{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:20:49Z","timestamp":1785421249693,"version":"3.56.0"},"reference-count":11,"publisher":"Department of Medicine, Warren Alpert Medical School at Brown University","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Pyoderma gangrenosum (PG) is a rare, inflammatory skin condition primarily characterized by painful ulcers with undermined borders, commonly occurring on the lower extremities. In approximately fifty percent of cases, PG is associated with underlying systemic diseases, including inflammatory bowel disease (IBD), inflammatory arthritis, or myeloproliferative disorders. PG is notorious for its variable clinical manifestations, which can closely resemble other dermatological conditions, often leading to misdiagnosis and inappropriate treatment. This case underscores the importance of including PG in the differential diagnosis for patients with ulcerative skin lesions to ensure prompt diagnosis and treatment. Furthermore, it highlights the necessity of screening for IBD in patients diagnosed with PG.<\/jats:p>","DOI":"10.56305\/001c.90522","type":"journal-article","created":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T07:26:47Z","timestamp":1704266807000},"source":"Crossref","is-referenced-by-count":0,"title":["Pyoderma Gangrenosum in Inflammatory Bowel Disease: A Rare Case Involving Mandibular, Elbow, and Pubic Ulcers"],"prefix":"10.56305","volume":"3","author":[{"given":"Alexandra","family":"Firek","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gz6gg07","id-type":"ROR","asserted-by":"publisher"}],"name":"Florida International University","department":["Herbert Wertheim College of Medicine"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey","family":"Warren","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00v47pv90","id-type":"ROR","asserted-by":"publisher"}],"name":"Baptist Health South Florida","department":["Florida International University-Family Medicine Residency Program"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4077-4181","authenticated-orcid":false,"given":"Carina","family":"Lorenzen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00v47pv90","id-type":"ROR","asserted-by":"publisher"}],"name":"Baptist Health South Florida","department":["Florida International University-Family Medicine Residency Program"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena P","family":"Bonilla MD","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02gz6gg07","id-type":"ROR","asserted-by":"publisher"}],"name":"Florida International University","department":["Herbert Wertheim College of Medicine"]},{"id":[{"id":"https:\/\/ror.org\/00v47pv90","id-type":"ROR","asserted-by":"publisher"}],"name":"Baptist Health South Florida","department":["Baptist Health Medical Group"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"35509","published-online":{"date-parts":[[2024,1,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"7247238","DOI":"10.1155\/2019\/7247238","article-title":"A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease","volume":"2019","author":"Qingdong Guan","year":"2019","journal-title":"Journal of Immunology Research","ISSN":"https:\/\/id.crossref.org\/issn\/2314-8861","issn-type":"print"},{"issue":"43","key":"ref2","doi-asserted-by":"publisher","first-page":"7577","DOI":"10.3748\/wjg.v19.i43.7577","article-title":"<i>Clostridium difficile<\/i>and inflammatory bowel disease: role in pathogenesis and implications in treatment","volume":"19","author":"Orna Nitzan","year":"2013","journal-title":"World Journal of Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/1007-9327","issn-type":"print"},{"issue":"6","key":"ref3","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1111\/j.1365-2133.2011.10565.x","article-title":"Pyoderma gangrenosum: a retrospective review of patient characteristics, comorbidities and therapy in 103 patients","volume":"165","author":"A.M. 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