{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T20:23:00Z","timestamp":1788812580514,"version":"build-2803163510"},"reference-count":36,"publisher":"Japan Oil Chemists' Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Oleo Sci."],"published-print":{"date-parts":[[2026]]},"DOI":"10.5650\/jos.ess25164","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T22:12:15Z","timestamp":1769897535000},"page":"159-168","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of Antioxidant Activity and Phenolic Content of Medicinal Plants Extracted by Ethanol, Methanol, and Water"],"prefix":"10.5650","volume":"75","author":[{"given":"Burcu","family":"\u00c7akmak Sancar","sequence":"first","affiliation":[{"name":"Department of Nutrition and Dietetics, Faculty of Health Sciences, \u0130stanbul Esenyurt University, \u0130stanbul 34510, T\u00dcRKIYE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halil \u0130brahim","family":"Binici","sequence":"additional","affiliation":[{"name":"Department of Food Technology, Vocational School, \u0130stanbul Esenyurt University, \u0130stanbul 34510, T\u00dcRK\u0130YE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meryem","family":"Akhan","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics, Faculty of Health Sciences, \u0130stanbul Esenyurt University, \u0130stanbul 34510, T\u00dcRKIYE"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"3621","reference":[{"key":"1","first-page":"1","volume":"2","year":"2019","unstructured":"1) Kaurinovic, B.; Vastag, D. Flavonoids and phenolic acids as potential natural antioxidants. Antioxidants 2, 1-14 (2019). doi:10.5772\/intechopen.83731","journal-title":"Antioxidants","ISSN":"https:\/\/id.crossref.org\/issn\/2076-3921","issn-type":"print"},{"key":"2","doi-asserted-by":"publisher","unstructured":"2) Alara, O.R.; Abdurahman, N.H.; Ukaegbu, C.I. Extraction of phenolic compounds: A review. Curr. Res. Food Sci. 4, 200-214 (2021). doi: 10.1016\/j.crfs.2021.03.011","DOI":"10.1016\/j.crfs.2021.03.011"},{"key":"3","doi-asserted-by":"publisher","unstructured":"3) Zhang, Y.; Cai, P.; Cheng, G. ; Zhang, Y. A brief review of phenolic compounds identified from plants: Their extraction, analysis, and biological activity. Nat. Prod. Commun. 17, 1934578X211069721 (2022). doi: 10.1177\/1934578X211069721.","DOI":"10.1177\/1934578X211069721"},{"key":"4","doi-asserted-by":"publisher","unstructured":"4) Shi, L.; Zhao, W.; Yang, Z.; Subbiah, V.; Suleria, H.A.R. Extraction and characterization of phenolic compounds and their potential antioxidant activities. Environ. Sci. Poll. Res. 29, 81112-81129 (2022). doi: 10.1007\/s11356-022-23337-6","DOI":"10.1007\/s11356-022-23337-6"},{"key":"5","doi-asserted-by":"publisher","unstructured":"5) Yeshi, K.; Crayn, D.; Ritmejeryt\u0117, E.; Wangchuk, P. Plant secondary metabolites produced in response to abiotic stresses has potential application in pharmaceutical product development. Molecules 27, 313 (2022). doi: 10.3390\/molecules27010313","DOI":"10.3390\/molecules27010313"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6) Turkmen, N.; Sari, F.; Velioglu, Y.S. Effects of extraction solvents on concentration and antioxidant activity of black and black mate tea polyphenols determined by ferrous tartrate and Folin-Ciocalteu methods. Food Chem. 99, 835-841 (2006). doi: 10.1016\/j.foodchem.2005.08.034","DOI":"10.1016\/j.foodchem.2005.08.034"},{"key":"7","doi-asserted-by":"publisher","unstructured":"7) Do, Q.D.; Angkawijaya, A.E.; Tran-Nguyen, P.L.; Huynh, L.H.; Soetaredjo, F.E. et al. Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica. J. Food Drug Anal. 22, 296-302 (2014). doi: 10.1016\/j.jfda.2013.11.001","DOI":"10.1016\/j.jfda.2013.11.001"},{"key":"8","doi-asserted-by":"publisher","unstructured":"8) Dai, J.; Mumper, R.J. Plant phenolics: extraction, analysis and their antioxidant and anticancer properties. Molecules 15, 7313-7352 (2010). doi: 10.3390\/molecules15107313","DOI":"10.3390\/molecules15107313"},{"key":"9","doi-asserted-by":"publisher","unstructured":"9) Pe\u00f1a, F.; Valencia, S.; Tereuc\u00e1n, G.; Nahuelcura, J.; Jim\u00e9nez-Aspee, F. et al. Bioactive compounds and antioxidant activity in the fruit of rosehip (Rosa canina L. and Rosa rubiginosa L.). Molecules 28, 3544 (2023). doi: 10.3390\/molecules28083544","DOI":"10.3390\/molecules28083544"},{"key":"10","unstructured":"10) Al-Hashimi, A.G. Antioxidant and antibacterial activities of Hibiscus sabdariffa L. extracts. African J. Food Sci. 6, 506-511 (2012). doi:10.\u00a55897\/AJFS12.099"},{"key":"11","doi-asserted-by":"publisher","unstructured":"11) Montalvo-Gonz\u00e1lez, E.; Villagr\u00e1n, Z.; Gonz\u00e1lez-Torres, S.; I\u00f1iguez-Mu\u00f1oz, L.E.; Isiordia-Espinoza, M.A. et al. Physiological effects and human health benefits of Hibiscus sabdariffa: A review of clinical trials. Pharmaceuticals 15, 464 (2022). doi: 10.3390\/ph15040464","DOI":"10.3390\/ph15040464"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12) Virchea, L.I.; Gligor, F.G.; Frum, A.; Mironescu, M.; Myachikova, N.I.; Georgescu, C. Phytochemical analysis and antioxidant assay of Melissa officinalis L.(lemon balm). in BIO Web of Conferences (Vol. 40, p. 02004). EDP Sciences (2021). doi: 10.1051\/bioconf\/20214002004","DOI":"10.1051\/bioconf\/20214002004"},{"key":"13","doi-asserted-by":"publisher","unstructured":"13) Wojdy\u0142o, A.; Nowicka, P.; Turkiewicz, I.P.; Tkacz, K.; Hern\u00e1ndez, F. Comparison of bioactive compounds and health promoting properties of fruits and leaves of apple, pear and quince. Sci. Rep. 11, 20253 (2021). doi: 10.1038\/s41598-021-99293-x","DOI":"10.1038\/s41598-021-99293-x"},{"key":"14","doi-asserted-by":"publisher","unstructured":"14) Ghorbani, A.; Esmaeilizadeh, M. Pharmacological properties of Salvia officinalis and its components. J. Tradit. Complement. Med. 7, 433-440 (2017). doi: 10.1016\/j.jtcme.2016.12.014","DOI":"10.1016\/j.jtcme.2016.12.014"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Jasicka-Misiak, I.; Makowicz, E.; Stanek, N. Chromatographic fingerprint, antioxidant activity, and colour characteristic of Polish goldenrod (Solidago virgaurea L.) honey and flower. Euro. Food Research Tech. 244, 1169-1184 (2018). doi: 10.1007\/s00217-017-3011-0","DOI":"10.1007\/s00217-018-3034-3"},{"key":"16","doi-asserted-by":"publisher","unstructured":"16) Devkota, H.P.; Paudel, K.R.; Khanal, S.; Baral, A.; Panth, N. et al. Stinging nettle (Urtica dioica L.): Nutritional composition, bioactive compounds, and food functional properties. Molecules 27, 5219 (2022). doi: 10.3390\/molecules27165219","DOI":"10.3390\/molecules27165219"},{"key":"17","doi-asserted-by":"publisher","unstructured":"17) Zhou, S.; Li, Z.; Song, H.; Hu, H.; Ma, S. et al. Recent advances in tea seeds (Camellia sinensis (L.) O. Kuntze): Active ingredients, health effects, and potential applications. Tren. Food Sci. Tech. 141, 104192 (2023). doi: 10.1016\/j.tifs.2023.104192","DOI":"10.1016\/j.tifs.2023.104192"},{"key":"18","unstructured":"18) Cemero\u011flu, B. Meyve ve Sebze \u0130\u015fleme Teknolojisi 1. Cilt. G\u0131da Teknolojisi Derne\u011fi Yay\u0131nlar\u0131 No: 38, Ankara, 77-88 (2009). (in Turkish)"},{"key":"19","doi-asserted-by":"publisher","unstructured":"19) Binici, H.I.; \u015eat, \u0130.G.; Aoudeh, E. The effect of different drying methods on nutritional composition and antioxidantactivity of purslane (Portulaca oleracea). Turkish J. Agri. For. 45, 680-689 (2021). doi: 10.3906\/tar-2012-60","DOI":"10.3906\/tar-2012-60"},{"key":"20","doi-asserted-by":"publisher","unstructured":"20) Ko\u00e7ak, E.; Demircan, E.; \u00d6z\u00e7elik, B. Antioxidant capacities and phenolic profiles of Ottoman strawberry fruit and Ottoman strawberry jam. Ecol. Life Sci. 13, 119-130 (2018). doi: 10.12739\/NWSA.2018.13.3.5A0101","DOI":"10.12739\/NWSA.2018.13.3.5A0101"},{"key":"21","unstructured":"21) Saad, R.; Asmani, F.; Saad, M.; Hussain, M.; Khan, J. et al. A new approach for predicting antioxidant property of herbal extracts. Int. J. Pharmacogn. Phytochem. Res, 7, 166-174 (2015)."},{"key":"22","doi-asserted-by":"publisher","unstructured":"22) Tak, A.A.; Kakde, U.B. Assessment of air pollution tolerance index of plants: A comparative study. Int. J. Pharm. Pharm. Sci. 9(7), 83-89 (2017). doi: 10.22159\/ijpps.2017v9i7.18447","DOI":"10.22159\/ijpps.2017v9i7.18447"},{"key":"23","doi-asserted-by":"publisher","unstructured":"23) P\u0119kal, A.; Pyrzynska, K. Evaluation of aluminium complexation reaction for flavonoid content assay. Food Anal. Methods 7, 1776-1782 (2011). doi: 10.1007\/s12161-014-9814-x","DOI":"10.1007\/s12161-014-9814-x"},{"key":"24","doi-asserted-by":"publisher","unstructured":"24) Chatepa, L.E.C.; Mwamatope, B.; Chikowe, I.; Masamba, K. G. Effects of solvent extraction on the phytoconstituents and in vitro antioxidant activity properties of leaf extracts of the two selected medicinal plants from Malawi. BMC Complement. Med. Ther.24, 317 (2024). doi: 10.1186\/s12906-024-04619-7","DOI":"10.1186\/s12906-024-04619-7"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25) Tripathi, S.; Singh, S.; Mishra, N.; Mishra, N. The impact of solvent polarity on the phenolic and antioxidant capacity of green coffee beans (Robusta species) extracts. Curr. Rese. Nutr. Food Sci. J. 13, 926-936 (2025). doi: 10.12944\/CRNFSJ.13.2.27","DOI":"10.12944\/CRNFSJ.13.2.27"},{"key":"26","unstructured":"26) Ri, H.I.; Kim, C.S.; Pak, U.H.; Kang, M.S.; Kim, T. . Effect of different polarity solvents on total phenols and flavonoids content, and in-vitro antioxidant properties of flowers extract from Aurea helianthus. arXiv preprint arXiv:1906.12006 (2019). doi: 10.48550\/arXiv.1906.12006"},{"key":"27","doi-asserted-by":"publisher","unstructured":"27) Sadowska, U.; Armenta Villavicencio, R.; Dziadek, K.; Skoczylas, J.; Sadowski, S.K.; Kope\u0107, A. The identification of polyphenolic compounds and the determination of antioxidant activity in extracts and infusions of peppermint, lemon balm and lavender. Appl. Sci. 14, 699 (2024). doi:10.3390\/app14020699","DOI":"10.3390\/app14020699"},{"key":"28","doi-asserted-by":"publisher","unstructured":"28) Miron, T.L.; Herrero, M.; Ib\u00e1\u00f1ez, E. Enrichment of antioxidant compounds from lemon balm (Melissa officinalis) by pressurized liquid extraction and enzyme-assisted extraction. J. Chromat. A 1288, 1-9 (2013). doi:10.1016\/j.chroma.2013.02.075","DOI":"10.1016\/j.chroma.2013.02.075"},{"key":"29","doi-asserted-by":"publisher","unstructured":"29) Ordaz, J.J.; Hern\u00e1ndez, J.M.; Ram\u00edrez-God\u00ednez, J.; Casta\u00f1eda-Ovando, A.; Gonz\u00e1lez-Olivares, L.G.; Contreras-L\u00f3pez, E. Bioactive compounds in aqueous extracts of lemon balm (Melissa officinalis) cultivated in Mexico. Arch. Latinoam. Nutr. 68, 268-279 (2018). doi:10.37527\/2018.68.3.009","DOI":"10.37527\/2018.68.3.009"},{"key":"30","doi-asserted-by":"publisher","unstructured":"30) Yoo, G.; Lee, I.K.; Park, S.; Kim, N.; Park, J.H.; Kim, S.H. Optimization of extraction conditions for phenolic acids from the leaves of Melissa officinalis L. using response surface methodology. Pharm. Mag. 14(54), 155 (2018). doi:10.4103\/pm.pm_70_17","DOI":"10.4103\/pm.pm_70_17"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31) George, J.; Edwards, D.; Pun, S.; Williams, D. Evaluation of antioxidant capacity (ABTS and CUPRAC) and total phenolic content (Folin-Ciocalteu) assays of selected fruit, vegetables, and spices. Inter. J. Food Sci. 2022, 2581470 (2022). doi:10.1155\/2022\/2581470","DOI":"10.1155\/2022\/2581470"},{"key":"32","doi-asserted-by":"publisher","unstructured":"32) Teofilovi\u0107, B.; Gligori\u0107, E.; Nini\u0107, M.; Vukmirovi\u0107, S.; Gagi\u0107, \u017d. et al. Green extraction combined with chemometric approach: Profiling phytochemicals and antioxidant properties of ten species of the Lamiaceae family. Separations 12(6), 155 (2025). doi:10.3390\/separations12060155","DOI":"10.3390\/separations12060155"},{"key":"33","doi-asserted-by":"publisher","unstructured":"33) W\u00f3jcik-Borowska, K.; W\u00f3jciak, W.; \u017buk, M.; Luchowski, P.; Skalska-Kami\u0144ska, A. et al. Oxidative stress protection and anti-\u0131nflammatory activity of polyphenolic fraction from Urtica dioica: In vitro study using human skin cells. Molecules 30, 2515 (2025). doi:10.3390\/molecules30122515.","DOI":"10.3390\/molecules30122515"},{"key":"34","doi-asserted-by":"publisher","unstructured":"34) Mohammed, E.A.; Abdalla, I.G.; Alfawaz, M.A.; Mohammed, M.A.; Al Maiman, S.A. et al. Effects of extraction solvents on the total phenolic content, total flavonoid content, and antioxidant activity in the aerial part of root vegetables. Agriculture 12, 1820 (2022). doi:10.3390\/agriculture12111820","DOI":"10.3390\/agriculture12111820"},{"key":"35","doi-asserted-by":"publisher","unstructured":"35) Karprakhon, V.; Sirisangsawang, R.; Kaewkroek, K.; Rojviroon, T.; Phetyim, N.; Sukpancharoen, S. Optimization of combined subcritical water and CO<sub>2<\/sub> extraction for enhanced phenolics and antioxidant activity from coffee byproducts. Scient. Rep. 15, 8964 (2025). doi:10.1038\/s41598-025-92401-1","DOI":"10.1038\/s41598-025-92401-1"},{"key":"36","doi-asserted-by":"publisher","unstructured":"36) Samid, I.; Khouya, T.; Elbouny, H.; Sellam, K.; Alem, C. Quantification of phytochemical and antioxidant properties of aqueous apple extracts from the high atlas mountains in Morocco and their anti-inflammatory effect on Wistar rats. Scient. Afr. 22, e01897 (2023). doi:10.1016\/j.sciaf.2023.e01897","DOI":"10.1016\/j.sciaf.2023.e01897"}],"container-title":["Journal of Oleo Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jos\/75\/2\/75_jos.ess25164\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T03:36:14Z","timestamp":1770435374000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jos\/75\/2\/75_jos.ess25164\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.5650\/jos.ess25164","relation":{},"ISSN":["1345-8957","1347-3352"],"issn-type":[{"value":"1345-8957","type":"print"},{"value":"1347-3352","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"article-number":"jos.ess25164"}}