{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:12:43Z","timestamp":1785409963768,"version":"3.56.0"},"reference-count":16,"publisher":"Department of Medicine, Warren Alpert Medical School at Brown University","issue":"4","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>A 67-year-old man presented with joint swelling, muscular weakness, pain and anemia after the second dose of BNT162b2 (Pfizer-Biontech) mRNA COVID-19 vaccination. The signs and symptoms in the case met criteria for post-vaccination polymyalgia rheumatica (PMR) and Autoimmune\/Inflammatory Syndrome Induced by Adjuvants (ASIA) demonstrating the close association between these two conditions. The patient underwent a broad workup to rule out other causes and improved with corticosteroid therapy. Vaccine-associated autoimmune syndromes likely have heterogenous presentations and require a high index of suspicion to expedite recognition and treatment.<\/jats:p>","DOI":"10.56305\/001c.57060","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T09:32:21Z","timestamp":1671010341000},"source":"Crossref","is-referenced-by-count":0,"title":["Autoimmune\/Inflammatory Syndrome Induced by Adjuvants (ASIA) Following SARS-CoV2 Vaccination"],"prefix":"10.56305","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5893-3183","authenticated-orcid":false,"given":"Jasdeep Singh","family":"Bajwa","sequence":"first","affiliation":[{"name":"University of Rochester Medical Center, Rochester, NY, USA","department":["Department of Family Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery","family":"Harp","sequence":"additional","affiliation":[{"name":"University of Rochester Medical Center, Rochester, NY, USA","department":["Department of Family Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Mackenzie","sequence":"additional","affiliation":[{"name":"University of Rochester Medical Center, Rochester, NY, USA","department":["Department of Neurology and Neuromuscular Neurology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Thiele","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00trqv719","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Rochester Medical Center","department":["Department of Rheumatology and Immunology"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"35509","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"issue":"3","key":"ref1","doi-asserted-by":"publisher","first-page":"431","DOI":"10.3181\/00379727-156-39951","article-title":"Eosinophil response to alum adjuvants: involvement of T cells in non-antigen-dependent mechanisms","volume":"156","author":"R. 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