{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:42:36Z","timestamp":1792226556039,"version":"4.4.0"},"reference-count":22,"publisher":"Baycinar Tibbi Yayincilik","issue":"4","license":[{"start":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:00:00Z","timestamp":1790467200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Agri"],"accepted":{"date-parts":[[2026,8,26]]},"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    This study aims to compare the clinical and procedural outcomes of transforaminal epidural steroid injections (TFESIs) and parasagittal interlaminar epidural steroid injections (P-ILESIs) in patients with unilateral radicular pain secondary to lumbar disc herniation (LDH).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Patients and Methods:<\/jats:bold>\n                    Between January 2024 and June 2025, a total of 162 patients with unilateral radicular pain caused by single-level LDH were included in this retrospective, observational cohort study. The patients were divided into the two groups based on the technique as the TFESI group (n = 82) and the P-ILESI group (n = 80). Pain, disability, sleep quality, and health-related quality of life were assessed using the Numeric Rating Scale (NRS), Oswestry Disability Index (ODI), Pittsburgh Sleep Quality Index (PSQI), and Short Form-12 (SF-12), respectively at baseline, one month, and six months. Fluoroscopy time and cumulative radiation dose were also recorded.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Of the patients, 120 were male and 42 were female with a median age of 47 (range 22 to 65) years. Both techniques significantly improved pain, disability, sleep quality, and quality of life at one and six months (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001). The reduction in NRS from baseline was greater with TFESI at one month (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.008), but not at six months (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.545). The ODI scores were lower with TFESI at one month, although the magnitude of improvement from baseline did not significantly differ and no difference was observed at six months. Quality of life outcomes were comparable between the groups. The P-ILESI required longer fluoroscopy time and higher radiation exposure than TFESI (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001 for both). No major complications occurred, and minor adverse events were infrequent and comparable between the groups (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.764).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Both TFESI and P-ILESI appear to be effective and safe approaches for the treatment of radicular pain associated with LDH. The choice of epidural approach should be individualized according to clinical and anatomical considerations, as well as operator experience.\n                  <\/jats:p>","DOI":"10.5606\/agri.2026.96","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:31:27Z","timestamp":1792225887000},"page":"237-246","source":"Crossref","is-referenced-by-count":0,"title":["A comparison of clinical and procedural outcomes of transforaminal versus parasagittal interlaminar epidural steroid injections for radicular pain secondary to lumbar disc herniation"],"prefix":"10.5606","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3792-8323","authenticated-orcid":false,"given":"Salim Taner","family":"G\u00f6z\u00fck\u0131z\u0131l","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3029-1748","authenticated-orcid":false,"given":"Halil \u0130brahim","family":"Altun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3570","published-online":{"date-parts":[[2026,9,27]]},"reference":[{"key":"ref-1","doi-asserted-by":"crossref","unstructured":"Hoy D, March L, Brooks P, Blyth F, Woolf A, Bain C, et al. The global burden of low back pain: Estimates from the Global Burden of Disease 2010 study. Ann Rheum Dis 2014;73:968-74. doi: 10.1136\/ annrheumdis-2013-204428.","DOI":"10.1136\/annrheumdis-2013-204428"},{"key":"ref-2","doi-asserted-by":"crossref","unstructured":"Martin BI, Deyo RA, Mirza SK, Turner JA, Comstock BA, Hollingworth W, et al. Expenditures and health status among adults with back and neck problems. JAMA 2008;299:656-64. doi: 10.1001\/ jama.299.6.656.","DOI":"10.1001\/jama.299.6.656"},{"key":"ref-3","doi-asserted-by":"crossref","unstructured":"Carlson H, Carlson N. An overview of the management of persistent musculoskeletal pain. Ther Adv Musculoskelet Dis 2011;3:91-9. doi: 10.1177\/1759720X11398742.","DOI":"10.1177\/1759720X11398742"},{"key":"ref-4","doi-asserted-by":"crossref","unstructured":"Boswell MV, Hansen HC, Trescot AM, Hirsch JA. Epidural steroids in the management of chronic spinal pain and radiculopathy. Pain Physician 2003;6:319-34.","DOI":"10.36076\/ppj.2003\/6\/319"},{"key":"ref-5","doi-asserted-by":"crossref","unstructured":"Manchikanti L, Abdi S, Atluri S, Benyamin RM, Boswell MV, Buenaventura RM, et al. An update of comprehensive evidencebased guidelines for interventional techniques in chronic spinal pain. Part II: Guidance and recommendations. Pain Physician 2013;16:S49-283.","DOI":"10.36076\/ppj.2013\/16\/S49"},{"key":"ref-6","unstructured":"Schaufele MK, Hatch L, Jones W. Interlaminar versus transforaminal epidural injections for the treatment of symptomatic lumbar intervertebral disc herniations. Pain Physician 2006;9:361-6."},{"key":"ref-7","doi-asserted-by":"crossref","unstructured":"Ghai B, Vadaje KS, Wig J, Dhillon MS. Lateral parasagittal versus midline interlaminar lumbar epidural steroid injection for management of low back pain with lumbosacral radicular pain: A double-blind, randomized study. Anesth Analg 2013;117:219-27. doi: 10.1213\/ANE.0b013e3182910a15.","DOI":"10.1213\/ANE.0b013e3182910a15"},{"key":"ref-8","doi-asserted-by":"crossref","unstructured":"Bensler S, Walde M, Fischer MA, Pfirrmann CW, Peterson CK, Sutter R. Comparison of treatment outcomes in lumbar disc herniation patients treated with epidural steroid injections: Interlaminar versus transforaminal approach. Acta Radiol 2020;61:361-9. doi: 10.1177\/0284185119858681.","DOI":"10.1177\/0284185119858681"},{"key":"ref-9","doi-asserted-by":"crossref","unstructured":"Mandell JC, Czuczman GJ, Gaviola GC, Ghazikhanian V, Cho CH. The lumbar neural foramen and transforaminal epidural steroid injections: An anatomic review with key safety considerations in planning the percutaneous approach. AJR Am J Roentgenol 2017;209:W26-35. doi: 10.2214\/AJR.16.17471.","DOI":"10.2214\/AJR.16.17471"},{"key":"ref-10","doi-asserted-by":"crossref","unstructured":"Chang-Chien GC, Knezevic NN, McCormick Z, Chu SK, Trescot AM, Candido KD. Transforaminal versus interlaminar approaches to epidural steroid injections: A systematic review of comparative studies for lumbosacral radicular pain. Pain Physician 2014;17:E509-24.","DOI":"10.36076\/ppj.2014\/17\/E509"},{"key":"ref-11","doi-asserted-by":"crossref","unstructured":"Gen\u00e7 Perdecio\u011flu GR, Y\u0131ld\u0131z G, Akkaya \u00d6T, Can E, Y\u00fcr\u00fck D. Parasagittal interlaminar and transforaminal epidural steroid injections for radicular low back pain; Which is more comfortable? Turk J Anaesthesiol Reanim 2023;51:504-9. doi: 10.4274\/ TJAR.2023.231470.","DOI":"10.4274\/TJAR.2023.231470"},{"key":"ref-12","doi-asserted-by":"crossref","unstructured":"Eworuke E, Crisafi L, Liao J, Akhtar S, Van Clief M, Racoosin JA, et al. Risk of serious spinal adverse events associated with epidural corticosteroid injections in the Medicare population. Reg Anesth Pain Med 2021;46:203-9. doi: 10.1136\/rapm-2020-101778.","DOI":"10.1136\/rapm-2020-101778"},{"key":"ref-13","doi-asserted-by":"crossref","unstructured":"Fardon DF, Williams AL, Dohring EJ, Murtagh FR, Gabriel Rothman SL, Sze GK. Lumbar disc nomenclature: Version 2.0: Recommendations of the combined task forces of the North American Spine Society, the American Society of Spine Radiology and the American Society of Neuroradiology. Spine J 2014;14:2525-45. doi: 10.1016\/j.spinee.2014.04.022.","DOI":"10.1016\/j.spinee.2014.04.022"},{"key":"ref-14","doi-asserted-by":"crossref","unstructured":"Wei G, Liang J, Chen B, Zhou C, Ru N, Chen J, et al. Comparison of transforaminal verse interlaminar epidural steroid injection in low back pain with lumbosacral radicular pain: A meta-analysis of the literature. Int Orthop 2016;40:2533-45. doi: 10.1007\/s00264-016- 3220-5.","DOI":"10.1007\/s00264-016-3220-5"},{"key":"ref-15","doi-asserted-by":"crossref","unstructured":"Lee JH, Shin KH, Park SJ, Lee GJ, Lee CH, Kim DH, et al. Comparison of clinical efficacy between transforaminal and interlaminar epidural injections in lumbosacral disc herniation: A systematic review and meta-analysis. Pain Physician 2018;21:433-48.","DOI":"10.36076\/ppj.2018.5.433"},{"key":"ref-16","doi-asserted-by":"crossref","unstructured":"Rados I, Sakic K, Fingler M, Kapural L. Efficacy of interlaminar vs transforaminal epidural steroid injection for the treatment of chronic unilateral radicular pain: Prospective, randomized study. Pain Med 2011;12:1316-21. doi: 10.1111\/j.1526-4637.2011.01213.x.","DOI":"10.1111\/j.1526-4637.2011.01213.x"},{"key":"ref-17","doi-asserted-by":"crossref","unstructured":"Makkar JK, Gourav KKP, Jain K, Singh PM, Dhatt SS, Sachdeva N, et al. Transforaminal versus lateral parasagittal versus midline interlaminar lumbar epidural steroid injection for management of unilateral radicular lumbar pain: A randomized double-blind trial. Pain Physician 2019;22:561-73.","DOI":"10.36076\/ppj\/2019.22.561"},{"key":"ref-18","doi-asserted-by":"crossref","unstructured":"Khojasteh N, Majedi H, Meibodi AE, Khajehnasiri A, Yekta RA, Yazdi NAN, et al. Comparison of epidural space contrast flow and clinical outcomes in parasagittal versus transforaminal epidural steroid injection. Sci Rep 2026;16:7127. doi: 10.1038\/s41598-026-36056-6.","DOI":"10.1038\/s41598-026-36056-6"},{"key":"ref-19","doi-asserted-by":"crossref","unstructured":"Hong JH, Park EK, Park KB, Park JH, Jung SW. Comparison of clinical efficacy in epidural steroid injections through transforaminal or parasagittal approaches. Korean J Pain 2017;30:220-8. doi: 10.3344\/ kjp.2017.30.3.220.","DOI":"10.3344\/kjp.2017.30.3.220"},{"key":"ref-20","doi-asserted-by":"crossref","unstructured":"Miller DL, Balter S, Cole PE, Lu HT, Schueler BA, Geisinger M, et al. Radiation doses in interventional radiology procedures: The RAD-IR study: Part I: Overall measures of dose. J Vasc Interv Radiol 2003;14:711-27. doi: 10.1097\/01.rvi.0000079980.80153.4b.","DOI":"10.1097\/01.RVI.0000079980.80153.4B"},{"key":"ref-21","doi-asserted-by":"crossref","unstructured":"Lee E, Lee JW, Kang HS. Interlaminar versus transforaminal epidural steroid injections: A review of efficacy and safety. Skeletal Radiol 2023;52:1825-40. doi: 10.1007\/s00256-022-04124-3.","DOI":"10.1007\/s00256-022-04124-3"},{"key":"ref-22","doi-asserted-by":"crossref","unstructured":"El-Yahchouchi CA, Plastaras CT, Maus TP, Carr CM, McCormick ZL, Geske JR, et al. Adverse event rates associated with transforaminal and interlaminar epidural steroid injections: A multi-institutional study. Pain Med 2016;17:239-49. doi: 10.1111\/pme.12896.","DOI":"10.1111\/pme.12896"}],"container-title":["A\u011fr\u0131 - The Journal of The Turkish Society of Algology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/agridergisi.com\/tam-metin-pdf\/996\/eng","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/agridergisi.com\/tam-metin-pdf\/996\/eng","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:31:42Z","timestamp":1792225902000},"score":1,"resource":{"primary":{"URL":"https:\/\/agridergisi.com\/doi\/10.5606\/agri.2026.96"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,27]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,10,1]]}},"URL":"https:\/\/doi.org\/10.5606\/agri.2026.96","relation":{},"ISSN":["1300-0012","2458-9446"],"issn-type":[{"value":"1300-0012","type":"print"},{"value":"2458-9446","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,27]]}}}