{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T16:03:54Z","timestamp":1789488234909,"version":"build-2803163510"},"reference-count":6,"publisher":"Department of Medicine, Warren Alpert Medical School at Brown University","issue":"3","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>\n                    Emphysematous cystitis is a life-threatening condition that can arise from complicated urinary tract infections. It is especially common in patients with poorly controlled diabetes mellitus. Common pathogens associated with this entity include\n                    <jats:italic>E. coli, K. pneumoniae, P. mirabilis,<\/jats:italic>\n                    among others. We present a case of a 69-year-old male with underlying benign prostatic hyperplasia and type II diabetes mellitus presenting with left-sided flank pain, nausea, gross hematuria, nausea, and vomiting. Computer tomography of the abdomen and pelvis revealed two large bladder stones (up to 4.5cm), trace intraluminal air in the bladder, and an enlarged prostate. Urine cultures grew Extended-Spectrum Beta-Lactamase (ESBL)\n                    <jats:italic>E. coli,<\/jats:italic>\n                    and the patient was treated with Ertapenem and management of underlying comorbidities. The patient was discharged after overall clinical status improvement.\n                  <\/jats:p>","DOI":"10.56305\/001c.77979","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T12:09:25Z","timestamp":1695038965000},"source":"Crossref","is-referenced-by-count":0,"title":["A Life-threatening Case of Emphysematous Cystitis with Large Bladder Stones"],"prefix":"10.56305","volume":"2","author":[{"given":"Jose Carlos","family":"Fernandez","sequence":"first","affiliation":[{"name":"HCA Florida Kendall Hospital","department":["Internal Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jackeline","family":"Porto","sequence":"additional","affiliation":[{"name":"HCA Florida Kendall Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Alvarez","sequence":"additional","affiliation":[{"name":"HCA Florida Kendall Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4281-8620","authenticated-orcid":false,"given":"Cinthia","family":"Reyes","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02m457w49","id-type":"ROR","asserted-by":"publisher"}],"name":"Pontificia Universidad Cat\u00f3lica Madre y Maestra","department":["School of Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"35509","published-online":{"date-parts":[[2023,7,1]]},"reference":[{"issue":"5","key":"ref1","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1111\/jdi.13398","article-title":"Effect of hypertriglyceridemia in dyslipidemia-induced impaired glucose tolerance and sex differences in dietary features associated with hypertriglyceridemia among the Japanese population: The Gifu Diabetes Study","volume":"12","author":"Yukiko Nonoyama","year":"2020","journal-title":"Journal of Diabetes Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/2040-1116","issn-type":"print"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.29651","article-title":"Emphysematous Pyelonephritis, Emphysematous Cystitis, and Emphysematous Ureteritis: A Case Report","author":"Jaime E Campos","year":"2022","journal-title":"Cureus","ISSN":"https:\/\/id.crossref.org\/issn\/2168-8184","issn-type":"print"},{"issue":"1","key":"ref3","doi-asserted-by":"publisher","first-page":"10","DOI":"10.3949\/ccjm.86a.18063","article-title":"Emphysematous cystitis","volume":"86","author":"Waiel Abusnina","year":"2019","journal-title":"Cleveland Clinic Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0891-1150","issn-type":"print"},{"issue":"2","key":"ref4","doi-asserted-by":"publisher","first-page":"129","DOI":"10.18926\/AMO\/45272","article-title":"Emphysematous cystitis in a patient with type 2 diabetes mellitus","volume":"65","author":"Noriko Toyota","year":"2011","journal-title":"Acta Medica Okayama"},{"key":"ref5","series-title":"Campbell-Walsh Urology","article-title":"103: Urinary Tract Infections and Pyelonephritis, Section 4: Special Conditions","author":"M.F. Campbell","year":"2007"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.11604\/pamj-cm.2020.3.113.23778","article-title":"Emphysematous cystitis complicated by bladder rupture: a paraplegic patient case","volume":"3","author":"Abdelghani Ouraghi","year":"2020","journal-title":"PAMJ Clinical Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/2707-2797","issn-type":"print"}],"container-title":["Journal of Brown Hospital Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bhm.scholasticahq.com\/article\/77979-a-life-threatening-case-of-emphysematous-cystitis-with-large-bladder-stones","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T15:18:16Z","timestamp":1789485496000},"score":1,"resource":{"primary":{"URL":"https:\/\/bhm.scholasticahq.com\/article\/77979-a-life-threatening-case-of-emphysematous-cystitis-with-large-bladder-stones"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,1]]},"references-count":6,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.56305\/001c.77979","relation":{},"ISSN":["2994-5593"],"issn-type":[{"value":"2994-5593","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,1]]}}}