{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T01:54:24Z","timestamp":1779242064987,"version":"3.51.4"},"reference-count":35,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,5,16]],"date-time":"2019-05-16T00:00:00Z","timestamp":1557964800000},"content-version":"vor","delay-in-days":257,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Hepatology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.5604\/01.3001.0012.3138","type":"journal-article","created":{"date-parts":[[2018,8,24]],"date-time":"2018-08-24T11:22:57Z","timestamp":1535109777000},"page":"795-801","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Chronic Hepatitis C Patients with Obesity: Do We Need Two Operators for Accurate Evaluation of Liver Stiffness?"],"prefix":"10.1016","volume":"17","author":[{"given":"Gamal E.","family":"Shiha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahira","family":"El-Etreby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mounir","family":"Bahgat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdy","family":"Hamed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed El","family":"Sherbini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elsayed A.","family":"Ghoneem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled","family":"Zalata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reham E.","family":"Soliman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed A.","family":"ElBasiouny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabiel NH","family":"Mikhail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.5604\/01.3001.0012.3138_bib0005","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1056\/NEJM200102153440706","article-title":"Liver biopsy","volume":"344","author":"Bravo","year":"2001","journal-title":"N Engl J Med"},{"key":"10.5604\/01.3001.0012.3138_bib0010","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1053\/jhep.2001.20534","article-title":"The role of liver biopsy in chronic hepatitis C","volume":"33","author":"Saadeh","year":"2001","journal-title":"Hepatology"},{"key":"10.5604\/01.3001.0012.3138_bib0015","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0168-8278(86)80075-7","article-title":"Complications following percutaneous liver biopsy. A multicentre retrospective study on 68,276 biopsies","volume":"2","author":"Piccinino","year":"1986","journal-title":"J Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0020","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/j.hep.2003.09.022","article-title":"Sampling variability of liver fibrosis in chronic hepatitis C","volume":"38","author":"Bedossa","year":"2003","journal-title":"Hepatology"},{"key":"10.5604\/01.3001.0012.3138_bib0025","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1055\/s-2004-823103","article-title":"Liver biopsy sampling in chronic viral hepatitis","volume":"24","author":"Guido","year":"2004","journal-title":"Semin Liver Dis"},{"key":"10.5604\/01.3001.0012.3138_bib0030","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0168-8278(03)00191-0","article-title":"Impact of liver biopsy size on histological evaluation of chronic viral hepatitis: the smaller the sample, the milder the disease","volume":"39","author":"Colloredo","year":"2003","journal-title":"J Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0035","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/hep.20535","article-title":"Hepatitis Network 49. Sources of variability in histological scoring of chronic viral hepatitis","volume":"41","author":"Rousselet","year":"2005","journal-title":"Hepatology"},{"key":"10.5604\/01.3001.0012.3138_bib0040","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/hep.20506","article-title":"Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C","volume":"41","author":"Ziol","year":"2005","journal-title":"Hepatology"},{"key":"10.5604\/01.3001.0012.3138_bib0045","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1053\/j.gastro.2004.11.018","article-title":"Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C","volume":"128","author":"Castera","year":"2005","journal-title":"Gastroenterology"},{"key":"10.5604\/01.3001.0012.3138_bib0050","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1002\/hep.21420","article-title":"Accuracy of liver stiffness measurement for the diagnosis of cirrhosis in patients with chronic liver diseases","volume":"44","author":"Ganne-Carrie","year":"2006","journal-title":"Hepatology"},{"key":"10.5604\/01.3001.0012.3138_bib0055","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1136\/gut.2006.111302","article-title":"Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease","volume":"56","author":"Fraquelli","year":"2007","journal-title":"Gut"},{"key":"10.5604\/01.3001.0012.3138_bib0060","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1136\/gut.2005.069153","article-title":"Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study","volume":"55","author":"Foucher","year":"2006","journal-title":"Gut"},{"key":"10.5604\/01.3001.0012.3138_bib0065","unstructured":"World Health Organization. Obesity and overweight: Fact Sheet. http:\/\/www.who.int\/mediacentre\/factsheets\/fs311\/ en\/Accessed 4 October 2017."},{"key":"10.5604\/01.3001.0012.3138_bib0070","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/jvh.12296","article-title":"Applicability and accuracy improvement of transient elastography using the M and XL probes by experienced operators","volume":"22","author":"Carri\u00f3n","year":"2015","journal-title":"J Viral Hepat"},{"key":"10.5604\/01.3001.0012.3138_bib0075","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1002\/hep.23425","article-title":"Pitfalls of liver stiffness measurement: a 5-year prospective study of 13,369 examinations","volume":"51","author":"Castera","year":"2010","journal-title":"Hepatology"},{"key":"10.5604\/01.3001.0012.3138_bib0080","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.ultrasmedbio.2015.03.007","article-title":"WFUMB guidelines and recommendations for clinical use of ultrasound elastography: Part 3: liver","volume":"41","author":"Ferraioli","year":"2015","journal-title":"Ultrasound Med Biol"},{"key":"10.5604\/01.3001.0012.3138_bib0085","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1111\/jgh.13762","article-title":"Impact of anthropometric features on the applicability and accuracy of FibroScan\u00ae (M and XL) in overweight\/obese patients","volume":"32","author":"Puigveh\u00ed","year":"2017","journal-title":"J Gastroenterol Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0090","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jhep.2005.08.008","article-title":"Expected increase in hepatitis C related mortality in Egypt due to pre-2000 infections","volume":"44","author":"Deuffic-Burban","year":"2006","journal-title":"J Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0095","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1365-2893.2012.01650.x","article-title":"Towards realistic estimates of HCV incidence in Egypt","volume":"20","author":"Breban","year":"2013","journal-title":"J Viral Hepat"},{"key":"10.5604\/01.3001.0012.3138_bib0100","unstructured":"Ministry of Health and Population, Egypt. Plan of Action for the Prevention, Care and Treatment of Viral Hepatitis, Egypt 2014-2018."},{"key":"10.5604\/01.3001.0012.3138_bib0105","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jhep.2010.06.022","article-title":"Reliability of transient elastography for the detection of fibrosis in nonalcoholic fatty liver disease and chronic viral hepatitis","volume":"54","author":"Gaia","year":"2011","journal-title":"J Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0110","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.jhep.2010.07.033","article-title":"Elastography for the diagnosis of severity of fibrosis in chronic liver disease: a meta-analysis of diagnostic accuracy","volume":"54","author":"Tsochatzis","year":"2011","journal-title":"J Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0115","doi-asserted-by":"crossref","first-page":"e3857","DOI":"10.1371\/journal.pone.0003857","article-title":"Concordance in a world without a gold standard: a new non-invasive methodology for improving accuracy of fibrosis markers","volume":"3","author":"Poynard","year":"2008","journal-title":"PLoS ONE"},{"key":"10.5604\/01.3001.0012.3138_bib0120","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/hep.1840200104","article-title":"Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. The French METAVIR Cooperative Study Group","volume":"20","author":"Bedossa","year":"1994","journal-title":"Hepatology"},{"key":"10.5604\/01.3001.0012.3138_bib0125","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"1","author":"Bland","year":"1986","journal-title":"Lancet"},{"key":"10.5604\/01.3001.0012.3138_bib0130","first-page":"17","article-title":"Comparison between Transient Elastography (FibroScan) and Liver Biopsy for the Diagnosis of Hepatic Fibrosis in Chronic Hepatitis C Patients","volume":"2","author":"Shiha","year":"2016","journal-title":"MJVH"},{"key":"10.5604\/01.3001.0012.3138_bib0135","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.cgh.2008.07.006","article-title":"Reproducibility of liver stiffness measurement by ultrasonographic elastometry","volume":"6","author":"Boursier","year":"2008","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0140","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/MEG.0b013e328331a5d0","article-title":"Interobserver concordance in the assessment of liver fibrosis in HIV\/HCV-coinfected patients using transient elastometry","volume":"22","author":"Neukam","year":"2010","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0145","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1365-2893.2012.01608.x","article-title":"Interobserver discrepancy in liver fibrosis using transient elastography","volume":"19","author":"Roca","year":"2012","journal-title":"J Viral Hepat"},{"key":"10.5604\/01.3001.0012.3138_bib0150","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1111\/liv.12551","article-title":"Interobserver variability in transient elastography analysis of patients with chronic hepatitis C","volume":"35","author":"Perazzo","year":"2015","journal-title":"Liver Int"},{"key":"10.5604\/01.3001.0012.3138_bib0155","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1111\/j.1365-2036.2011.04861.x","article-title":"The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases","volume":"34","author":"Sebastiani","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.5604\/01.3001.0012.3138_bib0160","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.clinre.2011.07.003","article-title":"FibroTest and Fibroscan performances revisited in patients with chronic hepatitis C. Impact of the spectrum effect and the applicability rate","volume":"35","author":"Poynard","year":"2011","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"10.5604\/01.3001.0012.3138_bib0165","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0399-8320(08)73994-0","article-title":"Transient elastography (FibroScan)","volume":"32","author":"De Ledinghen","year":"2008","journal-title":"Gastroenterol Clin Biol"},{"key":"10.5604\/01.3001.0012.3138_bib0170","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1440-1746.2010.06510.x","article-title":"Factors associated with unreliable liver stiffness measurement and its failure with transient elastography in the Chinese population","volume":"26","author":"Wong","year":"2011","journal-title":"J Gastroenterol Hepatol"},{"key":"10.5604\/01.3001.0012.3138_bib0175","doi-asserted-by":"crossref","first-page":"807","DOI":"10.7326\/0003-4819-158-11-201306040-00005","article-title":"Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review","volume":"158","author":"Chou","year":"2013","journal-title":"Ann Intern Med"}],"container-title":["Annals of Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1665268119302571?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1665268119302571?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:37:03Z","timestamp":1761647823000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1665268119302571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S1665268119302571"],"URL":"https:\/\/doi.org\/10.5604\/01.3001.0012.3138","relation":{},"ISSN":["1665-2681"],"issn-type":[{"value":"1665-2681","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic Hepatitis C Patients with Obesity: Do We Need Two Operators for Accurate Evaluation of Liver Stiffness?","name":"articletitle","label":"Article Title"},{"value":"Annals of Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.5604\/01.3001.0012.3138","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2018 Fundaci\u00f3n Cl\u00ednica M\u00e9dica Sur, A.C. Published by Elsevier Espa\u00f1a, S.L.","name":"copyright","label":"Copyright"}]}}