{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:29:12Z","timestamp":1777465752186,"version":"3.51.4"},"reference-count":0,"publisher":"AVES YAYINCILIK A.\u015e.","issue":"3","license":[{"start":{"date-parts":[[2017,9,30]],"date-time":"2017-09-30T00:00:00Z","timestamp":1506729600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Archives of Rheumatology"],"abstract":"<jats:p>Objectives: This study aims to investigate the relationships between serum endocan, vascular endothelial growth factor (VEGF), and tumor necrosis factor-alpha (TNF-\u03b1) levels in active Beh\u00e7et disease.\r\nPatients and methods: Forty patients with active Beh\u00e7et disease (24 males, 16 females; mean age 37.6\u00b18.7 years; range 20 to 50 years) and 40 healthy controls (22 males, 18 females; mean age 38.8\u00b17.9 years; range 21 to 52 years) were included in this study. Both patient and control groups underwent a complete systemic and ophthalmic examination by the same specialist. Endocan, VEGF, and TNF-\u03b1 levels were measured with an enzyme-linked immunosorbent assay kit in all subjects.\r\nResults: Serum endocan levels were 775.2\u00b1479.3 ng\/mL and 275.8\u00b1145.8 ng\/mL in the patient and control groups, respectively. VEGF levels were 1768.2\u00b1900.5 pg\/mL and 980.2\u00b1135.3 pg\/mL in the patient and control groups, respectively. TNF-\u03b1 levels were 22.4\u00b174.3 pg\/mL-1 and 11.4\u00b116.9 pg\/mL-1 in the patient and control groups, respectively. There was a statistically significant difference between groups in terms of serum endocan, VEGF, and TNF-\u03b1 levels. There was a significant positive correlation between serum endocan and VEGF levels in the patient group (r=0.630; p<\/jats:p>","DOI":"10.5606\/archrheumatol.2017.6072","type":"journal-article","created":{"date-parts":[[2018,1,14]],"date-time":"2018-01-14T16:15:33Z","timestamp":1515946533000},"page":"197-202","source":"Crossref","is-referenced-by-count":16,"title":["Endocan Measurement for Active Beh\u00e7et Disease"],"prefix":"10.5152","volume":"32","author":[{"family":"Ayhan KUL","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Orhan ATE\u015e","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Meltem ALKAN MEL\u0130KO\u011eLU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Mahir U\u011eUR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Nurinnisa \u00d6ZT\u00dcRK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"G\u00fcls\u00fcm ERKAYHAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"\u0130brahim KO\u00c7ER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3111","published-online":{"date-parts":[[2017,9,30]]},"container-title":["Archives of Rheumatology"],"original-title":[],"link":[{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/871\/1436","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/871\/1437","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/download\/871\/1436","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T10:38:48Z","timestamp":1761215928000},"score":1,"resource":{"primary":{"URL":"https:\/\/archivesofrheumatology.org\/index.php\/pub\/article\/view\/871"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,30]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,9,30]]}},"URL":"https:\/\/doi.org\/10.5606\/archrheumatol.2017.6072","relation":{},"ISSN":["2618-6500"],"issn-type":[{"value":"2618-6500","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,30]]}}}