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IDF diabetes Atlas: Global estimates of undiagnosed diabetes in adults for 2021. Diabetes Res. Clin. Pract. 183, 109118 (2022).","DOI":"10.1016\/j.diabres.2021.109118"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2) Bhattacharjee, N.; Barma, S.; Konwar, N.; Dewanjee, S.; Manna, P. Mechanistic insight of diabetic nephropathy and its pharmacotherapeutic targets: An update. Eur. J. Pharmacol. 791, 8-24 (2016).","DOI":"10.1016\/j.ejphar.2016.08.022"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3) Humphreys, B.D. Mechanisms of renal fibrosis. Annu. Rev. Physiol. 80, 309-326 (2018).","DOI":"10.1146\/annurev-physiol-022516-034227"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4) Lee, E.Y.; Kim, G.T.; Hyun, M.; Kim, S.; Seok, S. et al. Peroxisome proliferator-activated receptor-delta activation ameliorates albuminuria by preventing nephrin loss and restoring podocyte integrity in type 2 diabetes. Nephrol. Dial. Transplant. 27, 4069-4079 (2012).","DOI":"10.1093\/ndt\/gfs358"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5) Kang, M.K.; Kim, S.I.; Oh, S.Y.; Na, W.; Kang, Y.H. Tangeretin ameliorates glucose-induced podocyte injury through blocking epithelial to mesenchymal transition caused by oxidative stress and hypoxia. Int. J. Mol. Sci. 21, 8577 (2020).","DOI":"10.3390\/ijms21228577"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Hidayat, R.; Wulandari, P. Effects of Andrographis paniculata (Burm. F.) extract on diabetic nephropathy in rats. Rep. Biochem. Mol. Biol. 10, 445-454 (2021).","DOI":"10.52547\/rbmb.10.3.445"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7) Tavafi, M. Diabetic nephropathy and antioxidants. J. Nephropathol. 2, 20-27 (2013).","DOI":"10.5812\/nephropathol.9093"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8) Donate-Correa, J.; Luis-Rodr\u00edguez, D.; Mart\u00edn-N\u00fa\u00f1ez, E.; Tagua, V.G.; Hern\u00e1ndez-Carballo, C. et al. Inflammatory targets in diabetic nephropathy. J. Clin. Med. 9, 458 (2020).","DOI":"10.3390\/jcm9020458"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Thallas-Bonke, V.; Thorpe, S.R.; Coughlan, M.T.; Fukami, K.; Yap, F.Y.T. et al. Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-\u03b1-dependent pathway. Diabetes 57, 460-469 (2008).","DOI":"10.2337\/db07-1119"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Kao, M.P.; Ang, D.S.; Pall, A.; Struthers, A.D. Oxidative stress in renal dysfunction: Mechanisms, clinical sequelae and therapeutic options. J. Hum. Hypertens. 24, 1-8 (2010).","DOI":"10.1038\/jhh.2009.70"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11) Daisy, P.; Saipriya, K. Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus. Int. J. Nanomed. 7, 1189-1202 (2012).","DOI":"10.2147\/IJN.S26650"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12) Deng, W.; Wang, H.; Wu, B.; Zhang, X. Selenium-layered nanoparticles serving for oral delivery of phytomedicines with hypoglycemic activity to synergistically potentiate the antidiabetic effect. Acta Pharm. Sin. B 9, 74-86 (2019).","DOI":"10.1016\/j.apsb.2018.09.009"},{"key":"13","unstructured":"13) Edrees, H.M.; Elbehiry, A.; Elmosaad, Y.M. Hypoglycemic and anti-inflammatory effect of gold nanoparticles in streptozotocin-induced type 1 diabetes in experimental rats. Int. J. Diabetes Res. 6, 16-23 (2017)."},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Manna, K.; Mishra, S.; Saha, M.; Mahapatra, S.; Saha, C. et al. Amelioration of diabetic nephropathy using pomegranate peel extract-stabilized gold nanoparticles: assessment of NF-\u03baB and Nrf2 signaling system. Int. J. Nanomed. 14, 1753-1777 (2019).","DOI":"10.2147\/IJN.S176013"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Rizwan, H.; Mohanta, J.; Si, S.; Pal, A. Gold nanoparticles reduce high glucose-induced oxidative-nitrosative stress regulated inflammation and apoptosis via tuberin-mTOR\/NF-\u03baB pathways in macrophages. Int. J. Nanomed. 12, 5841-5862 (2017).","DOI":"10.2147\/IJN.S141839"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Garcia, C.A.H.; Perez, G.R.M.; Manriquez-Alvirde, G.; Mu\u00f1iz, R.A. Protection of silver nanoparticles using Eysenhardtia polystachya in peroxide-induced pancreatic \u03b2-Cell damage and their antidiabetic properties in zebrafish. Int. J. Nanomed. 13, 2601-2612 (2018).","DOI":"10.2147\/IJN.S163714"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Atale, N.; Saxena, S.; Nirmala, J.G.; Narendhirakannan, R.T.; Mohanty, S.; Rani, V. Synthesis and characterization of Sygyzium cumini nanoparticles for its protective potential in high glucose-induced cardiac stress: a green approach. Appl. Biochem. Biotechnol. 181, 1140-1154 (2017).","DOI":"10.1007\/s12010-016-2274-6"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) Jini, D.; Sharmila, S. Green synthesis of silver nanoparticles from Allium cepa and its in vitro antidiabetic activity. Mater. Today Proc. 22, 432-438 (2020).","DOI":"10.1016\/j.matpr.2019.07.672"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19) Kotaru, M.; Korimelli, S. Evaluation of anti-diabetic activity of silver nanoparticles synthesized from ethanolic extract of Phyllanthus niruri on wistar rats. J. Drug Deliv. Ther. 13 (6), 83-88 (2023).","DOI":"10.22270\/jddt.v13i6.6098"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20) Tang, F.; Mahdavi, B. Protective properties of AgNPs green-synthesized by Abelmoschus esculentus on retinal damage on the virtue of its anti-inflammatory and antioxidant effects in diabetic rat. Open Chemistry 21, 20230138 (2023).","DOI":"10.1515\/chem-2023-0138"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21) Raafat, K.; Habib, J. Phytochemical compositions and antidiabetic potentials of Salvia sclarea L. essential oils. J. Oleo Sci. 67, 1015-025 (2018).","DOI":"10.5650\/jos.ess17187"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22) Zengin, G.; Senkardes, I.; Mollica, A.; Picot-Allain, C.M.N.; Bulut, G. et al. New insights into the in vitro biological effects, in silico docking and chemical profile of clary sage\u2014Salvia sclarea L. Comput. Biol. Chem. 75, 111-119 (2018).","DOI":"10.1016\/j.compbiolchem.2018.05.005"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23) Zhou, J.; Xie, X.; Tang, H.; Peng, C.; Peng, F. The bioactivities of sclareol: A mini review. Front. Pharmacol. 13, 1014105 (2022).","DOI":"10.3389\/fphar.2022.1014105"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24) Trinder, P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann. Clin. Biochem. 6, 24-27 (1969).","DOI":"10.1177\/000456326900600108"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Baker, J.R.; Metcalf, P.A.; Holdaway, I.M.; Johnson, R.N. Serum fructosamine concentration as measure of blood glucose control in type I (insulin dependent) diabetes mellitus. Br. Med. J. (Clin Res Ed). 290, 352-355 (1985).","DOI":"10.1136\/bmj.290.6465.352"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26) Abraham, E.C.; Huff, T.A.; Cope, N.D.; Wilson, J.B.Jr.; Bransome, E.D.Jr.; Huisman, T.H. Determination of the glycosylated hemoglobins (HB AI) with a new microcolumn procedure. Suitability of the technique for assessing the clinical management of diabetes mellitus. Diabetes 27, 931-937 (1978).","DOI":"10.2337\/diab.27.9.931"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27) Preuss, H.G.; Jarrell, S.T.; Scheckenbach, R.; Lieberman, S.; Anderson, R.A. Comparative effects of chromium, vanadium and gymnema sylvestre on sugar-induced blood pressure elevations in SHR. J. Am. Coll. Nutr. 17, 116-123 (1998).","DOI":"10.1080\/07315724.1998.10718736"},{"key":"28","unstructured":"28) Beutler, E.; Duron, O.; Kelly, B.M. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 61, 882-888 (1963)."},{"key":"29","doi-asserted-by":"crossref","unstructured":"29) Cohen, G.; Dembiec, D.; Marcus, J. Measurement of catalase activity in tissue extracts. Anal. Biochem. 34, 30-38 (1970).","DOI":"10.1016\/0003-2697(70)90083-7"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) Marklund, S.; Marklund, G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. FEBS Eur. J. Biochem. 47, 469-474 (1974).","DOI":"10.1111\/j.1432-1033.1974.tb03714.x"},{"key":"31","unstructured":"31) Matkovics, B.; Szabo, L.; Varga, I.S. Determination of enzyme activities in lipid peroxidation and glutathione pathways (in Hungarian). Lab. Diagn. 15, 248-249 (1998)."},{"key":"32","doi-asserted-by":"crossref","unstructured":"32) Ulubelen, A.; Topcu, G.; Eri\u015f, C.; S\u00f6nmez, U.; Kartal, M. et al. Terpenoids from Salvia sclarea. Phytochem. 36, 971-974 (1994).","DOI":"10.1016\/S0031-9422(00)90474-6"},{"key":"33","unstructured":"33) Jensen, T.; Deckert, T. Diabetic retinopathy, nephropathy and neuropathy. Generalized vascular damage in insulin-dependent diabetic patients. Hor. Met. Res. Suppl. Series. 26, 68-70 (1992)."},{"key":"34","doi-asserted-by":"crossref","unstructured":"34) Wang, J.; Liu, H.; Li, N.; Zhang, Q.; Zhang, H. The protective effect of fucoidan in rats with streptozotocin-induced diabetic nephropathy. Mar. Drugs 12, 3292-3306 (2014).","DOI":"10.3390\/md12063292"},{"key":"35","doi-asserted-by":"crossref","unstructured":"35) Sun, Y.M.; Su, Y.; Li, J.; Wang, L.F. Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy. Biochem. Biophys. Res. Commun. 433, 359-361 (2013).","DOI":"10.1016\/j.bbrc.2013.02.120"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36) Furukawa, S.; Fujita, T.; Shimabukuro, M.; Iwaki, M.; Yamada, Y. et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114, 1752-1761 (2017).","DOI":"10.1172\/JCI200421625"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37) Das, J.; Sil, P.C. Taurine ameliorates alloxan-induced diabetic renal injury, oxidative stress-related signaling pathways and apoptosis in rats. Amino acids 43, 1509-1523 (2012).","DOI":"10.1007\/s00726-012-1225-y"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38) Jang, Y.Y.; Song, J.H.; Shin, Y.K.; Han, E.S.; Lee, C.S. Protective effect of boldine on oxidative mitochondrial damage in streptozotocin-induced diabetic rats. Pharmacol. Res. 42, 361-371 (2000).","DOI":"10.1006\/phrs.2000.0705"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39) P\u00e9rez-Gutierrez, R.M.; Garc\u00eda-Campoy, A.H.; Paredes-Carrera, S.P.; Mu\u00f1iz-Ramirez, A.; Mota-Flores, J.M.; Flores-Valle, S.O. 3&apos;-O-\u03b2-d-Glucopyranosyl-\u03b1,4,2&apos;,4&apos;,6&apos;-pentahydroxy-dihydrochalcone, from bark of Eysenhardtia polystachya prevents diabetic nephropathy via inhibiting protein glycation in STZ-nicotinamide induced diabetic mice. 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