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Physicochemical characteristics of cannabis seed oil (Cannabis sativa L.) from different varieties grown in the conditions of the Syrdarya region. E3S Web Conf. 463, 01004 (2023). doi:10.1051\/e3sconf\/202346301004.","DOI":"10.1051\/e3sconf\/202346301004"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9) Rahman, S.; Rivai, M.A.; Dasrul, D.; Ayu, O. Effect of hemp seed oil on accelerating wound healing: evaluation of wound size reduction, epithelialization, granulation tissue formation, and vascularization in murine models. Narra J. 5, e1878 (2025). doi:10.52225\/narra.v5i1.1878.","DOI":"10.52225\/narraj.v5i1.1878"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10) Lima, M.S.; Oliveira, L. Lipid oxidation in meat: mechanisms and protective factors -a review. Ci\u00eanc. Tecnol. Aliment. 38, 7-15 (2018). doi:10.1590\/fst.32518.","DOI":"10.1590\/fst.32518"},{"key":"11","unstructured":"11) Pokorn\u00fd, J. Factors affecting the oxidative stability of lipids. in Deep Frying: Chemistry, Nutrition, and Practical Applications 2nd ed., AOCS Press, pp. 185-221 (2007)."},{"key":"12","unstructured":"12) Chen, M.; Li, M.; Zhou, B., et al. Methods of microencapsulation of vegetable oil: principles, stability and applications - a minireview. J. AOAC Int. 105, 1467-1473 (2022)."},{"key":"13","doi-asserted-by":"publisher","unstructured":"13) Menin, A.; Zanoni, F.; Vakarelova, M.; Chignola, R.; Don\u00e0, G., et al. Effects of microencapsulation by ionic gelation on the oxidative stability of flaxseed oil. Food Chem. 269, 293-299 (2018). doi:10.1016\/j.foodchem.2018.06.144.","DOI":"10.1016\/j.foodchem.2018.06.144"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14) Choe, E.; Min, D.B. Mechanisms and factors for edible oil oxidation. Compr. Rev. Food Sci. Food Saf. 5, 169-186 (2006).","DOI":"10.1111\/j.1541-4337.2006.00009.x"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15) Shahidi, F.; Zhong, Y. Lipid oxidation and improving oxidative stability. Chem. Soc. Rev. 39, 4067-4079 (2010).","DOI":"10.1039\/b922183m"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16) Gharsallaoui, A.; Roudaut, G.; Chambin, O.; Voilley, A.; Saurel, R. Applications of spray-drying in microencapsulation. Food Res. Int. 40, 1107-1121 (2007).","DOI":"10.1016\/j.foodres.2007.07.004"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17) Dickinson, E. Biopolymer-based microencapsulation systems. Food Hydrocoll. 68, 219-231 (2017).","DOI":"10.1016\/j.foodhyd.2016.06.024"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18) De Jong, G.A.H.; Koppelman, S.J. Transglutaminase catalyzed reactions. J. Food Sci. 67, 2798-2806 (2002).","DOI":"10.1111\/j.1365-2621.2002.tb08819.x"},{"key":"19","doi-asserted-by":"publisher","unstructured":"19) Jafari, H.; Ghaffari-Bohlouli, P.; Niknezhad, S.V.; Abedi, A.; Izadifar, Z., et al. Tannic acid: a versatile polyphenol for design of biomedical hydrogels. J. Mater. Chem. B 10, 5873-5912 (2022). doi:10.1039\/D2TB01056A.","DOI":"10.1039\/D2TB01056A"},{"key":"20","first-page":"333","volume":"14","year":"2010","unstructured":"20) Uluata, S. Effect of extraction method on biochemical properties and oxidative stability of apricot seed oil. Akademik G\u0131da 14, 333-340 (2010).","journal-title":"Akademik G\u0131da","ISSN":"https:\/\/id.crossref.org\/issn\/1304-7582","issn-type":"print"},{"key":"21","unstructured":"21) American Oil Chemists&apos; Society (AOCS). Official methods and recommended practices of the American Oil Chemists&apos; Society (5th ed.). AOCS Press (1998)."},{"key":"22","unstructured":"22) Food Safety and Standards Authority of India (FSSAI). Manual of methods of analysis of foods: oils and fats. FSSAI, New Delhi, India (2015). https:\/\/fssai.gov.in\/"},{"key":"23","doi-asserted-by":"publisher","unstructured":"23) Lazaridou, A.; Biliaderis, C.G.; Bacandritsos, N.; Sabatini, A.G. Composition, thermal and rheological behaviour of selected Greek honeys. J. Food Eng. 64, 9-21 (2004). doi:10.1016\/j.jfoodeng.2003.09.007.","DOI":"10.1016\/j.jfoodeng.2003.09.007"},{"key":"24","unstructured":"24) AOCS. Of\ufb01cial methods and recommended practices of the American Oil Chemists Societ. AOCS Press, Champaign, Color of Fats and Oils, Lovibond (Wesson) Wesson Method Using Color Glasses Calibrated in Accordance with the AOCS-Tintometer Color Scale Cc 13b-45 (2017)."},{"key":"25","unstructured":"25) H\u0131\u015f\u0131l, Y. Instrumental food analysis-II. 4th ed., Ege University Faculty of Engineering Textbooks, \u0130zmir, 39 p. (2004)."},{"key":"26","unstructured":"26) Tanac\u0131, H. Sterol analysis in vegetable oils by GC-FID, GC Application Note. Istanbul (2013)."},{"key":"27","unstructured":"27) Rodriguez, L.G.; Wu, X.; Guan, J.L. Wound-healing assay. in Cell Migration: Developmental Methods and Protocols (Guan, J.L. eds.), Humana Press, Totowa (NJ), pp. 23-29 (2005)."},{"key":"28","unstructured":"28) P\u00fcsk\u00fclc\u00fc, H.; \u0130kiz, F. Introduction to statistics. Bilgehan Press, Bornova-Izmir (1989)."},{"key":"29","doi-asserted-by":"publisher","unstructured":"29) Vlachos, N.; Skopelitis, Y.; Psaroudaki, M.; Konstantinidou, V.; Chatzilazarou, A.; Tegou, E. Applications of Fourier transform-infrared spectroscopy to edible oils. Anal. Chim. Acta 573-574, 459-465 (2006). doi:10.1016\/j.aca.2006.05.034.","DOI":"10.1016\/j.aca.2006.05.034"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30) \u00d6\u011f\u00fctc\u00fc, M.; Arifo\u011flu, N.; Yilmaz, E. 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Structuring of cold pressed oils: evaluation of the physicochemical characteristics and microstructure of white beeswax oleogels. Gels 9, 216 (2023). doi:10.3390\/gels9030216.","DOI":"10.3390\/gels9030216"},{"key":"34","doi-asserted-by":"publisher","unstructured":"34) Guill\u00e9n, M.D.; Cabo, N. Infrared spectroscopy in the study of edible oils and fats. J. Sci. Food Agric. 75, 1-11 (1997). doi:10.1002\/(SICI)1097-0010(199709)75:1&lt;1::AID-JSFA842&gt;3.0.CO;2-R.","DOI":"10.1002\/(SICI)1097-0010(199709)75:1<1::AID-JSFA842>3.0.CO;2-R"},{"key":"35","doi-asserted-by":"publisher","unstructured":"35) Lerma-Garc\u00eda, M.J.; Ramis-Ramos, G.; Herrero-Mart\u00ednez, J.M.; Sim\u00f3-Alfonso, E.F. Authentication of extra virgin olive oils by Fourier-transform infrared spectroscopy. Food Chem. 118, 78-83 (2010). doi:10.1016\/j.foodchem.2009.04.102.","DOI":"10.1016\/j.foodchem.2009.04.102"},{"key":"36","doi-asserted-by":"publisher","unstructured":"36) Teh, S.S.; Birch, J. Physicochemical and antinutritional attributes of whole-processed hemp (Cannabis sativa L.) seeds and roasted hull-less pumpkin (Cucurbita maxima) seeds. Food Chem. 139, 320-326 (2013). doi:10.1016\/j.foodchem.2013.01.020.","DOI":"10.1016\/j.foodchem.2013.01.020"},{"key":"37","unstructured":"37) Aladi\u0107, K.; Jarni, K.; Barbir, T.; Vidovi\u0107, S.; Vladi\u0107, J., et al. Influence of extraction conditions on leftovers of hemp cake and hemp oil. J. Food Sci. Technol. 52, 4227-4236 (2015). doi:10.1007\/s13197-014-1498-8."},{"key":"38","doi-asserted-by":"publisher","unstructured":"38) Latif, S.; Anwar, F. Physicochemical studies of hemp (Cannabis sativa) seed oil using enzyme-assisted cold-pressing. Eur. J. Lipid Sci. Technol. 111, 1042-1048 (2009). Portico. doi:10.1002\/ejlt.200900008.","DOI":"10.1002\/ejlt.200900008"},{"key":"39","doi-asserted-by":"publisher","unstructured":"39) Morar, M.V.; Dragan, K.; Bele, C.; Matea, C.; Tarta, I., et al. Researches regarding the processing of the hemp seed by cold pressing. Bull. Univ. Agric. Sci. Vet. Med. Cluj-Napoca Agric. 67 (2010). doi:10.15835\/buasvmcn-agr:5111.","DOI":"10.15835\/buasvmcn-agr:5111"},{"key":"40","doi-asserted-by":"publisher","unstructured":"40) Min, D.B. Analyses of flavor qualities of vegetable oils by gas chromatography. J. Am. Oil Chem. Soc. 60, 544-545 (1983). Portico. doi:10.1007\/bf02679783.","DOI":"10.1007\/BF02679783"},{"key":"41","doi-asserted-by":"publisher","unstructured":"41) Dom\u00ednguez, H. Enzyme-assisted hexane extraction of soya bean oil. Food Chem. 54, 223-231 (1995). doi:10.1016\/0308-8146(95)00018-e.","DOI":"10.1016\/0308-8146(95)00018-E"},{"key":"42","doi-asserted-by":"publisher","unstructured":"42) Ranalli, A.; De Mattia, G. Characterization of olive oil produced with a new enzyme processing aid. J. Am. Oil Chem. Soc. 74, 1105-1113 (1997). Portico. doi:10.1007\/s11746-997-0032-1.","DOI":"10.1007\/s11746-997-0032-1"},{"key":"43","doi-asserted-by":"publisher","unstructured":"43) Siger, A.; Nogala-Kalucka, M.; Lampart-Szczapa, E. The content and antioxidant activity of phenolic compounds in cold-pressed plant oils. J. Food Compos. Anal. 21, 150-154 (2008). doi:10.1016\/j.jfca.2007.09.002.","DOI":"10.1016\/j.jfca.2007.09.002"},{"key":"44","doi-asserted-by":"publisher","unstructured":"44) Parker, T.D.; Adams, D.A.; Zhou, K.; Harris, M.; Yu, L. Fatty acid composition and oxidative stability of cold-pressed edible seed oils. J. Food Sci. 68, 1240-1243 (2003). doi:10.1111\/j.1365-2621.2003.tb09632.x.","DOI":"10.1111\/j.1365-2621.2003.tb09632.x"},{"key":"45","doi-asserted-by":"publisher","unstructured":"45) Latif, S.; Anwar, F.; Ashraf, M. Physicochemical characteristics and fatty acid composition of hemp (Cannabis sativa L.) seed oil. J. Am. Oil Chem. Soc. 86, 183-189 (2009). doi:10.1007\/s11746-008-1328-5.","DOI":"10.1007\/s11746-008-1328-5"},{"key":"46","doi-asserted-by":"publisher","unstructured":"46) Molero G\u00f3mez, A. Quality of borage seed oil extracted by liquid and supercritical carbon dioxide. Chem. Eng. J. 88, 103-109 (2002). doi:10.1016\/s1385-8947(01)00260-1.","DOI":"10.1016\/S1385-8947(01)00260-1"},{"key":"47","doi-asserted-by":"crossref","unstructured":"47) Gunstone, F.D. Vegetable oils in food technology: composition, properties and uses (2nd ed.). Wiley-Blackwell (2011). doi:10.1002\/9781444339925.ch1.","DOI":"10.1002\/9781444339925"},{"key":"48","unstructured":"48) Codex Alimentarius Commission. Standard for named vegetable oils (CODEX STAN 210-1999). FAO\/WHO (1999)."},{"key":"49","doi-asserted-by":"publisher","unstructured":"49) Kabutey, A.; Her\u00e1k, D.; Mizera, \u010c. Assessment of quality and efficiency of cold-pressed oil from selected oilseeds. Foods 12, 3636 (2023). doi:10.3390\/foods12193636.","DOI":"10.3390\/foods12193636"},{"key":"50","doi-asserted-by":"publisher","unstructured":"50) Da Porto, C.; Decorti, D.; Tubaro, F. Fatty acid composition and oxidation stability of hemp (Cannabis sativa L.) seed oil extracted by supercritical carbon dioxide. Ind. Crops Prod. 36, 401-404 (2012). doi:10.1016\/j.indcrop.2011.09.015.","DOI":"10.1016\/j.indcrop.2011.09.015"},{"key":"51","doi-asserted-by":"crossref","unstructured":"51) Fellows, P.J. Food processing technology: principles and practice (3rd ed.). Woodhead Publishing (2009). doi:10.1533\/9781845696344.","DOI":"10.1533\/9781845696344"},{"key":"52","doi-asserted-by":"publisher","unstructured":"52) Mart\u00ednez, M.L.; Mattea, M.A.; Maestri, D.M. Pressing and supercritical carbon dioxide extraction of walnut oil. J. Food Eng. 88, 399-404 (2008). doi:10.1016\/j.jfoodeng.2008.02.026.","DOI":"10.1016\/j.jfoodeng.2008.02.026"},{"key":"53","doi-asserted-by":"publisher","unstructured":"53) Teh, S.S.; Birch, J. Physicochemical and quality characteristics of cold-pressed hemp, flax and canola seed oils. J. Food Compos. Anal. 30, 26-31 (2013). doi:10.1016\/j.jfca.2013.01.004.","DOI":"10.1016\/j.jfca.2013.01.004"},{"key":"54","doi-asserted-by":"publisher","unstructured":"54) Aladi\u0107, K. Cold pressing and supercritical CO<sub>2<\/sub> extraction of hemp (Cannabis sativa) seed oil. Chem. Biochem. Eng. Q. 28, 481-490 (2015). doi:10.15255\/cabeq.2013.1895.","DOI":"10.15255\/CABEQ.2013.1895"},{"key":"55","unstructured":"55) Abh\u0131roop, M. Invest\u0131gat\u0131on of d\u0131fferent extract\u0131on methods for hemp seeds. A Thesis Submitted to the College of Graduate and Postdoctoral Studies in Partial Fulfillment of the Requirements For the Degree of Master of Science in the Department of Chemical and Biological Engineering University of Saskatchewan Saskatoon. Mookerjee-Thes\u0131s-2020."},{"key":"56","doi-asserted-by":"crossref","unstructured":"56) Dawodu, M.O.; Olutona, G.O.; Obimakinde, S.O. Effect of temperature on the chemical characteristics of vegetable oils consumed in Ibadan, Nigeria. Pak. J. Nutr. 14, 698-707 (2015). doi:10.3923\/pjn.2015.698.707.","DOI":"10.3923\/pjn.2015.698.707"},{"key":"57","unstructured":"57) Codex Alimentarius International Food Standards. Codex standard for named vegetable oils CX-STAN 210-1999. Codex Alimentarius 8, 11-25 (2001)."},{"key":"58","unstructured":"58) Borhade, S.S. Chemical composition and characterization of hemp (Cannabis sativa) seed oil and essential fatty acids by HPLC method. Arch. Appl. Sci. Res. 5, 5 (2013)."},{"key":"59","doi-asserted-by":"crossref","unstructured":"59) Frankel, E.N. Hydroperoxide formation. Lipid Oxidation 25-50 (2012). doi:10.1533\/9780857097927.25.","DOI":"10.1533\/9780857097927.25"},{"key":"60","unstructured":"60) Ardal\u0131, Y. Unit operations II laboratory experiment 3: density-viscosity measurements. Samsun (2020)."},{"key":"61","unstructured":"61) Ministry of National Education (MEB). Analysis of edible oils 1, food technology department, course module. Ankara (2010)."},{"key":"62","doi-asserted-by":"crossref","unstructured":"62) Shahidi, F.; Wanasundara, P. Extraction and analysis of lipids. Food Lipids pp. 132-161 (2002). doi:10.1201\/9780203908815.ch5.","DOI":"10.1201\/9780203908815.ch5"},{"key":"63","doi-asserted-by":"publisher","unstructured":"63) Zanardi, I.; Travagli, V.; Gabbrielli, A.; Chiasserini, L.; Bocci, V. Physico-chemical characterization of sesame oil derivatives. Lipids 43, 877-886 (2008). Portico. doi:10.1007\/s11745-008-3218-x.","DOI":"10.1007\/s11745-008-3218-x"},{"key":"64","doi-asserted-by":"publisher","unstructured":"64) Kosti\u0107, M.D.; Jokovi\u0107, N.M.; Stamenkovi\u0107, O.S.; Rajkovi\u0107, K.M.; Mili\u0107, P.S.; Veljkovi\u0107, V.B. Optimization of hempseed oil extraction by n-hexane. Ind. Crops Prod. 48, 133-143 (2013). doi:10.1016\/j.indcrop.2013.04.028.","DOI":"10.1016\/j.indcrop.2013.04.028"},{"key":"65","doi-asserted-by":"publisher","unstructured":"65) Vonapartis, E.; Aubin, M.P.; Seguin, P.; Mustafa, A.F.; Charron, J.B. Seed composition of ten industrial hemp cultivars approved for production in Canada. J. Food Compos. Anal. 39, 8-12 (2015). doi:10.1016\/j.jfca.2014.11.004.","DOI":"10.1016\/j.jfca.2014.11.004"},{"key":"66","doi-asserted-by":"crossref","unstructured":"66) Qiu, X.; Hong, H.; Datla, N.; Reed, D.W.; Truksa, M., et al. Production of nutraceutical fatty acids in oilseed crops. Adv. Res. Plant Lipids 403-406 (2003). doi:10.1007\/978-94-017-0159-4_94.","DOI":"10.1007\/978-94-017-0159-4_94"},{"key":"67","doi-asserted-by":"publisher","unstructured":"67) Anwar, F.; Latif, S.; Ashraf, M. Analytical characterization of hemp (Cannabis sativa) seed oil from different agro-ecological zones of Pakistan. J. Am. Oil Chem. Soc. 83, 323-329 (2006). Portico. doi:10.1007\/s11746-006-1207-x.","DOI":"10.1007\/s11746-006-1207-x"},{"key":"68","unstructured":"68) Deferne, J.L.; Pate, D.W. Hemp seed oil: a source of valuable essential fatty acids. J. Int. Hemp Assoc. 3, 4-7 (1996)."},{"key":"69","doi-asserted-by":"publisher","unstructured":"69) Jeong, T.M.; Itoh, T.; Tamura, T.; Matsumoto, T. Analysis of sterol fractions from twenty vegetable oils. Lipids 9, 921-927 (1974). Portico. doi:10.1007\/bf02532620.","DOI":"10.1007\/BF02532620"},{"key":"70","unstructured":"70) Karc\u0131er, M. (2021) Physical and chemical composition of cannabis seed and seed oils obtained by different extraction methods. Afyon Kocatepe University, Institute of Science, Master&apos;s Thesis (No: 655285)."},{"key":"71","unstructured":"71) Turkish Food Codex. Communiqu\u00e9 on vegetable oils named by plant name (Communiqu\u00e9 No: 2012\/29). Official Gazette, Ankara (2012)."},{"key":"72","doi-asserted-by":"crossref","unstructured":"72) Dhadwal, G.; Kirchhof, M.G. The risks and benefits of cannabis in the dermatology clinic. J. Cutan. Med. Surg. 22, 194-199 (2018).","DOI":"10.1177\/1203475417738971"},{"key":"73","doi-asserted-by":"crossref","unstructured":"73) MacCallum, C.A.; Russo, E.B. Practical considerations in medical cannabis administration and dosing. Eur. J. Intern. Med. 49, 12-19 (2018).","DOI":"10.1016\/j.ejim.2018.01.004"},{"key":"74","doi-asserted-by":"publisher","unstructured":"74) Gerasymchuk, M.; Robinson, G.I.; Groves, A.; Haselhorst, L.; Nandakumar, S.; Stahl, C., et al. Phytocannabinoids stimulate rejuvenation and prevent cellular senescence in human dermal fibroblasts. Cells 11, 3939 (2022).","DOI":"10.3390\/cells11233939"},{"key":"75","doi-asserted-by":"crossref","unstructured":"75) Pagano, S.; Coniglio, M.; Valenti, C.; Federici, M.I.; Lombardo, G.; Cianetti, S., et al. Biological effects of cannabidiol on normal human healthy cell populations: systematic review of the literature. Biomed. Pharmacother. 132, 110728 (2020).","DOI":"10.1016\/j.biopha.2020.110728"},{"key":"76","doi-asserted-by":"crossref","unstructured":"76) Zabot, G.L.; Schaefer Rodrigues, F.; Polano Ody, L.; Vin\u00edcius Tres, M.; Herrera, E.; Palacin, H., et al. Encapsulation of bioactive compounds for food and agricultural applications. Polymers (Basel) 14, 4194 (2022).","DOI":"10.3390\/polym14194194"},{"key":"77","doi-asserted-by":"crossref","unstructured":"77) Correia, C.R.; Reis, R.L.; Mano, J.F. Design principles and multifunctionality in cell encapsulation systems for tissue regeneration. Adv. Healthc. Mater. 7, 1701444 (2018).","DOI":"10.1002\/adhm.201701444"},{"key":"78","doi-asserted-by":"publisher","unstructured":"78) Napi\u00f3rkowska, A.; Kurek, M. Coacervation as a novel method of microencapsulation of essential oils a review. Molecules 27, 5142 (2022). doi:10.3390\/molecules27165142.","DOI":"10.3390\/molecules27165142"},{"key":"79","doi-asserted-by":"crossref","unstructured":"79) Mili\u00e1n, Y.E.; Gutierrez, A.; Grageda, M.; Ushak, S. A review on encapsulation techniques for inorganic phase change materials and the influence on their thermophysical properties. Renew. Sustain. Energy Rev. 73, 983-999 (2017).","DOI":"10.1016\/j.rser.2017.01.159"},{"key":"80","doi-asserted-by":"publisher","unstructured":"80) Muhoza, B.; Xia, S.; Wang, X.; Zhang, X.; Li, Y.; Zhang, S. Microencapsulation of essential oils by complex coacervation method: preparation, thermal stability, release properties and applications. Crit. Rev. Food Sci. Nutr. 62, 1363-1382 (2022). doi:10.1080\/10408398.2020.1843132.","DOI":"10.1080\/10408398.2020.1843132"},{"key":"81","doi-asserted-by":"publisher","unstructured":"81) Carvalho da Silva, L.; Castelo, R.M.; Cheng, H.N.; Biswas, A.; Furtado, R.F.; Alves, C.R. Methods of microencapsulation of vegetable oil: principles, stability and applications a minireview. Food Technol. Biotechnol. 60, 308-320 (2022). doi:10.17113\/ftb.60.03.22.7329.","DOI":"10.17113\/ftb.60.03.22.7329"},{"key":"82","doi-asserted-by":"publisher","unstructured":"82) Huang, Q.; Mills, T.; Zhang, Z. The effect of core oil on the encapsulation efficiency and mechanical properties of microcapsules prepared using complex coacervation followed by spray drying\/coating. Int. J. Food Sci. Technol. 60, vvae005 (2025). doi:10.1093\/ijfood\/vvae005.","DOI":"10.1093\/ijfood\/vvae005"},{"key":"83","doi-asserted-by":"publisher","unstructured":"83) Hulkower, K.I.; Herber, R.L. Cell migration and invasion assays as tools for drug discovery. 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