\/01.3001.0012.2904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,31]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,8,31]]}},"URL":"https:\/\/doi.org\/10.5604\/01.3001.0012.2904","relation":{},"ISSN":["0032-373X","2299-2847"],"issn-type":[{"value":"0032-373X","type":"print"},{"value":"2299-2847","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,31]]}}}