{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T17:10:57Z","timestamp":1693933857547},"reference-count":0,"publisher":"Academy of Sciences and Arts of Bosnia and Herzegovina","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ama"],"abstract":"<jats:p>&lt;p&gt;&lt;strong&gt;Objective&lt;\/strong&gt;. Nasopharyngeal carcinoma is an extremely rare pediatric\u00a0malignancy predominantly occurring in adolescent males. Its multifactorial\u00a0pathogenesis is most strongly associated with the exposure to&lt;br \/&gt;Epstein-Barr virus in genetically susceptible hosts. In younger patients,\u00a0more aggressive biological behavior has been observed, although the\u00a0overall survival is better compared to adults. Due to its rarity and nonspecific\u00a0clinical presentation, the diagnosis in children is often delayed\u00a0and misinterpreted. &lt;strong&gt;Case report&lt;\/strong&gt;. We report a case of a 16-year-old\u00a0boy with stage IVB nasopharyngeal carcinoma. He presented with a\u00a0painless palpable neck mass, nasal congestion and a history of occasional\u00a0epistaxis and headaches. Four years after the completion of a\u00a0multimodal treatment, the patient is in complete remission. &lt;strong&gt;Conclusion&lt;\/strong&gt;.\u00a0Although exceedingly rare, pediatricians should consider nasopharyngeal\u00a0carcinoma in the differential diagnosis of palpable neck\u00a0masses, especially in male adolescents. A multidisciplinary approach\u00a0in the diagnosis, treatment, supportive care and follow-up is of utmost\u00a0importance.&lt;\/p&gt;<\/jats:p>","DOI":"10.5644\/ama2006-124.145","type":"journal-article","created":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T08:17:55Z","timestamp":1621325875000},"page":"186","source":"Crossref","is-referenced-by-count":1,"title":["Pediatric advanced stage nasopharyngeal carcinoma - case report"],"prefix":"10.5644","volume":"44","author":[{"given":"Jelena","family":"Roganovi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nu\u0161a","family":"Matija\u0161i\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mascarin","family":"Maurizio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"3666","published-online":{"date-parts":[[2015,12,18]]},"container-title":["Acta Medica Academica"],"original-title":[],"link":[{"URL":"http:\/\/www.ama.ba\/index.php\/ama\/article\/viewFile\/261\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T08:18:36Z","timestamp":1621325916000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.ama.ba\/index.php\/ama\/article\/view\/261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,18]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2015,12,18]]}},"URL":"https:\/\/doi.org\/10.5644\/ama2006-124.145","relation":{},"ISSN":["1840-2879","1840-1848"],"issn-type":[{"value":"1840-2879","type":"electronic"},{"value":"1840-1848","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12,18]]}}}