{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:30:35Z","timestamp":1792009835232,"version":"4.4.0"},"reference-count":30,"publisher":"Japan Oil Chemists' Society","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Oleo Sci."],"published-print":{"date-parts":[[2023]]},"DOI":"10.5650\/jos.ess23065","type":"journal-article","created":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T22:28:04Z","timestamp":1694471284000},"page":"929-938","source":"Crossref","is-referenced-by-count":4,"title":["Selenium-enriched Polysaccharides from <i>Pyracantha fortuneana<\/i> (SePFP) Ameliorated Hepatic Lipid Accumulation through Enhancing Mitochondrial Fatty Acid \u03b2-Oxidation in Aging Mice"],"prefix":"10.5650","volume":"72","author":[{"given":"Yaqi","family":"Hu","sequence":"first","affiliation":[{"name":"College of Basic Medical Science, China Three Gorges University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Basic Medical Science, China Three Gorges University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuwen","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Basic Medical Science, China Three Gorges University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengfu","family":"Yuan","sequence":"additional","affiliation":[{"name":"College of Basic Medical Science, China Three Gorges University"},{"name":"Hubei Provincial Clinical Research Center for Precise Prevention and Treatment of Elderly Gastrointestinal Cancer, The Second People\u2019s Hospital of China Three Gorges University,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Yuan","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Science, China Three Gorges University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Basic Medical Science, China Three Gorges University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxia","family":"Ren","sequence":"additional","affiliation":[{"name":"Hubei Provincial Clinical Research Center for Precise Prevention and Treatment of Elderly Gastrointestinal Cancer, The Second People\u2019s Hospital of China Three Gorges University,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumin","family":"He","sequence":"additional","affiliation":[{"name":"College of Medicine and Health Science, China Three Gorges University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoshan","family":"Wu","sequence":"additional","affiliation":[{"name":"Chongqing Redjoy Health Industry (Group) Co., Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjun","family":"Dai","sequence":"additional","affiliation":[{"name":"Chongqing Redjoy Health Industry (Group) Co., Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyong","family":"Wang","sequence":"additional","affiliation":[{"name":"Chongqing Redjoy Health Industry (Group) Co., Ltd."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijun","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The Second People\u2019s Hospital of Wufeng Tujia Autonomous County"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3621","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1) Vaiserman, A.M.; Koliada, A.K.; Marotta, F. Gut microbiota: A player in aging and a target for anti-aging intervention. Ageing Res. Rev. 35, 36-45 (2017).","DOI":"10.1016\/j.arr.2017.01.001"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) O\u2019toole, P.W.; Jeffery, I.B. Microbiome-health interactions in older people. Cell. Mol. Life Sci. 75, 119-128 (2018).","DOI":"10.1007\/s00018-017-2673-z"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Gardner, I.D. The effect of aging on susceptibility to infection. Rev. Infect. Dis. 2, 801-810 (1980).","DOI":"10.1093\/clinids\/2.5.801"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Forni, C.; Facchiano, F.; Bartoli, M.; Pieretti, S.; Facchiano, A. et al. Beneficial role of phytochemicals on oxidative stress and age-related diseases. Biomed. Res. Int. 2019, 8748253 (2019).","DOI":"10.1155\/2019\/8748253"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Gimeno-Mallench, L.; Mas-Bargues, C.; Ingl\u00e9s, M.; Olaso, G.; Borras, C. et al. Resveratrol shifts energy metabolism to increase lipid oxidation in healthy old mice. Biomed. Pharmacother. 118, 109130 (2019).","DOI":"10.1016\/j.biopha.2019.109130"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Xu, M.; Pirtskhalava, T.; Farr, J.N.; Weigand, B.M.; Palmer, A.K. et al. Senolytics improve physical function and increase lifespan in old age. Nat. Med. 24, 1246-1256 (2018).","DOI":"10.1038\/s41591-018-0092-9"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Frank, A.P.; De Souza Santos, R.; Palmer, B.F.; Clegg, D.J. Determinants of body fat distribution in humans may provide insight about obesity-related health risks. J. Lipid Res. 60, 1710-1719 (2019).","DOI":"10.1194\/jlr.R086975"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Wang, S.; Ren, J. Obesity paradox in aging: From prevalence to pathophysiology. Prog. Cardiovasc. Dis. 61, 182-189 (2018).","DOI":"10.1016\/j.pcad.2018.07.011"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Filip, R.; Radzki, R.P.; Bie\u0144ko, M. Novel insights into the relationship between nonalcoholic fatty liver disease and osteoporosis. Clin. Interv. Aging 13, 1879-1891 (2018).","DOI":"10.2147\/CIA.S170533"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Cree, M.G.; Newcomer, B.R.; Katsanos, C.S.; Sheffield-Moore, M.; Chinkes, D. et al. Intramuscular and liver triglycerides are increased in the elderly. J. Clin. Endocrinol. Metab. 89, 3864-3871 (2004).","DOI":"10.1210\/jc.2003-031986"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Fan, J.-G.; Zhu, J.; Li, X.-J.; Chen, L.; Li, L. et al. Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J. Hepatol. 43, 508-514 (2005).","DOI":"10.1016\/j.jhep.2005.02.042"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Gong, Z.; Tas, E.; Yakar, S.; Muzumdar, R. Hepatic lipid metabolism and non-alcoholic fatty liver disease in aging. Mol. Cell. Endocrinol. 455, 115-130 (2017).","DOI":"10.1016\/j.mce.2016.12.022"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Xie, J.-H.; Jin, M.-L.; Morris, G.A.; Zha, X.-Q.; Chen, H.-Q. et al. Advances on bioactive polysaccharides from medicinal plants. Crit. Rev. Food Sci. Nutr. 56 (Suppl. 1), S60-S84 (2016).","DOI":"10.1080\/10408398.2015.1069255"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Sun, Y.; Liang, H.; Cai, G.; Guan, S.; Tong, H. et al. Sulfated modification of the water-soluble polysaccharides from Polyporus albicans mycelia and its potential biological activities. Int. J. Biol. Macromol. 44, 14-17 (2009).","DOI":"10.1016\/j.ijbiomac.2008.09.010"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Rayman, M.P. The importance of selenium to human health. Lancet 356, 233-241 (2000).","DOI":"10.1016\/S0140-6736(00)02490-9"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Schrauzer, G.N. Nutritional selenium supplements: Product types, quality, and safety. J. Am. Coll. Nutr. 20, 1-4 (2001).","DOI":"10.1080\/07315724.2001.10719007"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Zapletal, C.; Heyne, S.; Breitkreutz, R.; Gebhard, M.-M.; Golling, M. The influence of selenium substitution on microcirculation and glutathione metabolism after warm liver ischemia\/reperfusion in a rat model. Microvasc. Res. 76, 104-109 (2008).","DOI":"10.1016\/j.mvr.2008.04.005"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Yuan, C.; Li, Z.; Yi, M.; Wang, X.; Peng, F. et al. Effects of polysaccharides from selenium-enriched Pyracantha fortuneana on mice liver injury. Med. Chem. 11, 780-788 (2015).","DOI":"10.2174\/1573406411666150602153357"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Peng, F.; Guo, X.; Li, Z.; Li, C.; Wang, C. et al. Antimutagenic effects of selenium-enriched polysaccharides from Pyracantha fortuneana through suppression of cytochrome P450 1A subfamily in the mouse liver. Molecules 21, 1731 (2016).","DOI":"10.3390\/molecules21121731"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Sun, Q.; Dong, M.; Wang, Z.; Wang, C.; Sheng, D. et al. Selenium-enriched polysaccharides from Pyracantha fortuneana (Se-PFPs) inhibit the growth and invasive potential of ovarian cancer cells through inhibiting \u03b2-catenin signaling. Oncotarget 7, 28369-28383 (2016).","DOI":"10.18632\/oncotarget.8619"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Yuan, C.; Wang, C.; Wang, J.; Kumar, V.; Anwar, F. et al. Inhibition on the growth of human MDA-MB-231 breast cancer cells in vitro and tumor growth in a mouse xenograft model by Se-containing polysaccharides from Pyracantha fortuneana. Nutr. Res. 36, 1243-1254 (2016).","DOI":"10.1016\/j.nutres.2016.09.012"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Yuan, C.; Li, Z.; Peng, F.; Xiao, F.; Ren, D. et al. Combination of selenium-enriched green tea polysaccharides and Huo-ji polysaccharides synergistically enhances antioxidant and immune activity in mice. J. Sci. Food Agric. 95, 3211-3217 (2015).","DOI":"10.1002\/jsfa.7287"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Wang, Q.; Jiang, L.; Wang, J.; Li, S.; Yu, Y. et al. Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. Hepatology 49, 1166-1175 (2009).","DOI":"10.1002\/hep.22774"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Longo, K.A.; Charoenthongtrakul, S.; Giuliana, D.J.; Govek, E.K.; Mcdonagh, T. et al. The 24-hour respiratory quotient predicts energy intake and changes in body mass. Am. J. Physiol. Regul. Integr. Comp. Physiol. 298, R747-R754 (2010).","DOI":"10.1152\/ajpregu.00476.2009"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) H\u00e4nfling, B.; Lawson Handley, L.; Read, D.S.; Hahn, C.; Li, J. et al. Environmental DNA metabarcoding of lake fish communities reflects long-term data from established survey methods. Mol. Ecol. 25, 3101-3119 (2016).","DOI":"10.1111\/mec.13660"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Wesselink, E.; Koekkoek, W.a.C.; Grefte, S.; Witkamp, R.F.; Van Zanten, A.R.H. Feeding mitochondria: Potential role of nutritional components to improve critical illness convalescence. Clin. Nutr. 38, 982-995 (2019).","DOI":"10.1016\/j.clnu.2018.08.032"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Kim, J.E.; Choi, S.I.; Lee, H.R.; Hwang, I.S.; Lee, Y.J. et al. Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid \u03b2-oxidation. Biol. Trace Elem. Res. 150, 360-370 (2012).","DOI":"10.1007\/s12011-012-9519-1"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Yao, Y.-L.; Shu, C.; Feng, G.; Wang, Q.; Yan, Y.-Y. et al. Polysaccharides from Pyracantha fortuneana and its biological activity. Int. J. Biol. Macromol. 150, 1162-1174 (2020).","DOI":"10.1016\/j.ijbiomac.2019.10.125"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Bonz\u00f3n-Kulichenko, E.; Molt\u00f3, E.; Pintado, C.; Fern\u00e1ndez, A.; Arribas, C. et al. Changes in visceral adipose tissue plasma membrane lipid composition in old rats are associated with adipocyte hypertrophy with aging. J. Gerontol. A Biol. Sci. Med. Sci. 73, 1139-1146 (2018).","DOI":"10.1093\/gerona\/gly081"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Gai, H.; Zhou, F.; Zhang, Y.; Ai, J.; Zhan, J. et al. Coniferaldehyde ameliorates the lipid and glucose metabolism in palmitic acid-induced HepG2 cells via the LKB1\/AMPK signaling pathway. J. Food Sci. 85, 4050-4060 (2020).","DOI":"10.1111\/1750-3841.15482"}],"container-title":["Journal of Oleo Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jos\/72\/10\/72_ess23065\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T04:54:40Z","timestamp":1715576080000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jos\/72\/10\/72_ess23065\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.5650\/jos.ess23065","relation":{},"ISSN":["1345-8957","1347-3352"],"issn-type":[{"value":"1345-8957","type":"print"},{"value":"1347-3352","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]},"article-number":"ess23065"}}