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Nanotechnology: An Introduction, William Andrew (2016).","DOI":"10.1016\/B978-0-323-39311-9.00017-0"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Albrecht, M.A.; Evans, C.W; Raston, C.L. Green chemistry and the health implications of nanoparticles. Green Chem. 8, 417-432 (2006).","DOI":"10.1039\/b517131h"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Herlekar, M.; Barve, S; Kumar, R. Plant-mediated green synthesis of iron nanoparticles. J. Nanopart. 2014, 140614 (2014).","DOI":"10.1155\/2014\/140614"},{"key":"4","unstructured":"4) Simonis, F; Schilthuizen, S. Nanotechnology; Innovation Opportunities for Tomorrow\u2019s Defence. TNO Science &amp; Industry Future Technology Center, The Netherlands (2006)."},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Iravani, S. Green synthesis of metal nanoparticles using plants. Green Chem. 13, 2638-2650 (2011).","DOI":"10.1039\/c1gc15386b"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Duan, H.; Wang, D; Li, Y. Green chemistry for nanoparticle synthesis. Chem. Soc. Rev. 44, 5778-5792 (2015).","DOI":"10.1039\/C4CS00363B"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Bala, N.; Saha, S.; Chakraborty, M.; Maiti, M.; Das, S. et al. Green synthesis of zinc oxide nanoparticles using Hibiscus subdariffa leaf extract: Effect of temperature on synthesis, anti-bacterial activity and anti-diabetic activity. RSC Adv. 5, 4993-5003 (2015).","DOI":"10.1039\/C4RA12784F"},{"key":"8","unstructured":"8) Hasan, S.A. Review on nanoparticles: Their synthesis and types. Res. J. Recent Sci. 4, 1-3 (2015)."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Barzinjy, A.A.; Hamad, S.M.; Ayd\u0131n, S.; Ahmed, M.H; Hussain, F.H. Green and eco-friendly synthesis of nickel oxide nanoparticles and its photocatalytic activity for methyl orange degradation. J. Mater. Sci. Mater. Electron. 31, 11303-11316 (2020).","DOI":"10.1007\/s10854-020-03679-y"},{"key":"10","unstructured":"10) Altavilla, C; Ciliberto, E. in Inorganic Nanoparticles: Synthesis, Applications, and Perspectives. An Overview (Altavilla, C.; Ciliberto, E. eds.), CRC Press, New York, pp 1-17 (2011)."},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Al-Naamani, L.; Dobretsov, S; Dutta, J. Chitosan-zinc oxide nanoparticle composite coating for active food packaging applications. Innov. Food Sci. Emerg. Technol. 38, 231-237 (2016).","DOI":"10.1016\/j.ifset.2016.10.010"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Sankapal, B.R.; Gajare, H.B.; Karade, S.S.; Salunkhe, R.R; Dubal, D.P. Zinc oxide encapsulated carbon nanotube thin films for energy storage applications. Electrochim. Acta 192, 377-384 (2016).","DOI":"10.1016\/j.electacta.2016.01.193"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13) Kumar, R.; Al-Dossary, O.; Kumar, G; Umar, A. Zinc oxide nanostructures for NO<sub>2<\/sub> gas\u2013sensor applications: A review. Nano-Micro Lett. 7, 97-120 (2015).","DOI":"10.1007\/s40820-014-0023-3"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Kumar, S.G; and Rao, K.K. Zinc oxide based photocatalysis: Tailoring surface-bulk structure and related interfacial charge carrier dynamics for better environmental applications. RSC Adv. 5, 3306-3351 (2015).","DOI":"10.1039\/C4RA13299H"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Hatamie, A.; Khan, A.; Golabi, M.; Turner, A.P.; Beni, V. et al. Zinc oxide nanostructure-modified textile and its application to biosensing, photocatalysis, and as antibacterial material. Langmuir 31, 10913-10921 (2015).","DOI":"10.1021\/acs.langmuir.5b02341"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Mishra, P.K.; Mishra, H.; Ekielski, A.; Talegaonkar, S; Vaidya, B. Zinc oxide nanoparticles: A promising nanomaterial for biomedical applications. Drug Discovery Today 22, 1825-1834 (2017).","DOI":"10.1016\/j.drudis.2017.08.006"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Nagajyothi, P.; Cha, S.J.; Yang, I.J.; Sreekanth, T.; Kim, K.J; Shin, H.M. Antioxidant and anti-inflammatory activities of zinc oxide nanoparticles synthesized using Polygala tenuifolia root extract. J. Photochem. Photobiol. B 146, 10-17 (2015).","DOI":"10.1016\/j.jphotobiol.2015.02.008"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Cai, X.; Luo, Y.; Zhang, W.; Du, D; Lin, Y. pH-Sensitive ZnO quantum dots\u2013doxorubicin nanoparticles for lung cancer targeted drug delivery. ACS Appl. Mater. Interfaces 8, 22442-22450 (2016).","DOI":"10.1021\/acsami.6b04933"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Gutha, Y.; Pathak, J.L.; Zhang, W.; Zhang, Y; Jiao, X. Antibacterial and wound healing properties of chitosan\/poly (vinyl alcohol) \/zinc oxide beads (CS\/PVA\/ZnO). Int. J. Biol. Macromol. 103, 234-241 (2017).","DOI":"10.1016\/j.ijbiomac.2017.05.020"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Lai, L.; Zhao, C.; Su, M.; Li, X.; Liu, X. et al. In vivo target bio-imaging of Alzheimer\u2019s disease by fluorescent zinc oxide nanoclusters. Biomater. Sci. 4, 1085-1091 (2016).","DOI":"10.1039\/C6BM00233A"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Lammers, T.; Sofias, A.M.; van der Meel, R.; Schiffelers, R.; Gert, S. et al. Dexamethasone nanomedicines for COVID-22. Nat. Nanotechnol. 15, 622-624 (2020).","DOI":"10.1038\/s41565-020-0752-z"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Zhang, P.; Zhang, Y.; Ding, X.; Shen, W.; Li, M. et al. A multistage cooperative nanoplatform enables intracellular co-delivery of proteins and chemotherapeutics for cancer therapy. Adv. Mater. 32, e2000013 (2020).","DOI":"10.1002\/adma.202000013"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Li, J.; Jia, Y.; Zhang, P.; Yang, H.; Cong, X. et al. Celastrol self-stabilized nanoparticles for effective treatment of melanoma. Int. J. Nanomedicine 15, 1205-1214 (2020).","DOI":"10.2147\/IJN.S232603"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) de Oliveira, M.T.P.; de Sa Coutinho, D.; Tenorio de Souza, E.; Stanis\u00e7uaski Guterres, S.; Pohlmann, A.R. et al. Orally delivered resveratrol-loaded lipid-core nanocapsules ameliorate LPS-induced acute lung injury via the ERK and PI3K\/Akt pathways. Int. J. Nanomedicine 14, 5215-5228 (2019).","DOI":"10.2147\/IJN.S200666"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Zhang, C.Y.; Lin, W.; Gao, J.; Shi, X.; Davaritouchaee, M. et al. pH-Responsive nanoparticles targeted to lungs for improved therapy of acute lung inflammation\/injury. ACS Appl. Mater. Interfaces 11, 16380-16390 (2019).","DOI":"10.1021\/acsami.9b04051"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Jin, F.; Liu, D.; Yu, H.; Qi, J.; You, Y. et al. Sialic acid-functionalized PEG-PLGA microspheres loading mitochondrial-targeting-modified curcumin for acute lung injury therapy. Mol. Pharm. 16, 71-85 (2019).","DOI":"10.1021\/acs.molpharmaceut.8b00861"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Wang, M.; Wang, K.; Deng, G.; Li, X.; Wu, X. et al. Mitochondria-modulating porous Se@SiO<sub>2<\/sub> nanoparticles provide resistance to oxidative injury in airway epithelial cells: Implications for acute lung injury. Int. J. Nanomedicine 15, 2287-2302 (2020).","DOI":"10.2147\/IJN.S240301"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28) Wang, L.; Zhang, H.; Sun, L.; Gao, W.; Xiong, Y. et al. Manipulation of macrophage polarization by peptide-coated gold nanoparticles and its protective effects on acute lung injury. J. Nanobiotechnology 18, 38 (2020).","DOI":"10.1186\/s12951-020-00593-7"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Dos Santos Haupenthal, D.P.; Mendes, C.; de Bem Silveira, G.; Zaccaron, R.P.; Corr\u00eaa, M.E.A.B. et al. Effects of treatment with gold nanoparticles in a model of acute pulmonary inflammation induced by lipopolysaccharide. J. Biomed. Mater. Res. A 108, 103-115 (2020).","DOI":"10.1002\/jbm.a.36796"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Gao, W.; Wang, Y.; Xiong, Y.; Sun, L.; Wang, L. et al. Size-dependent anti-inflammatory activity of a peptide-gold nanoparticle hybrid in vitro and in a mouse model of acute lung injury. Acta Biomater. 85, 203-217 (2019).","DOI":"10.1016\/j.actbio.2018.12.046"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) Yu. H.P.; Liu, F.C.; Umoro, A.; Lin, Z.C.; Elzoghby, A.O. et al. Oleic acid-based nanosystems for mitigating acute respiratory distress syndrome in mice through neutrophil suppression: how the particulate size affects therapeutic efficiency. J. Nanobiotechnology 18, 25 (2020).","DOI":"10.1186\/s12951-020-0583-y"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Okeke, E.B.; Louttit, C.; Fry, C.; Najafabadi, A.H.; Han, K. et al. Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock. Biomaterials 238, 119836 (2020).","DOI":"10.1016\/j.biomaterials.2020.119836"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33) Liu, F.C.; Yu, H.P.; Lin, C.Y.; Elzoghby, A.O.; Hwang, T.L; Fang, J.Y. Use of cilomilast-loaded phosphatiosomes to suppress neutrophilic inflammation for attenuating acute lung injury: The effect of nanovesicular surface charge. J. Nanobiotechnology 16, 35 (2018).","DOI":"10.1186\/s12951-018-0364-z"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Jiang, S.; Li, S.; Hu, J.; Xu, X.; Wang, X. et al. Combined delivery of angiopoietin-1 gene and simvastatin mediated by anti-intercellular adhesion molecule-1 antibody-conjugated ternary nanoparticles for acute lung injury therapy. Nanomedicine 15, 25-36 (2019).","DOI":"10.1016\/j.nano.2018.08.009"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Ge, C.; Yang, J.; Duan, S.; Liu, Y.; Meng, F; Yin, L. Fluorinated alpha-helical polypeptides synchronize mucus permeation and cell penetration toward highly efficient pulmonary siRNA delivery against acute lung injury. Nano Lett. 20, 1738-1746 (2020).","DOI":"10.1021\/acs.nanolett.9b04957"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36) Piao, C.; Zhuang, C.; Choi, M.; Ha, J; Lee, M. A RAGE-antagonist peptide potentiates polymeric micelle-mediated intracellular delivery of plasmid DNA for acute lung injury gene therapy. Nanoscale 12, 13606-13617 (2020).","DOI":"10.1039\/D0NR01367F"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) Lowry, O.H.; Rosebrough, N.J.; Farr, A.L; Randall, R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265\u201175 (1951).","DOI":"10.1016\/S0021-9258(19)52451-6"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38) Wang, H; Joseph, J.A. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic. Biol. Med. 27, 612\u2011616 (1999).","DOI":"10.1016\/S0891-5849(99)00107-0"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39) Ohkawa, H.; Ohishi, N; Yagi, K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95, 351\u2011358 (1979).","DOI":"10.1016\/0003-2697(79)90738-3"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40) Ellman, G.L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82, 70\u201177 (1959).","DOI":"10.1016\/0003-9861(59)90090-6"},{"key":"41","doi-asserted-by":"crossref","unstructured":"41) Zahler, W.L; Cleland, W.W. A specific and sensitive assay for disulfides. J. Biol. Chem. 243, 716\u2011719 (1968).","DOI":"10.1016\/S0021-9258(19)81724-6"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42) Aebi, H. Catalase in vitro. Methods Enzymol. 105, 121\u2011126 (1984).","DOI":"10.1016\/S0076-6879(84)05016-3"},{"key":"43","doi-asserted-by":"crossref","unstructured":"43) Sasani Ghamsari, M.; Alamdari, S.; Han, W; Park, H. Impact of nanostructured thin ZnO film in ultraviolet protection. Int. J. Nanomed. 12, 207-216 (2016).","DOI":"10.2147\/IJN.S118637"},{"key":"44","doi-asserted-by":"crossref","unstructured":"44) Tan, S.T.; Chen, B.J.; Sun, X.W.; Fan, W.J.; Kwok, H.S. et al. Blueshift of optical band gap in ZnO thin films grown by metal-organic chemicalvapor deposition. J. Appl. Phys. 98, 013505 (2005).","DOI":"10.1063\/1.1940137"},{"key":"45","doi-asserted-by":"crossref","unstructured":"45) Debanath, M.K; Karmakar, S. Study of blueshift of optical band gap in zinc oxide (ZnO) nanoparticles prepared by low-temperature wet chemical method. Mater. Lett. 11, 116-119 (2013).","DOI":"10.1016\/j.matlet.2013.08.069"},{"key":"46","unstructured":"46) Chen, C.; Yu, B.; Liu, P.; Liu, J; Wang, L. Investigation of nano-sized ZnO particles fabricated by various synthesis routes. J. Ceram. Process. Res. 12, 420-425 (2011)."},{"key":"47","doi-asserted-by":"crossref","unstructured":"47) Lu, J.; Batjikh, I.; Hurh, J.; Han, Y.; Ali, H. et al. Photocatalytic degradation of methylene blue using biosynthesized zinc oxide nanoparticles from bark extract of Kalopanax septemlobus. Optik 182, 980-985 (2019).","DOI":"10.1016\/j.ijleo.2018.12.016"},{"key":"48","doi-asserted-by":"crossref","unstructured":"48) Comhair, S.A; Erzurum, S.C. Antioxidant responses to oxidant\u2011mediated lung diseases. Am. J. Physiol. Lung Cell. Mol. Physiol. 283, L246\u201155 (2002).","DOI":"10.1152\/ajplung.00491.2001"},{"key":"49","doi-asserted-by":"crossref","unstructured":"49) Birben, E.; Sahiner, U.M.; Sackesen, C.; Erzurum, S; Kalayci, O. Oxidative stress and antioxidant defense. World Allergy Organ. 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