{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T16:05:20Z","timestamp":1648742720133},"reference-count":25,"publisher":"Index Copernicus","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol Pol"],"published-print":{"date-parts":[[2021,12,31]]},"abstract":"<jats:p>In everyday otolaryngological and gastroenterological practice, the diagnosis and treatment of extraesophageal forms of gastroesophageal reflux disease are often challenging. It is sometimes the case that treatment ordered by other specialists proves ineffective or even worsens the symptoms. There is no golden standard of diagnosis for otolaryngological forms of GERD, and currently used tools (gastroscopy, laryngoscopy, impedance and pH testing) have low sensitivity and specificity. After finishing a course of successful treatment, the patients often come back to our offices with the very same symptoms. In order to improve the efficacy of treatment, a prokinetic agent can be added to the standard proton pump inhibitor therapy.\n\n<\/jats:p>","DOI":"10.5604\/01.3001.0015.5165","type":"journal-article","created":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T16:31:17Z","timestamp":1645115477000},"page":"38-44","source":"Crossref","is-referenced-by-count":0,"title":["Itopride in treatment of laryngopharyngeal symptoms of gastroesophageal reflux disease"],"prefix":"10.5604","volume":"75","author":[{"given":"Maria","family":"Janiak","sequence":"first","affiliation":[{"name":"Department and Clinic of Gastroenterology and Hepatology, Medical University of Gdansk, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3689","reference":[{"key":"224233r1","doi-asserted-by":"crossref","unstructured":"Katz P.O., Gerson L.B., Vela M.F.: Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease. Am J Gastroenterol, 2013; 108: 308\u2013328.","DOI":"10.1038\/ajg.2012.444"},{"key":"224233r2","doi-asserted-by":"crossref","unstructured":"Vakil N., van Zanten S.V., Kahrilas R., Dent J., Jones R., Global Consensus Group.: The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol, 2006; 101(8): 1900\u20131920.","DOI":"10.1111\/j.1572-0241.2006.00630.x"},{"key":"224233r3","doi-asserted-by":"crossref","unstructured":"Lechien J.R., Dapri G., Dequanter D. et al.: Surgical treatment for laryngopharyngeal reflux disease: a systematic review. JAMA Otolaryngol Head Neck Surg, 2019; 145(7): 655\u2013666.","DOI":"10.1001\/jamaoto.2019.0315"},{"key":"224233r4","doi-asserted-by":"crossref","unstructured":"Koufman J.A.: the otolaryngologic manifestations of gastroesophageal reflux disease (gerd): a clinical investigation of 225 patients using ambulatory 24-hour ph monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. Laryngoscope, 1991; 101(4): 1.","DOI":"10.1002\/lary.1991.101.s53.1"},{"key":"224233r5","doi-asserted-by":"crossref","unstructured":"Lechien J.R., Saussez S., Harmegnies B. et al.: Laryngopharyngeal reflux and voice disorders: a multifactorial model of etiology and pathophysiology. J Voice, 2017; 31: 733\u2013752.","DOI":"10.1016\/j.jvoice.2017.03.015"},{"key":"224233r6","doi-asserted-by":"crossref","unstructured":"Altman K.W., Kinoshita Y., Tan M., Burstein D., Radosevich J.A.: Western Blot Confirmation of the H+\/K+-ATPase Proton Pump in the Human Larynx and Submandibular Gland. Otolaryngol Head Neck Surg, 2011; 145(5): 783\u2013788.","DOI":"10.1177\/0194599811415589"},{"key":"224233r7","unstructured":"Veerman E.C., Valentijn-Benz M., Nieuw Amerongen A.V.: Viscosity of human salivary mucins: effect of pH and ionic strength and role of sialic acid. J Biol Buccale, 1989; 17: 297\u2013306."},{"key":"224233r8","doi-asserted-by":"crossref","unstructured":"Vaezi M.F.: Are there specific laryngeal signs for GERD? Am J Gastroenterol, 2007. 102: 723\u2013724.","DOI":"10.1111\/j.1572-0241.2007.01143.x"},{"key":"224233r9","doi-asserted-by":"crossref","unstructured":"Vaezi M.F., Pandolfino J.E., Vela M.F., Shaheen N.J.: White Paper AGA: Optimal Strategies to Define and Diagnose Gastroesophageal Reflux Disease. Clin Gastroenterol Hepatol, 2017; 15(8): 1162\u20131172.","DOI":"10.1016\/j.cgh.2017.03.021"},{"key":"224233r10","doi-asserted-by":"crossref","unstructured":"Vaezi M., Hicks D., Abelson T., Richter J.: Laryngeal signs and symptoms and gastroesophageal reflux disease (GERD): a critical assessment of cause and effect association. Clin Gastroenterol Hepatol, 2003; 1: 333\u2013344.","DOI":"10.1053\/S1542-3565(03)00177-0"},{"key":"224233r11","doi-asserted-by":"crossref","unstructured":"Branski R.C., Bhattacharyya N., Shapiro J.: The reliability of the assessment of endoscopic laryngeal findings associated with laryngopharyngeal reflux disease. Laryngoscope, 2002; 112: 1019\u20131024.","DOI":"10.1097\/00005537-200206000-00016"},{"key":"224233r12","doi-asserted-by":"crossref","unstructured":"Ness-Jensen E., Lindam A., Lagergren J., Hveem K.: Weight loss and reduction in gastroesophageal reflux. A prospective population-based cohort study: the HUNT study. Am J Gastroenterol, 2013; 108: 376\u2013382.","DOI":"10.1038\/ajg.2012.466"},{"key":"224233r13","doi-asserted-by":"crossref","unstructured":"Fraser-Moodie C.A., Norton B., Gornall C. et al.: Weight loss has an independent beneficial effect on symptoms of gastro-oesophageal reflux in patients who are overweight. Scand J Gastroenterol, 1999; 34: 337\u2013340.","DOI":"10.1080\/003655299750026326"},{"key":"224233r14","doi-asserted-by":"crossref","unstructured":"Nilsson M., Johnsen R., Ye W. et al.: Lifestyle related risk factors in the aetiology of gastro-oesophageal reflux. Gut, 2004; 53: 1730\u20131735.","DOI":"10.1136\/gut.2004.043265"},{"key":"224233r15","doi-asserted-by":"crossref","unstructured":"Kaltenbach T., Crockett S., Gerson L.B.: Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach. Arch Intern Med, 2006; 166: 965\u2013971.","DOI":"10.1001\/archinte.166.9.965"},{"key":"224233r16","doi-asserted-by":"crossref","unstructured":"Kang J.H., Kang J.Y.: Lifestyle measures in the management of gastro-oesophageal reflux disease: clinical and pathophysiological considerations. Ther Adv Chronic Dis, 2015; 6: 51\u201364.","DOI":"10.1177\/2040622315569501"},{"key":"224233r17","unstructured":"G\u0105siorowska A., Janiak M., Wa\u015bko-Czopnik D. et al.: Post\u0119powanie u pacjent\u00f3w z objawami choroby refluksowej prze\u0142yku \u2013 rekomendacje dla lekarzy rodzinnych. Lekarz POZ, 2019; 5(3): 245\u2013265."},{"key":"224233r18","doi-asserted-by":"crossref","unstructured":"Tack J.: Prokinetics and fundic relaxants in upper functional GI disorders. Curr Opin Pharmacol, 2008; 8: 690\u2212696.","DOI":"10.1016\/j.coph.2008.09.009"},{"key":"224233r19","doi-asserted-by":"crossref","unstructured":"Kim Y.S., Kim T.H., Choi C.S. et al.: Effect of itopride, a new prokinetic, in patients with mild GERD: a pilot study. World J Gastroenterol, 2005; 11: 4210\u20134314.","DOI":"10.3748\/wjg.v11.i27.4210"},{"key":"224233r20","doi-asserted-by":"crossref","unstructured":"Chun B.J., Lee D.S.: The effect of itopride combined with lansoprazole in patients with laryngopharyngeal reflux disease. Eur Arch Otorhinolaryngol, 2013; 270(4): 1385\u20131390.","DOI":"10.1007\/s00405-012-2341-8"},{"key":"224233r21","unstructured":"Ezzat W.F., Fawaz S.A., Fathey H., El Demerdash A.: Virtue of adding prokinetics to proton pump inhibitors in the treatment of laryngopharyngeal reflux disease: prospective study. J Otolaryngol Head Neck Surg, 2011; 40(4): 350\u2013356."},{"key":"224233r22","doi-asserted-by":"crossref","unstructured":"Roman S., Gyawali C.P., Savarino E. et al.: Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: Update of the Porto consensus and recommendations from an international consensus group. Neurogastroenterol Motil, 2017; 29(10): 1\u201315.","DOI":"10.1111\/nmo.13067"},{"key":"224233r23","doi-asserted-by":"crossref","unstructured":"Kessing B.F., Broeders J.A., Vinke N. et al.: Gas-related symptoms after anti-reflux surgery. Surg Endosc, 2013; 27: 3739\u20133747.","DOI":"10.1007\/s00464-013-2959-7"},{"key":"224233r24","unstructured":"G\u0105siorowska A.L.: Refluks krtaniowo-gard\u0142owy \u2013 punkt widzenia gastroenterologa. Gastroenterol Prakt, 2(51)2021; T XIII: 17\u201339."},{"key":"224233r25","doi-asserted-by":"crossref","unstructured":"Barrett C.M., Patel D., Vaezi M.F.: Laryngopharyngeal reflux and atypical gastroesophageal reflux disease. Gastrointest Endoscopy Clin N Am, 2020; 30: 361\u2013376.","DOI":"10.1016\/j.giec.2019.12.004"}],"container-title":["Otolaryngologia Polska"],"original-title":[],"link":[{"URL":"https:\/\/otolaryngologypl.com\/gicid\/pdf\/01.3001.0015.5165","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/otolaryngologypl.com\/gicid\/pdf\/01.3001.0015.5165","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T16:32:10Z","timestamp":1645115530000},"score":1,"resource":{"primary":{"URL":"https:\/\/otolaryngologypl.com\/gicid\/01.3001.0015.5165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,31]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,7,6]]}},"URL":"https:\/\/doi.org\/10.5604\/01.3001.0015.5165","relation":{},"ISSN":["0030-6657","2300-8423"],"issn-type":[{"value":"0030-6657","type":"print"},{"value":"2300-8423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,31]]}}}