{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T05:05:23Z","timestamp":1695359123944},"reference-count":38,"publisher":"Index Copernicus","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngol Pol"],"published-print":{"date-parts":[[2022,12,14]]},"abstract":"<jats:p>&lt;br&gt;&lt;b&gt;Introduction:&lt;\/b&gt; Recently, there has been a significant increase in the number of patients hospitalized and undergoing surgery due to parotid gland tumors. Etiological factors of salivary gland tumors are still unknown. Oxidative stress (OS) has been suggested to be an important indicator of carcinogenesis in some tumors.&lt;\/br&gt; &lt;br&gt;&lt;b&gt;Aim:&lt;\/b&gt; The aim of our study was to assess the state of OS in patients with selected benign and malignant parotid gland tumors.&lt;\/br&gt; &lt;br&gt;&lt;b&gt;Material and method:&lt;\/b? Patients were divided into the following groups i.e. pleomorphic adenoma  35 patients, Warthins tumor (WT)  17, mucoepidermoid carcinoma (MEC)  9, and 45 controls.&lt;\/br&gt; &lt;br&gt;&lt;b&gt;Results:&lt;\/b&gt; We found an increase in plasma lipofuscin levels in patients with all investigated parotid gland tumors. Furthermore, the activity of Cu\/Zn-SOD in Warthins tumor patients was statistically lower compared to the controls, pleomorphic adenoma or mucoepidermoid carcinoma.&lt;\/br&gt; &lt;br&gt;&lt;b&gt;Conclusions:&lt;\/b&gt; In conclusion, we sustain the hypothesis on the presence of low-intensity whole-body OS in patients with parotid gland tumors. Furthermore, LPS may be a useful marker of OS in patients with benign and malignant tumors. Moreover, pathological mechanisms connected with WT seem to be different compared to malignant neoplasms and other benign tumors. It seems that Cu\/Zn-SOD, as an antioxidative enzyme, may play an important role in those mechanisms taking part in WT.&lt;\/br&gt;<\/jats:p>","DOI":"10.5604\/01.3001.0016.1214","type":"journal-article","created":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T07:47:03Z","timestamp":1675151223000},"page":"19-25","source":"Crossref","is-referenced-by-count":1,"title":["Low-intensity whole-body oxidative stress in patients withparotid gland tumors"],"prefix":"10.5604","volume":"77","author":[{"given":"Pawe\u0142","family":"Sowa","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology and Laryngological Oncology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u0142awomir","family":"Kasperczyk","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Dadok","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Laryngological Oncology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Misio\u0142ek","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Laryngological Oncology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Adamczyk-Sowa","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3689","reference":[{"key":"232914r1","doi-asserted-by":"crossref","unstructured":"Speight P.M., Barrett A.W.: Salivary gland tumors. Oral Diseases, 2002;8(5): 229240.","DOI":"10.1034\/j.1601-0825.2002.02870.x"},{"key":"232914r2","unstructured":"El-Naggar A.K., Chan J.K.C., Grandis J.R. et al.: WHO classification odhead and neck tumors, 4th ed. IARC, Lyon 2017."},{"key":"232914r3","doi-asserted-by":"crossref","unstructured":"Licitra L., Grandi C., Prott F.J. et al.: Major and minor salivary glands tumours.Crit Rev Oncol Hematol, 2003; 45: 215225.","DOI":"10.1016\/S1040-8428(02)00005-7"},{"key":"232914r4","doi-asserted-by":"crossref","unstructured":"Mayne S.T., Morse D.E., Winn D.M.: Cancers of the oral cavity and pharynx.In: Cancer Epidemiology and Prevention, ed.: D. Schottenfeld, J.F. Fraumeni.Oxford University Press, New York 2006, 674696.","DOI":"10.1093\/acprof:oso\/9780195149616.003.0035"},{"key":"232914r5","doi-asserted-by":"crossref","unstructured":"Boukheris H., Curtis R.E., Land C.E. et al.: Incidence of carcinoma of themajor salivary glands according to the WHO classification, 1992 to 2006:A population-based study in the United States. Cancer Epidemiol BiomarkersPrev, 2009; 18: 28992906.","DOI":"10.1158\/1055-9965.EPI-09-0638"},{"key":"232914r6","doi-asserted-by":"crossref","unstructured":"Sadetzki S., Chetrit A., Jarus-Hakak A. et al.: Cellular phone use and riskof benign and malignant parotid gland tumors--a nationwide case-controlstudy. Am J Epidemiol., 2008; 167(4): 457467.","DOI":"10.1093\/aje\/kwm325"},{"key":"232914r7","doi-asserted-by":"crossref","unstructured":"Lnn S., Ahlbom A., Christensen H.C. et al.: Mobile phone use and risk ofparotid gland tumor. Am J Epidemiol., 2006; 164(7): 637643.","DOI":"10.1093\/aje\/kwj242"},{"key":"232914r8","unstructured":"Al-Qahtani K.: Mobile Phone Use and the Risk of Parotid Gland Tumors:A Retrospective Case-Control Study. Gulf J Oncolog., 2016; 1(20): 7178."},{"key":"232914r9","doi-asserted-by":"crossref","unstructured":"Land C.E., Saku T., Hayashi Y. et al.: Incidence of salivary gland tumorsamong atomic bomb survivors, 19501987. Evaluation of radiation-relatedrisk. Radiat Res., 1996; 146: 2836.","DOI":"10.2307\/3579392"},{"key":"232914r10","doi-asserted-by":"crossref","unstructured":"White M.C., Holman D.M., Boehm J.E. et al.: Age and cancer risk: a potentiallymodifiable relationship. Am J Prev Med., 2014; 46(3 Suppl 1): S715.doi: 10.1016\/j.amepre.2013.10.029. PMID: 24512933; PMCID: PMC4544764","DOI":"10.1016\/j.amepre.2013.10.029"},{"key":"232914r11","doi-asserted-by":"crossref","unstructured":"Srivastava A., Wang J., Zhou H. et al.: Age and gender related differences inhuman parotid gland gene expression. Arch Oral Biol., 2008; 53(11): 1058 70 doi: 10.1016\/j.archoralbio.2008.05.006. Epub 2008 Jun 20.","DOI":"10.1016\/j.archoralbio.2008.05.006"},{"key":"232914r12","doi-asserted-by":"crossref","unstructured":"Egea J., Fabregat I., Frapart Y.M. et al.: European contribution to the studyof ROS: A summary of the findings and prospects for the future fromthe COST action BM1203 (EU-ROS). Redox Biol., 2017; 13: 94162. doi:10.1016\/j.redox.2017.05.007.","DOI":"10.1016\/j.redox.2017.05.007"},{"key":"232914r13","doi-asserted-by":"crossref","unstructured":"Brunk U.T., Terman A.: Lipofuscin: mechanism of age-related accumulationand influence on cell functions. Free Rad. Biol. Med., 2002; 33(5): 611619.","DOI":"10.1016\/S0891-5849(02)00959-0"},{"key":"232914r14","doi-asserted-by":"crossref","unstructured":"Kandlur A., Satyamoorthy K., Gangadharan G.: Oxidative Stress in Cognitiveand Epigenetic Aging: A Retrospective Glance. Front Mol Neurosci.,2020; 13: 41.","DOI":"10.3389\/fnmol.2020.00041"},{"key":"232914r15","doi-asserted-by":"crossref","unstructured":"Kudryavtseva A.V., Krasnov G.S., Dmitriev A.A. et al.: Mitochondrial dysfunctionand oxidative stress in aging and cancer. Oncotarget., 2016; 7(29):4487944905. doi: 10.18632\/oncotarget.9821.","DOI":"10.18632\/oncotarget.9821"},{"key":"232914r16","unstructured":"Adamczyk-Sowa M., Pierzchala K., Sowa P.: Influence of melatonin supplementationon serum antioxidative properties and impact of the quality oflife in multiple sclerosis patients. J Physiol Pharmacol, 2014; 65(4): 543550."},{"key":"232914r17","doi-asserted-by":"crossref","unstructured":"Li J., Lei J., He L. et al.: Evaluation and Monitoring of Superoxide Dismutase(SOD) Activity and its Clinical Significance in Gastric Cancer:A Systematic Review and Meta-Analysis. Med Sci Monit., 2019; 25: 2032 2042 doi: 10.12659\/MSM.913375. PMID: 30886134; PMCID: PMC6436205.","DOI":"10.12659\/MSM.913375"},{"key":"232914r18","doi-asserted-by":"crossref","unstructured":"Knekt P., Aromaa A., Maatela J. et al.: Serum ceruloplasmin and the riskof cancer in Finland. Br J Cancer., 1992; 65(2): 292296. doi: 10.1038\/bjc.1992.58. PMID: 1739632; PMCID: PMC1977734.","DOI":"10.1038\/bjc.1992.58"},{"key":"232914r19","doi-asserted-by":"crossref","unstructured":"Shah P.H., Venkatesh R., More C.B.: Determination of role of ceruloplasminin oral potentially malignant disorders and oral malignancy-A cross--sectional study. Oral Dis., 2017; 23(8): 10661071. doi: 10.1111\/odi.12690.","DOI":"10.1111\/odi.12690"},{"key":"232914r20","doi-asserted-by":"crossref","unstructured":"Chapman A.L., Mocatta T.J., Shiva S. et al.: Ceruloplasmin is an endogenousinhibitor of myeloperoxidase. J Biol Chem., 2013; 288(9):64656477. doi: 10.1074\/jbc.M112.418970. Epub 2013 Jan 10. PMID:23306200; PMCID: PMC3585080.","DOI":"10.1074\/jbc.M112.418970"},{"key":"232914r21","doi-asserted-by":"crossref","unstructured":"Sodergren E., Nourooz-Zadeh J., Berglund L., Vessby B.: Re-evaluation ofthe ferrous oxidation in xylenol orange assay for the measurement of plasmalipid hydroperoxides. Journal of Biochemical and Biophysical Methods.,1998; 37(3): 137146. doi: 10.1016\/S0165-022X(98)00025-6.","DOI":"10.1016\/S0165-022X(98)00025-6"},{"key":"232914r22","doi-asserted-by":"crossref","unstructured":"Ohkawa H., Ohishi N., Yagi K.: Assay for lipid peroxides in animal tissues bythiobarbituric acid reaction. Analytical Biochemistry., 1979; 95(2): 351358,","DOI":"10.1016\/0003-2697(79)90738-3"},{"key":"232914r23","doi-asserted-by":"crossref","unstructured":"Tsuchida M., Miura T., Mizutani K., Aibara K.: Fluorescent substances inmouse and human sera as a parameter of in vivo lipid peroxidation. Biochimicaet Biophysica Acta (BBA) - Lipids and Lipid Metabolism., 1985;834(2): 196204. doi: 10.1016\/0005-2760(85)90156-0.","DOI":"10.1016\/0005-2760(85)90156-0"},{"key":"232914r24","doi-asserted-by":"crossref","unstructured":"Erel O.: A new automated colorimetric method for measuring total oxidantstatus. Clinical Biochemistry., 2005; 38(12): 11031111. doi: 10.1016\/j.clinbiochem.2005.08.008.","DOI":"10.1016\/j.clinbiochem.2005.08.008"},{"key":"232914r25","doi-asserted-by":"crossref","unstructured":"Oyanagui Y.: Reevaluation of assay methods and establishment of kit forsuperoxide dismutase activity. Analytical Biochemistry., 1984; 142(2): 290 296 doi: 10.1016\/0003-2697(84)90467-6.","DOI":"10.1016\/0003-2697(84)90467-6"},{"key":"232914r26","doi-asserted-by":"crossref","unstructured":"Prasad S., Gupta S.C., Pandey M.K. et al.: Oxidative Stress and Cancer: Advancesand Challenges. Oxid Med Cell Longev., 2016; 2016: 5010423. doi:10.1155\/2016\/5010423. Epub 2016 May 16.","DOI":"10.1155\/2016\/5010423"},{"key":"232914r27","doi-asserted-by":"crossref","unstructured":"Sowa P., Misiolek M., Pasinski B. et al.: Oxidative Stress Markers Patientswith Parotid Gland Tumors: A Pilot Study. Biomed Res Int., 2018; 2018: 4340871 doi: 10.1155\/2018\/4340871. eCollection 2018.","DOI":"10.1155\/2018\/4340871"},{"key":"232914r28","unstructured":"Chulam T.C., Noronha Francisco A.L., Goncalves Filho J. et al.: Warthinstumour of the parotid gland: our experience. Acta Otorhinolaryngol Ital.,2013; 33(6): 393397. PMID: 24376295; PMCID: PMC3870448."},{"key":"232914r29","doi-asserted-by":"crossref","unstructured":"Sowa P., Misiolek M., Orecka B. et al.: Serum levels of selected adipocytokinesin benign and malignant parotid gland tumor patients. Cytokine.,2018; 106: 4044. doi: 10.1016\/j.cyto.2018.03.004.","DOI":"10.1016\/j.cyto.2018.03.004"},{"key":"232914r30","doi-asserted-by":"crossref","unstructured":"Mahmoodi M., Zhang S., Salim S. et al.: Lipofuscin pigment can be usedas a prognostic marker in prostatic adenocarcinoma. Ann Diagn Pathol.,2006; 10(5): 257262.","DOI":"10.1016\/j.anndiagpath.2005.12.007"},{"key":"232914r31","doi-asserted-by":"crossref","unstructured":"Buchner A., David R.: Lipofuscin in salivary glands in health and disease.Oral Surg Oral Med Oral Pathol., 1978; 46(1): 7986.","DOI":"10.1016\/0030-4220(78)90441-3"},{"key":"232914r32","doi-asserted-by":"crossref","unstructured":"Sowa P., Misiolek M., Zielinski M. et al.: Novel interleukin-33 and its solubleST2 receptor as potential serum biomarkers in parotid gland tumors. Exp BiolMed (Maywood), 2018; 243(9): 762769. doi: 10.1177\/1535370218774539.","DOI":"10.1177\/1535370218774539"},{"key":"232914r33","doi-asserted-by":"crossref","unstructured":"Biswas S.K.: Does the interdependence between oxidative stress and inflammationexplain the antioxidant paradox? Oxid. Med. Cell Longev.,2016; 2016: 5698931.","DOI":"10.1155\/2016\/5698931"},{"key":"232914r34","doi-asserted-by":"crossref","unstructured":"Holley A.K., Miao L., St Clair D.K. et al.: Redox-modulated phenomenaand radiation therapy: the central role of superoxide dismutases. Antioxid.Redox Signal., 2014; 20(10): 15671589.","DOI":"10.1089\/ars.2012.5000"},{"key":"232914r35","doi-asserted-by":"crossref","unstructured":"Konzack A., Jakupovic M., Kubaichuk K. et al.: Mitochondrial dysfunctiondue to lack of manganese superoxide dismutase promotes hepatocarcinogenesis.Antioxid. Redox Signal., 2015; 23(14): 10591075.","DOI":"10.1089\/ars.2015.6318"},{"key":"232914r36","doi-asserted-by":"crossref","unstructured":"Weydert C.J., Waugh T.A., Ritchie J.M. et al.: Oberley LW. Overexpressionof manganese or copper-zinc superoxide dismutase inhibits breast cancergrowth. Free Radic Biol Med., 2006; 41(2): 226237. Epub 2006 May 4.","DOI":"10.1016\/j.freeradbiomed.2006.03.015"},{"key":"232914r37","doi-asserted-by":"crossref","unstructured":"Kasapovi, J., Peji, S., Todorovi, A. et al.: Antioxidant status and lipidperoxidation in the blood of breast cancer patients of different ages. CellBiochem. Funct., 2008; 26: 723730. doi:10.1002\/cbf.1499","DOI":"10.1002\/cbf.1499"},{"key":"232914r38","doi-asserted-by":"crossref","unstructured":"Svensk A.M., Soini Y., Pkk P. et al.: Differential expression of superoxidedismutases in lung cancer. Am J Clin Pathol., 2004; 122(3): 395404.","DOI":"10.1309\/A45QHB0QRRX6CT9A"}],"container-title":["Otolaryngologia Polska"],"original-title":[],"link":[{"URL":"https:\/\/otolaryngologypl.com\/gicid\/pdf\/01.3001.0016.1214","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/otolaryngologypl.com\/gicid\/pdf\/01.3001.0016.1214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T06:11:25Z","timestamp":1686723085000},"score":1,"resource":{"primary":{"URL":"https:\/\/otolaryngologypl.com\/gicid\/01.3001.0016.1214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,14]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,9,27]]}},"URL":"https:\/\/doi.org\/10.5604\/01.3001.0016.1214","relation":{},"ISSN":["0030-6657","2300-8423"],"issn-type":[{"value":"0030-6657","type":"print"},{"value":"2300-8423","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,14]]}}}