{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T14:50:53Z","timestamp":1782226253980,"version":"3.54.5"},"reference-count":36,"publisher":"Galenos Yayinevi","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turk Gogus Kalp Dama"],"accepted":{"date-parts":[[2025,3,11]]},"published-print":{"date-parts":[[2025,4,1]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic>Background:<\/jats:italic>\n                    <\/jats:bold>\n                    In this study, we aimed to investigate the prognostic value of the tricuspid annular systolic excursion\/pulmonary arterial systolic pressure (TAPSE\/PASP) ratio as a marker of right ventricle-pulmonary artery uncoupling in patients listed for lung transplantation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Methods:<\/jats:italic>\n                    <\/jats:bold>\n                    Between January 2011 and December 2020, a total of 173 patients (114 males, 59 females; mean age: 53.1\u00b112.5 years; range, 18 to 77 years) who had advanced lung disease or pulmonary vascular disease and were included in the lung transplant list were retrospectively analyzed. Demographic characteristics, laboratory values, long-term mortality data, and clinical and cardiac catheterization data of the patients were compared using a TAPSE\/PASP cut-off value of 0.55 mm\/mmHg. The univariate and multivariate regression analyses were performed to identify the value of TAPSE\/PASP ratio in predicting long-term mortality. The maximal selective rank test was carried out to determine the optimal cut-off value for TAPSE\/PASP ratio.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Results:<\/jats:italic>\n                    <\/jats:bold>\n                    The univariate regression analysis revealed that the TAPSE\/PASP ratio, six-minute walk distance, and albumin level were found to be predictors of mortality (hazard ratio [HR]=0.61, 95% confidence interval [CI]: 0.46-0.80, p=0.007; HR=0.72, 95% CI: 0.56-0.91, p=0.007; and HR=0.77, 95% CI: 0.59-0.99, p=0.04, respectively). In the multivariate regression analysis, the TAPSE\/PASP ratio, body mass index, and six-minute walk distance were the predictors of mortality (HR=0.49, 95% CI: 0.34-0.70, p=0.004; HR=0.71, 95% CI: 0.51-0.97, p=0.03; and HR=0.71, 95% CI: 0.54-0.94, p=0.01, respectively).Through the maximal selective rank test, the optimal threshold value for TAPSE\/PASP ratio was found to be 0.29 mm\/mmHg. Patients with TAPSE\/PASP &gt;0.29 mm\/ mmHg had an average life expectancy of 47.8 months, while the patients with TAPSE\/PASP &lt;0.29 mm\/mmHg had an average life expectancy of 17.2 months.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Conclusion:<\/jats:italic>\n                    <\/jats:bold>\n                    Our study results suggest that a TAPSE\/PASP ratio of &lt;0.29 mm\/mmHg is a poor prognostic factor for long-term mortality in patients on the waiting list for lung transplantation.\n                  <\/jats:p>","DOI":"10.5606\/tgkdc.dergisi.2025.26847","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T08:38:52Z","timestamp":1749544732000},"page":"165-175","source":"Crossref","is-referenced-by-count":2,"title":["The prognostic value of the TAPSE\/PASP ratio in lung transplant candidates"],"prefix":"10.4274","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0841-1301","authenticated-orcid":false,"given":"Kadir","family":"B\u0131y\u0131kl\u0131","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5879-2245","authenticated-orcid":false,"given":"Berhan","family":"Keskin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0438-2021","authenticated-orcid":false,"given":"Ali","family":"Karag\u00f6z","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1277-513X","authenticated-orcid":false,"given":"P\u0131nar","family":"Atag\u00fcn G\u00fcney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9463-7878","authenticated-orcid":false,"given":"Erdal","family":"Ta\u015f\u00e7\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3204-7498","authenticated-orcid":false,"given":"Mustafa","family":"Vayvada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9714-2966","authenticated-orcid":false,"given":"Ne\u015fri","family":"Dan\u0131\u015fman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1443-4307","authenticated-orcid":false,"given":"G\u00f6khan","family":"Al\u0131c\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2811","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"ref-1","doi-asserted-by":"crossref","unstructured":"Cooper JD, Patterson GA, Trulock EP. 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