{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T14:49:52Z","timestamp":1782226192545,"version":"3.54.5"},"reference-count":18,"publisher":"Galenos Yayinevi","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Turk Gogus Kalp Dama"],"accepted":{"date-parts":[[2025,9,26]]},"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    This study aims to compare the mid-term clinical and echocardiographic outcomes of quadrangular resection (QR) and butterfly resection (BR) techniques in patients with isolated posterior leaflet prolapse and\/or chordal rupture due to Barlow\u2019s disease.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Between May 2009 and January 2023, a total of 142 patients (89 males, 53 females; mean age: 56.6\u00b111.9 years; range, 20 to 84 years) who underwent mitral valve repair with either QR (n=69) or BR (n=73) were retrospectively analyzed. Patients were evaluated using transthoracic and transesophageal echocardiography preoperatively, intraoperatively, and during mid-term follow-up. Clinical variables, echocardiographic parameters, and surgical data were compared between groups.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Baseline characteristics and preoperative echocardiographic findings were similar between the two groups. Both techniques resulted in significant improvements in the New York Heart Association functional class, mitral regurgitation severity, and left ventricular dimensions. However, the BR group demonstrated significantly improved posterior leaflet mobility (Wilkins score 1.97\u00b10.74\n                    <jats:italic>vs.<\/jats:italic>\n                    3.23\u00b10.79; p&lt;0.001) and lower mean mitral valve gradient (3 [range, 2 to 4]\n                    <jats:italic>vs.<\/jats:italic>\n                    6 [range, 5 to 7] mmHg; p&lt;0.001). Coaptation depth was also significantly reduced in the BR group, indicating a more annular-level coaptation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Butterfly resection is a technically feasible, effective, and anatomically favorable technique for mitral valve repair in Barlow\u2019s disease. Its ability to preserve leaflet mobility and minimize mitral gradients makes it a valuable addition to the surgical armamentarium, particularly in anatomically complex cases.\n                  <\/jats:p>","DOI":"10.5606\/tgkdc.dergisi.2025.28462","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T10:39:55Z","timestamp":1762857595000},"page":"401-411","source":"Crossref","is-referenced-by-count":0,"title":["Midterm outcomes of quadrangular versus butterfly resection in mitral valve repair for Barlow\u2019s disease"],"prefix":"10.4274","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0639-4341","authenticated-orcid":false,"given":"G\u00f6khan","family":"Laf\u00e7\u0131","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4675-3273","authenticated-orcid":false,"given":"\u00d6mer","family":"Faruk \u00c7i\u00e7ek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5526-5298","authenticated-orcid":false,"given":"Serkan","family":"Mola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1980-1302","authenticated-orcid":false,"given":"Emrah","family":"Ereren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3873-992X","authenticated-orcid":false,"given":"\u0130lker","family":"Hasan Karal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5837-1141","authenticated-orcid":false,"given":"H\u00fcseyin","family":"A\u011f\u0131rba\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3215-4114","authenticated-orcid":false,"given":"Ay\u015fe","family":"Laf\u00e7\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8642-8750","authenticated-orcid":false,"given":"G\u00f6ktan","family":"A\u015fk\u0131n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2075-0143","authenticated-orcid":false,"given":"Garip","family":"Alt\u0131nta\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2462-3168","authenticated-orcid":false,"given":"\u015eeref","family":"Alp K\u00fc\u00e7\u00fcker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2811","published-online":{"date-parts":[[2025,10,20]]},"reference":[{"key":"ref-1","doi-asserted-by":"crossref","unstructured":"van Wijngaarden AL, Kruithof BPT, Vinella T, BargeSchaapveld DQCM, Ajmone Marsan N. Characterization of degenerative mitral valve disease: Differences between fibroelastic deficiency and Barlow\u2019s disease. J Cardiovasc Dev Dis 2021;8:23. doi: 10.3390\/jcdd8020023.","DOI":"10.3390\/jcdd8020023"},{"key":"ref-2","doi-asserted-by":"crossref","unstructured":"Fornes P, Heudes D, Fuzellier JF, Tixier D, Bruneval P, Carpentier A. Correlation between clinical and histologic patterns of degenerative mitral valve insufficiency: A histomorphometric study of 130 excised segments. Cardiovasc Pathol 1999;8:81-92. doi: 10.1016\/s1054- 8807(98)00021-0.","DOI":"10.1016\/S1054-8807(98)00021-0"},{"key":"ref-3","doi-asserted-by":"crossref","unstructured":"Trent JK, Adelman AG, Wigle ED, Silver MD. Morphology of a prolapsed posterior mitral valve leaflet. 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J Thorac Cardiovasc Surg 1983;86:323-37.","DOI":"10.1016\/S0022-5223(19)39144-5"},{"key":"ref-7","doi-asserted-by":"crossref","unstructured":"Asai T, Kinoshita T, Nishimura O, Kambara A, Suzuki T, Matsubayashi K. A novel design of posterior leaflet butterfly resection for mitral valve repair. Innovations (Phila) 2011;6:54-6. doi: 10.1097\/IMI.0b013e31820c0107.","DOI":"10.1097\/imi.0b013e31820c0107"},{"key":"ref-8","doi-asserted-by":"crossref","unstructured":"Can T, Kirov H, Caldonazo T, Mukharyamov M, F\u00e4rber G, Doenst T. Surgical mitral valve repair technique considerations based on the available evidence. Turk Gogus Kalp Damar Cerrahisi Derg 2022;30:302-16. doi: 10.5606\/ tgkdc.dergisi.2022.23340.","DOI":"10.5606\/tgkdc.dergisi.2022.23340"},{"key":"ref-9","doi-asserted-by":"crossref","unstructured":"Carpentier A, Adams DH, Filsoufi F. Techniques in type II posterior leaflet prolapse. In: Carpentier A, Adams DH, Filsoufi F, editors. Carpentier\u2019s reconstructive valve surgery. Chapter 11. London: Elsevier Health Sciences; 2010. p. 117-8.","DOI":"10.1016\/B978-0-7216-9168-8.50006-X"},{"key":"ref-10","doi-asserted-by":"crossref","unstructured":"Carpentier A, Relland J, Deloche A, Fabiani JN, D'Allaines C, Blondeau P, et al. Conservative management of the prolapsed mitral valve. Ann Thorac Surg 1978;26:294-302. doi: 10.1016\/s0003-4975(10)62895-0.","DOI":"10.1016\/S0003-4975(10)62895-0"},{"key":"ref-11","doi-asserted-by":"crossref","unstructured":"Asai T, Kinoshita T, Hosoba S, Takashima N, Kambara A, Suzuki T, et al. Butterfly resection is safe and avoids systolic anterior motion in posterior leaflet prolapse repair. Ann Thorac Surg 2011;92:2097-102. doi: 10.1016\/j. athoracsur.2011.07.087.","DOI":"10.1016\/j.athoracsur.2011.07.087"},{"key":"ref-12","doi-asserted-by":"crossref","unstructured":"Asai T, Kinoshita T, Suzuki T, Shiraishi S, Koike M. Early and follow-up results of butterfly resection of prolapsed posterior leaflet in 76 consecutive patients. J Thorac Cardiovasc Surg 2015;149:1296-300. doi: 10.1016\/j.jtcvs.2015.01.001.","DOI":"10.1016\/j.jtcvs.2015.01.001"},{"key":"ref-13","doi-asserted-by":"crossref","unstructured":"Carpentier A, Adams DH, Filsoufi F. Techniques in type I dysfunction. In: Carpentier A, Adams DH, Filsoufi F, editors. Carpentier\u2019s reconstructive valve surgery. Chapter 8. London: Elsevier Health Sciences; 2010. p. 78-9.","DOI":"10.1016\/B978-0-7216-9168-8.50011-3"},{"key":"ref-14","doi-asserted-by":"crossref","unstructured":"Agricola E, Oppizzi M, Maisano F, Bove T, De Bonis M, Toracca L, et al. Detection of mechanisms of immediate failure by transesophageal echocardiography in quadrangular resection mitral valve repair technique for severe mitral regurgitation. Am J Cardiol 2003;91:175-9. doi: 10.1016\/ s0002-9149(02)03105-3.","DOI":"10.1016\/S0002-9149(02)03105-3"},{"key":"ref-15","doi-asserted-by":"crossref","unstructured":"Perier P, Hohenberger W, Lakew F, Batz G, Urbanski P, Zacher M, et al. Toward a new paradigm for the reconstruction of posterior leaflet prolapse: Midterm results of the \u201crespect rather than resect\u201d approach. Ann Thorac Surg 2008;86:718- 25. doi: 10.1016\/j.athoracsur.2008.05.015.","DOI":"10.1016\/j.athoracsur.2008.05.015"},{"key":"ref-16","doi-asserted-by":"crossref","unstructured":"Dreyfus GD, Dulguerov F, Marcacci C, Haley SR, Gkouma A, Dommerc C, et al. \u201cRespect when you can, resect when you should\u201d: A realistic approach to posterior leaflet mitral valve repair. J Thorac Cardiovasc Surg 2018;156:1856-66.e3. doi: 10.1016\/j.jtcvs.2018.05.017.","DOI":"10.1016\/j.jtcvs.2018.05.017"},{"key":"ref-17","doi-asserted-by":"crossref","unstructured":"Viani GM, Leo LA, Borruso MG, Klersy C, Paiocchi VL, Schlossbauer SA, et al. Mitral annulus morphometry in degenerative mitral regurgitation phenotypes. Echocardiography 2020;37:612-9. doi: 10.1111\/echo.14647.","DOI":"10.1111\/echo.14647"},{"key":"ref-18","doi-asserted-by":"crossref","unstructured":"Torii Y, Tani T, Okada T, Sano M, Nagano M, Hamano A, et al. Association of cardiovascular events between mitral annular disjunction and left atrial reservoir strain in Barlow's disease. 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